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HLA-C belongs to the HLA class I heavy chain paralogues. Additionally we are shipping Major Histocompatibility Complex Class I C Antibodies (49) and Major Histocompatibility Complex Class I C Kits (8) and many more products for this protein.
Showing 6 out of 33 products:
HLA-C2 and -C1, showed highly significant associations with CRC (show CALR Proteins) development.
Therefore, the results obtained in this study demonstrate the involvement of HLA class I (show MICA Proteins) genes in the susceptibility or resistance to American cutaneous leishmaniasis (ACL (show ACLY Proteins)), with significant association between HLA-C*04 and ACL (show ACLY Proteins) susceptibility.
four amino-acid positions of HLA-B and -C account for most of the associations between ankylosing spondylitis and MHC in the Korean population
HLA-C expressed on HIV-infected cells restricts attack by KIR2DL(+) CD56 (show NCAM1 Proteins)(dim) natural killer (NK) cells
Absence of HLA-C2 for donor KIR2DL1 (show KIR2DL1 Proteins) was associated with higher grade II to IV (HR, 1.4; P = .002) and III to IV acute GVHD (HR, 1.5; P = .01) compared with HLA-C2(+) patients.
The authors have identified a deleterious effect of the KIR2DL3 (show KIR2DL3 Proteins)-HLA-C1 receptor-ligand combination on HIV clinical outcomes in a Thai cohort.
HLA-C -35 C/C allele exerts a favorable effect on the immunological (higher baseline and nadir CD4 (show CD4 Proteins)+ T cell count) and virologic (lower pretreatment HIV viral load) variables.
Preformed anti-HLA-Cw and anti-HLA-DP (show HLA-DPB1 Proteins) donor specific antibodies have deleterious impact in kidney transplantation.
Data suggest regulatory interactions between major histocompatibility antigen HLA-C and killer cell Ig-like receptor (KIR) might promote Graft-versus-Leukemia effects following transplantation.
The study aims to assess the distribution of HLA-A, -B, -Cw and DRB1 alleles in Moroccan patients with ankylosing spondylitis (AS) and to compare the clinical features of AS and the frequencies of HLA-B27 in patients from Morocco.
HLA-C belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. Class I molecules play a central role in the immune system by presenting peptides derived from endoplasmic reticulum lumen. They are expressed in nearly all cells. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the alpha1 and alpha2 domain, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region, and exons 6 and 7 encode the cytoplasmic tail. Polymorphisms within exon 2 and exon 3 are responsible for the peptide binding specificity of each class one molecule. Typing for these polymorphisms is routinely done for bone marrow and kidney transplantation. Over one hundred HLA-C alleles have been described
HLA class I histocompatibility antigen, C alpha chain
, HLA class I histocompatibility antigen, Cw-1 alpha chain
, MHC class I antigen heavy chain HLA-C
, human leukocyte antigen-C alpha chain
, major histocompatibility antigen HLA-C