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Malate dehydrogenase catalyzes the reversible oxidation of malate to oxaloacetate, utilizing the NAD/NADH cofactor system in the citric acid cycle. Additionally we are shipping Malate Dehydrogenase 1, NAD (Soluble) Proteins (25) and Malate Dehydrogenase 1, NAD (Soluble) Kits (11) and many more products for this protein.
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Cow (Bovine) Polyclonal MDH1 Primary Antibody for WB - ABIN2783317
Hillier, Graves, Fulton, Fulton, Pepin, Minx, Wagner-McPherson, Layman, Wylie, Sekhon, Becker, Fewell, Delehaunty, Miner, Nash, Kremitzki, Oddy, Du, Sun, Bradshaw-Cordum, Ali, Carter, Cordes, Harris et al.: Generation and annotation of the DNA sequences of human chromosomes 2 and 4. ... in Nature 2005
Show all 3 Pubmed References
Human Polyclonal MDH1 Primary Antibody for ICC, IF - ABIN4333311
Burr, Costa, Grice, Timms, Lobb, Freisinger, Dodd, Dougan, Lehner, Frezza, Nathan: Mitochondrial Protein Lipoylation and the 2-Oxoglutarate Dehydrogenase Complex Controls HIF1α Stability in Aerobic Conditions. in Cell metabolism 2016
Observations on Mdh1 in both Gpdh (show GPD1 Antibodies) and Adh (show AVP Antibodies) backgrounds demonstrate significant increases in ethanol tolerance with partial reductions (50%) in cytosolic MDH (show MDH Antibodies) activity.
Structural features of the alphaB-crystallin (show CRYAB Antibodies) oligomer when complexed with target proteins under mild stress conditions, i.e., reduction of alpha-lactalbumin (show LALBA Antibodies) at 37 degrees C and malate dehydrogenase (show MDH Antibodies) when heated at 42 degrees C, were investigated.
Both immunofluorescence and immunoelectron microscopy demonstrated cMDH at the plasma membrane of LLC-PK(1) cells.
Data show that in the endogenous readthrough of the human MDH1 stop codon, the stop codon can encode tryptophan and arginine, and is tissue-specific.
Proliferating cells rely on both MDH1 and LDH to replenish cytosolic NAD.
Arginine methylation of MDH1 by CARM1 (show CARM1 Antibodies) regulates cellular redox homeostasis and suppresses glutamine (show GFPT1 Antibodies) metabolism of pancreatic cancer.
adipogenic differentiation may be regulated by the acetylation of MDH1
The MDH1 gene is not the cause of RP28 (show FAM161A Antibodies)-linked autosomal recessive retinitis pigmentosa.
expression of MDH1 is maintained in the adult heart but is not present in levels as high as in the fetus
Malate Dehydrogenase (show ME1 Antibodies) directly regulates the Tumor Suppressor Protein p53 (show TP53 Antibodies)-dependent apoptosis upon glucose deprivation and involved in maintaining cellular metabolic state and further determining cell death.
These findings provide strong evidence that MDH1 plays a critical role in osteoclast differentiation and function via modulation of the intracellular energy status, which might affect AMPK (show PRKAA1 Antibodies) activity and NFATc1 (show NFATC1 Antibodies) expression.
Mor2 is an essential factor for oocyte maturation and embryo development in mouse.
Malate dehydrogenase catalyzes the reversible oxidation of malate to oxaloacetate, utilizing the NAD/NADH cofactor system in the citric acid cycle. The protein encoded by this gene is localized to the cytoplasm and may play pivotal roles in the malate-aspartate shuttle that operates in the metabolic coordination between cytosol and mitochondria. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
, cytoplasmic malate dehydrogenase
, malate dehydrogenase, cytoplasmic
, malate dehydrogenase4
, cytosolic malate dehydrogenase
, diiodophenylpyruvate reductase
, soluble malate dehydrogenase
, malate dehydrogenase, soluble
, Malate dehydrogenase-like enzyme