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MKRN2 encodes a probable E3 ubiquitin ligase containing several zinc finger domains, that is a member of the makorin RING zinc-finger protein family. Additionally we are shipping MKRN2 Antibodies (79) and MKRN2 Proteins (9) and many more products for this protein.
Over-expression of MKRN2 in K562 cells increased cell proliferation. Our results indicated possible roles of MKRN2 in normal and malignant hematopoiesis.
MKRN2 and RAF1 (show RAF1 ELISA Kits) are co-expressed in tissues and cell lines
These results collectively suggest that the third C(3)H zinc finger, Cys (show DNAJC5 ELISA Kits)-His motif and C(3)HC(4) RING zinc finger are indispensable for the anti-neurogenic activity of mkrn2.
mkrn2 acts downstream of PI3K and Akt (show AKT1 ELISA Kits) and upstream of GSK-3beta (show GSK3b ELISA Kits)
This gene encodes a probable E3 ubiquitin ligase containing several zinc finger domains, that is a member of the makorin RING zinc-finger protein family. This gene overlaps the v-raf-1 murine leukemia viral oncogene homolog 1 (RAF1) gene in an antisense orientation and may have a co-regulatory function with RAF1. Alternative splicing results in multiple transcript variants.
makorin ring finger protein 2
, makorin, ring finger protein, 2
, probable E3 ubiquitin-protein ligase makorin-2-like
, RING finger protein 62
, makorin RING zinc-finger protein 2
, probable E3 ubiquitin-protein ligase makorin-2
, makorin RING finger protein 2
, Makorin RING zinc-finger protein 2