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MSL3 encodes a nuclear protein that is similar to the product of the Drosophila male-specific lethal-3 gene. Additionally we are shipping MSL3 Proteins (5) and many more products for this protein.
Showing 10 out of 39 products:
Cow (Bovine) Polyclonal MSL3 Primary Antibody for WB - ABIN2778441
Smith, Cayrou, Huang, Lane, Côté, Lucchesi: A human protein complex homologous to the Drosophila MSL complex is responsible for the majority of histone H4 acetylation at lysine 16. in Molecular and cellular biology 2005
Cow (Bovine) Polyclonal MSL3 Primary Antibody for WB - ABIN2778442
Beausoleil, Jedrychowski, Schwartz, Elias, Villén, Li, Cohn, Cantley, Gygi: Large-scale characterization of HeLa cell nuclear phosphoproteins. in Proceedings of the National Academy of Sciences of the United States of America 2004
Human Polyclonal MSL3 Primary Antibody for IF, WB - ABIN524348
Kapoor-Vazirani, Vertino: A dual role for the histone methyltransferase PR-SET7/SETD8 and histone H4 lysine 20 monomethylation in the local regulation of RNA polymerase II pausing. in The Journal of biological chemistry 2014
MSL3 plays an important role in targeting the male specific lethal complex to chromatin in both humans and flies by binding to H4K20Me(1).
A multisubunit human histone acetylase complex that contains homologs of the Drosophila MSL proteins MOF (show KAT8 Antibodies), MSL1 (hampin (show MSL1 Antibodies) A), MSL2 (show MSL2 Antibodies), and MSL3 was described. This complex is responsible for histone H4 lysine-16 acetylation of all cellular chromosomes.
Msl1 interacts with Msl3 as an extended chain forming an extensive hydrophobic interface, whereas the Msl1-MOF interface involves electrostatic interactions between the HAT domain and a long helix of Msl1.
Analysis of Mid1 (show MID1 Antibodies), Hccs (show HCCS Antibodies), Arhgap6 (show ARHGAP6 Antibodies), and Msl3l1 in X-linked polydactyly (Xpl) and Patchy-fur (Paf (show KIAA0101 Antibodies)) mutant mice
This gene encodes a nuclear protein that is similar to the product of the Drosophila male-specific lethal-3 gene. The Drosophila protein plays a critical role in a dosage-compensation pathway, which equalizes X-linked gene expression in males and females. Thus, the human protein is thought to play a similar function in chromatin remodeling and transcriptional regulation, and it has been found as part of a complex that is responsible for histone H4 lysine-16 acetylation. This gene can undergo X inactivation. Alternative splicing results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 2, 7 and 8.
male-specific lethal 3 homolog (Drosophila)
, male-specific lethal 3-like 1
, Male-specific lethal 3-like 1
, MSL3-like 1
, male-specific lethal 3 homolog
, male-specific lethal-3 protein-like 1
, male-specific lethal-3 homolog 1