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Major Histocompatibility Complex, Class II, DQ alpha 1 (HLADQA1) ELISA Kits

HLA-DQA1 belongs to the HLA class II alpha chain paralogues. Additionally we are shipping Major Histocompatibility Complex, Class II, DQ alpha 1 Antibodies (64) and Major Histocompatibility Complex, Class II, DQ alpha 1 Proteins (4) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Human HLADQA1 HLADQA1 3117 P01909
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More ELISA Kits for Major Histocompatibility Complex, Class II, DQ alpha 1 Interaction Partners

Human Major Histocompatibility Complex, Class II, DQ alpha 1 (HLADQA1) interaction partners

  1. The population of a Portuguese Madeira Island is distinguished by the substantial HLA-DQA1 and HLA-DQB1 (show HLA-DQB1 ELISA Kits) allele diversity.

  2. Patients with Latent Autoimmune Diabetes in Adults (LADA) have higher prevalence of thyroid autoimmune diseases. In patients with LADA similarly to type 1 genotype DQA1*0301 seems to CONFER susceptibility to thyroid autoimmunity, and DQB1*0201 to celiac disease.

  3. Two missense SNPs, rs12722042 and 12722039, in the HLA-DQA1 gene yielded the highest effect sizes (odds ratio [OR] approximately 14; P <0.01) for sex-specific results. The HLA-DQA1 SNPs belong to DQA1*01 and confirmed the previously reported male-specific association with DQA1*01. This finding supports the proposed infection-related etiology in childhood ALL risk for males.

  4. A possible pathogenic link that HLA-DQ2 (show TOR1A ELISA Kits)/DQ8 positivity, in presence of exogenous still unknown stimuli, may favor an immune condition with detrimental effects during early stages of pregnancy.

  5. Genetic polymorphism of the HLADQA1 gene in Recurrent Respiratory Papillomatosis patients in combination with carriage of type 16 human papilloma virus can be used for the prognosis of the severity HLADQA1of this disease.

  6. The Sonora, Mexico HLA-DQ risk heterodimer proportion was 16.1% for HLA-DQ2 and 13.6% for HLA-DQ8, with an HLA-DQ2:HLA-DQ8 ratio of 1.2:1. The DQ8/DQ2 genotype represented a 1:14 risk for type 1 diabetes, whereas the DQ8/DQB1*0201 combination showed a 1:6 risk for celiac disease.

  7. HLA-DQA1*0102 and HLA-DQB1 (show HLA-DQB1 ELISA Kits)*0201 alleles may be involved in the production of anti-beta2-glycoprotein I antibody in recurrent miscarriage patients.

  8. DQA1*0501 had significant negative association with MuSK (show MUSK ELISA Kits) myasthenia gravis.

  9. The observed positive association between integrated HIV-1 DNA load and frequency of CD8 (show CD8A ELISA Kits)(+)DR/DP/DQ(+) cells indicates that a close correlation between HIV persistence and immune activation continues during consistently suppressive therapy.

  10. We found association of three variants in the region harboring genes encoding the class II human leukocyte antigens (HLAs): both located between HLA-DQA1 and HLA-DRB1 (show HLA-DRB1 ELISA Kits)

Major Histocompatibility Complex, Class II, DQ alpha 1 (HLADQA1) Antigen Profile

Antigen Summary

HLA-DQA1 belongs to the HLA class II alpha chain paralogues. The class II molecule is a heterodimer consisting of an alpha (DQA) and a beta chain (DQB), both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B Lymphocytes, dendritic cells, macrophages). The alpha chain is approximately 33-35 kDa. It is encoded by 5 exons\; exon 1 encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, and exon 4 encodes the transmembrane domain and the cytoplasmic tail. Within the DQ molecule both the alpha chain and the beta chain contain the polymorphisms specifying the peptide binding specificities, resulting in up to four different molecules. Typing for these polymorphisms is routinely done for bone marrow transplantation.

Gene names and symbols associated with HLADQA1

  • major histocompatibility complex, class II, DQ alpha 1 (HLA-DQA1) antibody
  • CD antibody
  • CELIAC1 antibody
  • DQ-A1 antibody
  • GSE antibody
  • HLA-DQA antibody

Protein level used designations for HLADQA1

DC-1 alpha chain , DC-alpha , HLA class II histocompatibility antigen, DQ alpha 1 chain , HLA class II histocompatibility antigen, DQ(W3) alpha chain , HLA-DCA , MHC HLA-DQ alpha , MHC class II DQA1 , MHC class II HLA-D alpha glycoprotein , MHC class II HLA-DQ-alpha-1 , MHC class II antigen , MHC class II surface glycoprotein , leucocyte antigen DQA1 , leukocyte antigen alpha chain

3117 Homo sapiens
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