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Major Histocompatibility Complex Class I C Proteins (HLAC)

HLA-C belongs to the HLA class I heavy chain paralogues. Additionally we are shipping Major Histocompatibility Complex Class I C Antibodies (49) and Major Histocompatibility Complex Class I C Kits (8) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
HLAC 3107 P10321
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Top Major Histocompatibility Complex Class I C Proteins at antibodies-online.com

Showing 6 out of 33 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 49 to 54 Days
$6,041.49
Details
HOST_Escherichia coli (E. coli) Human His tag 50 μg Log in to see 21 to 26 Days
$341.00
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   100 μg Log in to see 3 to 4 Days
$388.93
Details
HOST_Wheat germ Human GST tag   25 μg Log in to see 11 to 12 Days
$552.72
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   50 μg Log in to see 16 to 21 Days
$314.29
Details

HLAC Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
, ,

More Proteins for Major Histocompatibility Complex Class I C (HLAC) Interaction Partners

Human Major Histocompatibility Complex Class I C (HLAC) interaction partners

  1. Recurrent Pregnancy Loss in Women with Killer Cell Immunoglobulin-Like Receptor KIR2DS1 (show KIR2DS1 Proteins) is Associated with an Increased HLA-C2 Allelic Frequency

  2. HLA-C genetic polymorphism is associated with psoriasis.

  3. HLA-C2 and -C1, showed highly significant associations with CRC (show CALR Proteins) development.

  4. Therefore, the results obtained in this study demonstrate the involvement of HLA class I (show MICA Proteins) genes in the susceptibility or resistance to American cutaneous leishmaniasis (ACL (show ACLY Proteins)), with significant association between HLA-C*04 and ACL (show ACLY Proteins) susceptibility.

  5. four amino-acid positions of HLA-B and -C account for most of the associations between ankylosing spondylitis and MHC in the Korean population

  6. HLA-C expressed on HIV-infected cells restricts attack by KIR2DL(+) CD56 (show NCAM1 Proteins)(dim) natural killer (NK) cells

  7. Absence of HLA-C2 for donor KIR2DL1 (show KIR2DL1 Proteins) was associated with higher grade II to IV (HR, 1.4; P = .002) and III to IV acute GVHD (HR, 1.5; P = .01) compared with HLA-C2(+) patients.

  8. The authors have identified a deleterious effect of the KIR2DL3 (show KIR2DL3 Proteins)-HLA-C1 receptor-ligand combination on HIV clinical outcomes in a Thai cohort.

  9. HLA-C -35 C/C allele exerts a favorable effect on the immunological (higher baseline and nadir CD4 (show CD4 Proteins)+ T cell count) and virologic (lower pretreatment HIV viral load) variables.

  10. Preformed anti-HLA-Cw and anti-HLA-DP (show HLA-DPB1 Proteins) donor specific antibodies have deleterious impact in kidney transplantation.

Major Histocompatibility Complex Class I C (HLAC) Protein Profile

Protein Summary

HLA-C belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. Class I molecules play a central role in the immune system by presenting peptides derived from endoplasmic reticulum lumen. They are expressed in nearly all cells. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the alpha1 and alpha2 domain, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region, and exons 6 and 7 encode the cytoplasmic tail. Polymorphisms within exon 2 and exon 3 are responsible for the peptide binding specificity of each class one molecule. Typing for these polymorphisms is routinely done for bone marrow and kidney transplantation. Over one hundred HLA-C alleles have been described

Gene names and symbols associated with HLAC

  • major histocompatibility complex, class I, C (HLA-C)
  • D6S204 protein
  • HLA-JY3 protein
  • HLC-C protein
  • PSORS1 protein

Protein level used designations for HLAC

HLA class I histocompatibility antigen, C alpha chain , HLA class I histocompatibility antigen, Cw-1 alpha chain , MHC class I antigen heavy chain HLA-C , human leukocyte antigen-C alpha chain , major histocompatibility antigen HLA-C

GENE ID SPECIES
3107 Homo sapiens
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