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HLA-DPB belongs to the HLA class II beta chain paralogues. Additionally we are shipping HLA-DPB1 Proteins (6) and many more products for this protein.
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the HLA-DP/DQ clusters contribute independently to HBV infection, and the 3'-UTR (show UTS2R Antibodies) region of HLA-DPB1 represents an important functional region involved in HBV infection
Significant associations between chronic hepatitis B infection and five DPB1 alleles (two susceptibility alleles, DPB1(*) 05:01 and (*) 09:01, and three protective alleles, DPB1(*) 02:01, (*) 04:01, and (*) 04:02) were confirmed in Japanese individuals.
The observed positive association between integrated HIV-1 DNA load and frequency of CD8 (show CD8A Antibodies)(+)DR/DP/DQ(+) cells indicates that a close correlation between HIV persistence and immune activation continues during consistently suppressive therapy.
Our results further confirm that genetic variants in the HLA-DP locus are strongly associated with reduced HBV infection and increased the likelihood of spontaneous viral clearance.
Thyroid autoimmunity is highly prevalent in type 1 diabetes mellitus patients and the risk is modulated by HLA-DRB1 (show HLA-DRB1 Antibodies) and HLA-DPB1 loci.
DQB1*06 and DPB1*13 have roles in modulating vaccine-induced antibody responses to affect HIV-1 acquisition
rs9277535 in HLA-DPB1 is a significantly associated SNP associated with chronic hepatitis B virus infection and viral clearance.
This resource provides population estimates of the frequencies of HLA alleles at these eight loci in the three population groups, particularly for HLA-DPA1 (show HLA-DPA1 Antibodies) and HLA-DPB1 that were not assayed in HapMap.
Cellular misfolded proteins rescued from degradation by MHC class II molecules seem to be involved in autoimmune diseases as a target for autoantibodies. (review)
findings indicate the HLA-DPB1*13:01 and +550 A alleles are significantly associated with cervical squamous cell carcinoma (CSCC (show CYP11A1 Antibodies)) risk in Taiwanese women; in addition, significant increase in CSCC (show CYP11A1 Antibodies) risk was observed for HLA-DPB1*13:01-G and DPB1*02:01-A haplotypes
HLA-DPB belongs to the HLA class II beta chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DPA) and a beta chain (DPB), both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The beta chain is approximately 26-28 kDa and its gene contains 6 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and exon 5 encodes the cytoplasmic tail. Within the DP molecule both the alpha chain and the beta chain contain the polymorphisms specifying the peptide binding specificities, resulting in up to 4 different molecules.
major histocompatibility complex, class II, DP beta 1
, B-L beta minor
, BLB major
, Bl-Beta II protein
, MHC class II B-L beta chain
, MHC class II antigen beta chain
, MHC class II beta 1 domain
, MHC class II beta chain 1
, MHC class II beta chain 2
, major histocompatibility complex class II B
, HLA DP14-beta chain
, HLA class II histocompatibility antigen, DP beta 1 chain
, HLA class II histocompatibility antigen, DP(W4) beta chain
, HLA-DP histocompatibility type, beta-1 subunit
, MHC HLA DPB1
, MHC class II HLA-DP-beta-1
, MHC class II HLA-DRB1
, MHC class II antigen DP beta 1 chain
, MHC class II antigen DPB1
, MHC class II antigen DPbeta1
, beta1 domain MHC class II HLA DPB
, class II HLA beta chain
, major histocompatibility complex class II antigen beta chain