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Major Histocompatibility Complex, Class II, DP beta 1 Proteins (HLA-DPB1)

HLA-DPB belongs to the HLA class II beta chain paralogues. Additionally we are shipping HLA-DPB1 Antibodies (73) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
HLA-DPB1 3115 P04440
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Top HLA-DPB1 Proteins at antibodies-online.com

Showing 5 out of 6 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 49 to 54 Days
$6,041.49
Details
HOST_Escherichia coli (E. coli) Human His tag 50 μg Log in to see 21 to 26 Days
$341.00
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   50 μg Log in to see 16 to 21 Days
$314.29
Details

HLA-DPB1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
, ,

More Proteins for Major Histocompatibility Complex, Class II, DP beta 1 (HLA-DPB1) Interaction Partners

Human Major Histocompatibility Complex, Class II, DP beta 1 (HLA-DPB1) interaction partners

  1. the HLA-DP/DQ clusters contribute independently to HBV infection, and the 3'-UTR region of HLA-DPB1 represents an important functional region involved in HBV infection

  2. Significant associations between chronic hepatitis B infection and five DPB1 alleles (two susceptibility alleles, DPB1(*) 05:01 and (*) 09:01, and three protective alleles, DPB1(*) 02:01, (*) 04:01, and (*) 04:02) were confirmed in Japanese individuals.

  3. The observed positive association between integrated HIV-1 DNA load and frequency of CD8 (show CD8A Proteins)(+)DR/DP/DQ(+) cells indicates that a close correlation between HIV persistence and immune activation continues during consistently suppressive therapy.

  4. Our results further confirm that genetic variants in the HLA-DP locus are strongly associated with reduced HBV infection and increased the likelihood of spontaneous viral clearance.

  5. Thyroid autoimmunity is highly prevalent in type 1 diabetes mellitus patients and the risk is modulated by HLA-DRB1 (show HLA-DRB1 Proteins) and HLA-DPB1 loci.

  6. DQB1*06 and DPB1*13 have roles in modulating vaccine-induced antibody responses to affect HIV-1 acquisition

  7. rs9277535 in HLA-DPB1 is a significantly associated SNP associated with chronic hepatitis B virus infection and viral clearance.

  8. This resource provides population estimates of the frequencies of HLA alleles at these eight loci in the three population groups, particularly for HLA-DPA1 (show HLA-DPA1 Proteins) and HLA-DPB1 that were not assayed in HapMap.

  9. Cellular misfolded proteins rescued from degradation by MHC class II molecules seem to be involved in autoimmune diseases as a target for autoantibodies. (review)

  10. findings indicate the HLA-DPB1*13:01 and +550 A alleles are significantly associated with cervical squamous cell carcinoma (CSCC (show CYP11A1 Proteins)) risk in Taiwanese women; in addition, significant increase in CSCC (show CYP11A1 Proteins) risk was observed for HLA-DPB1*13:01-G and DPB1*02:01-A haplotypes

HLA-DPB1 Protein Profile

Protein Summary

HLA-DPB belongs to the HLA class II beta chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DPA) and a beta chain (DPB), both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The beta chain is approximately 26-28 kDa and its gene contains 6 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and exon 5 encodes the cytoplasmic tail. Within the DP molecule both the alpha chain and the beta chain contain the polymorphisms specifying the peptide binding specificities, resulting in up to 4 different molecules.

Gene names and symbols associated with HLA-DPB1

  • major histocompatibility complex, class II, DP beta 1 (PATR-DPB1)
  • Major histocompatibility complex class II beta chain BLB2, (similar to HLA class II, D beta chain) (BLB2)
  • major histocompatibility complex, class II, DP beta 1 (HLA-DPB1)
  • B-LB protein
  • B-LB2 protein
  • B-LB21 protein
  • BLB1 protein
  • DPB1 protein
  • GSP-BLB1 protein
  • HLA-DP protein
  • HLA-DP1B protein
  • HLA-DPB protein
  • PATR-DPB1 protein

Protein level used designations for HLA-DPB1

major histocompatibility complex, class II, DP beta 1 , B-L beta minor , BLB major , Bl-Beta II protein , MHC class II B-L beta chain , MHC class II antigen beta chain , MHC class II beta 1 domain , MHC class II beta chain 1 , MHC class II beta chain 2 , major histocompatibility complex class II B , HLA DP14-beta chain , HLA class II histocompatibility antigen, DP beta 1 chain , HLA class II histocompatibility antigen, DP(W4) beta chain , HLA-DP histocompatibility type, beta-1 subunit , MHC HLA DPB1 , MHC class II HLA-DP-beta-1 , MHC class II HLA-DRB1 , MHC class II antigen DP beta 1 chain , MHC class II antigen DPB1 , MHC class II antigen DPbeta1 , beta1 domain MHC class II HLA DPB , class II HLA beta chain , major histocompatibility complex class II antigen beta chain

GENE ID SPECIES
462599 Pan troglodytes
693256 Gallus gallus
3115 Homo sapiens
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