You are viewing an incomplete version of our website. Please click to reload the website as full version.

Male Germ Cell-Associated Kinase Proteins (MAK)

The product of MAK is a serine/threonine protein kinase related to kinases involved in cell cycle regulation. Additionally we are shipping MAK Antibodies (104) and MAK Kits (7) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
MAK 116904  
MAK 4117 P20794
MAK 25677 P20793
How to order from antibodies-online
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Order online
  • orders@antibodies-online.com

Top MAK Proteins at antibodies-online.com

Showing 5 out of 6 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 2 μg Log in to see 9 Days
$333.33
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$3,796.83
Details
HOST_Baculovirus infected Insect Cells Human GST tag   5 μg Log in to see 10 to 12 Days
$322.08
Details

MAK Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)

Human , ,
,
Rat (Rattus)

More Proteins for Male Germ Cell-Associated Kinase (MAK) Interaction Partners

Mouse (Murine) Male Germ Cell-Associated Kinase (MAK) interaction partners

  1. the expressions of ICK/MAK/MOK proteins in the intestinal tract can be differentially and dynamically regulated, implicating a significant functional diversity within this group of protein kinases.

  2. Cardiomyopathy developed in mice deficient for alpha-kinase 3 (ALPK3)

  3. Results suggest that Mak is essential for the regulation of ciliary length and is required for the long-term survival of photoreceptors.

  4. data show that function of MAK is not essential for spermatogenesis and male fertility.

Human Male Germ Cell-Associated Kinase (MAK) interaction partners

  1. We identified the MAK and DHDDS (show DHDDS Proteins) mutations homozygously in only 2.1% and 0.8%, respectively, of patients of mixed ethnicity, but in 25.7% and 8.6%, respectively, of cases reporting Jewish ancestry

  2. Nonsense and missense mutations in MAK give rise to a non-syndromic recessive RP phenotype without apparent extra-ocular features.

  3. the expressions of ICK/MAK/MOK (show MOK Proteins) proteins in the intestinal tract can be differentially and dynamically regulated, implicating a significant functional diversity within this group of protein kinases.

  4. In glioblastoma cells with deregulated high levels of CCRK (show CDK20 Proteins), its depletion restores cilia through ICK (show ICK Proteins) and an ICK (show ICK Proteins)-related kinase MAK, thereby inhibiting glioblastoma cell proliferation.

  5. these data implicate MAK in both adrogen receptor activation and chromosomal instability, acting in both early and late prostate cancer development.

  6. The patterns of disease expression in the MAK form of arRP showed some resemblance to patterns described in autosomal dominant RP, especially the form caused by RP1 mutations.

  7. Exome sequencing to identify a homozygous Alu insertion in exon 9 of male germ cell-associated kinase (MAK) as the cause of disease in an isolated individual with retinitis pigmentosa.

  8. Exome sequencing combined with this approach identified a homozygous nonsense mutation in male germ cell-associated kinase (MAK) in the single affected member of a consanguineous Turkish family with retinitis pigmentosa.

  9. MAK plays a general role in androgen receptor(AR (show AR Proteins)) function in prostate cancer cells and is likely to be a general coactivator of AR in prostate tissues.

  10. MRK (show ICK Proteins) phosphorylates Scythe (show BAT3 Proteins) at T1080 in vitro as determined by site-directed mutagenesis and mass spectrometry, supporting the consensus and suggesting Scythe (show BAT3 Proteins) as a physiological substrate for MRK (show ICK Proteins).

MAK Protein Profile

Protein Summary

The product of this gene is a serine/threonine protein kinase related to kinases involved in cell cycle regulation. It is expressed almost exclusively in the testis, primarily in germ cells. Studies of the mouse and rat homologs have localized the kinase to the chromosomes during meiosis in spermatogenesis, specifically to the synaptonemal complex that exists while homologous chromosomes are paired. There is, however, a study of the mouse homolog that has identified high levels of expression in developing sensory epithelia so its function may be more generalized. Three transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with MAK

  • male germ cell-associated kinase (MAK)
  • male germ cell-associated kinase (mak)
  • male germ cell-associated kinase (LOC100357745)
  • alpha-kinase 3 (Alpk3)
  • male germ cell-associated kinase (Mak)
  • A930010O05Rik protein
  • AW319487 protein
  • D330016D04 protein
  • dJ417M14.2 protein
  • fj04c02 protein
  • Ick protein
  • MAK protein
  • MGC82717 protein
  • MGC146434 protein
  • Midori protein
  • mKIAA1330 protein
  • RP62 protein
  • wu:fj04c02 protein
  • xmak protein
  • zgc:56603 protein

Protein level used designations for MAK

male germ cell-associated kinase , serine/threonine-protein kinase MAK-like , alpha-protein kinase 3 , myocyte induction differentiation originator , myocytic induction/differentiation originator , male germ cell-associated kinase retinal-enriched isoform , serine/threonine protein kinase MAK , serine/threonine-protein kinase MAK , protein kinase RCK , intestinal cell kinase

GENE ID SPECIES
420859 Gallus gallus
447015 Xenopus laevis
698353 Macaca mulatta
746604 Pan troglodytes
780268 Xenopus (Silurana) tropicalis
100019665 Monodelphis domestica
100051342 Equus caballus
100082794 Ornithorhynchus anatinus
100357745 Oryctolagus cuniculus
100469313 Ailuropoda melanoleuca
100603418 Nomascus leucogenys
116904 Mus musculus
4117 Homo sapiens
478721 Canis lupus familiaris
536048 Bos taurus
25677 Rattus norvegicus
17152 Mus musculus
335339 Danio rerio
Selected quality suppliers for MAK Proteins (MAK)
Did you look for something else?