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Major Histocompatibility Complex, Class II, DP alpha 1 Proteins (HLA-DPA1)

HLA-DPA1 belongs to the HLA class II alpha chain paralogues. Additionally we are shipping Major Histocompatibility Complex, Class II, DP alpha 1 Antibodies (54) and Major Histocompatibility Complex, Class II, DP alpha 1 Kits (1) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
HLA-DPA1 3113 P20036
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Top Major Histocompatibility Complex, Class II, DP alpha 1 Proteins at antibodies-online.com

Showing 4 out of 4 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 49 to 54 Days
$6,041.49
Details
HOST_Wheat germ Human GST tag 2 μg Log in to see 9 Days
$333.33
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   50 μg Log in to see 16 to 21 Days
$314.29
Details

HLA-DPA1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
, ,

More Proteins for Major Histocompatibility Complex, Class II, DP alpha 1 (HLA-DPA1) Interaction Partners

Human Major Histocompatibility Complex, Class II, DP alpha 1 (HLA-DPA1) interaction partners

  1. rs3077 in HLA-DPA1 is a significantly associated SNP associated with chronic hepatitis B virus infection and viral clearance.

  2. This resource provides population estimates of the frequencies of HLA alleles at these eight loci in the three population groups, particularly for HLA-DPA1 and HLA-DPB1 (show HLA-DPB1 Proteins) that were not assayed in HapMap.

  3. DPA1*02:01- DPB1 (show HLA-DPB1 Proteins)*14:01 and DPA1*02:01- DPB1 (show HLA-DPB1 Proteins)*17:01 haplotypes provide considerable protection effect against Posner-Schlossman syndrome.

  4. HLA-DP (show HLA-DPB1 Proteins) gene polymorphisms are strongly associated with chronic hepatitis B virus infection.

  5. The study suggests that HLA-DPA1/B1 loci are candidate susceptibility regions that have some marker single nucleotide polymorphisms for both chronic hepatitis C virus infection and F protein generation in the Han Chinese population.

  6. Single nucleotide polymorphisms rs3077 and rs9277378 in HLA-DPA1 and HLA-DPB1 (show HLA-DPB1 Proteins) are significantly associated with protective effects against chronic hepatitis B.

  7. HLA-DPA1 and DPB1 (show HLA-DPB1 Proteins) allele frequencies and haplotypes of the population of Guadeloupe were most similar to African populations, with characteristic alleles and haplotypes that bespeaks the admixture with other ethnicities.

  8. Crystal structure of the extracellular region of the HLA-DPA1/DPB1 (show HLA-DPB1 Proteins) heterodimer, in complex with the major antigenic peptide from the Japanese cedar pollen allergen.

  9. Data indicate that CD4 (show CD4 Proteins)+ T cell allorecognition of HLA-DP (show HLA-DPB1 Proteins) is significantly affected by DPA1 polymorphism.

  10. Studied three HLA-DP (show HLA-DPB1 Proteins) and IL28B (show IL28B Proteins) SNPs of CHB patients with and without spontaneous HBsAg seroclearance.Haplotype analysis of HLA-DP (show HLA-DPB1 Proteins) polymorphisms showed association with HBsAg seroclearance.

Major Histocompatibility Complex, Class II, DP alpha 1 (HLA-DPA1) Protein Profile

Protein Summary

HLA-DPA1 belongs to the HLA class II alpha chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DPA) and a beta (DPB) chain, both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The alpha chain is approximately 33-35 kDa and its gene contains 5 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and the cytoplasmic tail. Within the DP molecule both the alpha chain and the beta chain contain the polymorphisms specifying the peptide binding specificities, resulting in up to 4 different molecules.

Gene names and symbols associated with HLA-DPA1

  • major histocompatibility complex, class II, DP alpha 1 (HLA-DPA1)
  • DP(W3) protein
  • DP(W4) protein
  • HLA-DP1A protein
  • HLADP protein
  • HLASB protein
  • PLT1 protein

Protein level used designations for HLA-DPA1

HLA class II histocompatibility antigen, DP alpha 1 chain , HLA-SB alpha chain , MHC class II DP3-alpha , MHC class II HLA-DPA1 antigen , MHC class II antigen , Primed lymphocyte test-1

GENE ID SPECIES
3113 Homo sapiens
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