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anti-Malic Enzyme 1, NADP(+)-Dependent, Cytosolic (ME1) Antibodies

ME1 encodes a cytosolic, NADP-dependent enzyme that generates NADPH for fatty acid biosynthesis. Additionally we are shipping ME1 Proteins (5) and ME1 Kits (2) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
ME1 4199 P48163
ME1 17436 P06801
ME1 24552  
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Top anti-ME1 Antibodies at antibodies-online.com

Showing 10 out of 48 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Chicken Rabbit Un-conjugated WB WB Suggested Anti-ME1 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:312500Positive Control: HepG2 cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated ELISA, WB Western blot analysis of extracts from HeLa cells, using ME1 Antibody. The lane on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Mouse Un-conjugated WB Western Blot analysis of ME1 expression in transfected 293T cell line by ME1 monoclonal antibody (M03), clone 3H5. Lane 1: ME1 transfected lysate(64.1 KDa). Lane 2: Non-transfected lysate. ME1 monoclonal antibody (M03), clone 3H5. Western Blot analysis of ME1 expression in HepG2. 0.1 mg Log in to see 8 to 11 Days
$450.00
Details
Human Mouse Un-conjugated ELISA, WB Detection limit for recombinant GST tagged ME1 is approximately 3 ng/mL as a capture antibody. 0.1 mg Log in to see 8 to 11 Days
$450.00
Details
Human Mouse Un-conjugated IHC (p), ELISA, WB ME1 monoclonal antibody (M03), clone 3H5. Western Blot analysis of ME1 expression in HepG2 . Immunoperoxidase of monoclonal antibody to ME1 on formalin-fixed paraffin-embedded human tonsil. [antibody concentration 0.5 ug/ml] 100 μg Log in to see 9 Days
$430.00
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Rabbit Un-conjugated ICC, IF, IP, IHC (p), WB IHC-P Image ME1 antibody detects ME1 protein at cytosol on human ovarian carcinoma by immunohistochemical analysis. Sample: Paraffin-embedded human ovarian carcinoma. ME1 antibody , dilution: 1:500. WB Image Sample (30 ug of whole cell lysate) A: NIH-3T3 B: JC C: BCL-1 7.5% SDS PAGE antibody diluted at 1:1000 100 μL Log in to see 2 to 3 Days
$358.60
Details
Human Rabbit Un-conjugated WB Western blot (WB) analysis of Malic enzyme 1 antibody in extracts from HeLa cells. 0.1 mg Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated ELISA, WB 50 μg Log in to see 2 to 3 Days
$433.13
Details
Human Rabbit Un-conjugated ELISA, WB 100 μL Log in to see 8 to 10 Days
$478.50
Details

ME1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
Human ,
,
,
Mouse (Murine)


Rat (Rattus)


Top referenced anti-ME1 Antibodies

  1. Human Monoclonal ME1 Primary Antibody for ELISA, WB - ABIN395837 : Hsieh, Su, Ho, Hung: Long-range interaction between the enzyme active site and a distant allosteric site in the human mitochondrial NAD(P)+-dependent malic enzyme. in Archives of biochemistry and biophysics 2009 (PubMed)
    Show all 5 references for ABIN395837

  2. Human Monoclonal ME1 Primary Antibody for WB - ABIN396141 : Hsieh, Chen, Hung: Functional roles of the tetramer organization of malic enzyme. in The Journal of biological chemistry 2009 (PubMed)
    Show all 5 references for ABIN396141

  3. Chicken Polyclonal ME1 Primary Antibody for WB - ABIN2777597 : Hsieh, Liu, Chang, Hung: Determinants of the dual cofactor specificity and substrate cooperativity of the human mitochondrial NAD(P)+-dependent malic enzyme: functional roles of glutamine 362. in The Journal of biological chemistry 2006 (PubMed)

  4. Human Monoclonal ME1 Primary Antibody for IHC (p), ELISA - ABIN561774 : Heart, Cline, Collis, Pongratz, Gray, Smith: Role for malic enzyme, pyruvate carboxylation, and mitochondrial malate import in glucose-stimulated insulin secretion. in American journal of physiology. Endocrinology and metabolism 2009 (PubMed)

  5. Human Polyclonal ME1 Primary Antibody for ELISA, WB - ABIN1535074 : González-Manchón, Ferrer, Ayuso, Parrilla: Cloning, sequencing and functional expression of a cDNA encoding a NADP-dependent malic enzyme from human liver. in Gene 1995 (PubMed)

More Antibodies against ME1 Interaction Partners

Human Malic Enzyme 1, NADP(+)-Dependent, Cytosolic (ME1) interaction partners

  1. ME1 expression was found to be mutant-KRAS-associated in NSCLC cancer cell lines. Patients with elevated ME1 had worse outcomes after radiotherapy. Transamination generating cytosolic NADPH via ME1 may contribute to radioresistance.

  2. ME1 overexpression associates with unfavorable prognoses in patients with HCC (show FAM126A Antibodies), suggesting that ME1 is a poor prognostic predictor of hepatocellular carcinoma.

  3. essential role for ME1 in the production of cytosolic NADPH (show NQO1 Antibodies) and maintenance of migratory and invasive abilities of nasopharyngeal carcinoma cells

  4. the differential protein stability between dimer and tetramer interface interactions of human c-NADP-ME

  5. p53 (show TP53 Antibodies) represses the expression of the tricarboxylic-acid-cycle-associated malic enzymes ME1 and ME2 (show CELSR1 Antibodies) in human and mouse cells

  6. cytosolic malic enzyme 1 gene polymorphism is associated with the degree of suppression of parathyroid hormone (show PTH Antibodies) after long-term calcium supplementation; the effect is probably mediated through an increase in intestinal calcium absorption

  7. ME1 is a functional target gene of the BACH1 (show BACH1 Antibodies) transcription factor according to ChIP-seq and knockdown analysis in HEK (show EPHA3 Antibodies) 293 cells.

  8. that the single mutation of Gln362 to Lys in human m-NAD-ME changes it to an NADP+-dependent enzyme, which is characteristic because it is non-allosteric, non-cooperative, and NADP+-specific

  9. although ME1 overexpression augments anaplerosis and glucose stimulated insulin (show INS Antibodies) secretion in INS-1 (show FOXM1 Antibodies) 832/13 cells, it is not likely involved in methyl succinate and glucose stimulated insulin (show INS Antibodies) secretion in pancreatic islets

  10. human c-NADP-ME exists mainly as a tetramer, whereas human m-NAD(P)-ME exists as a mixture of dimers and tetramers

Pig (Porcine) Malic Enzyme 1, NADP(+)-Dependent, Cytosolic (ME1) interaction partners

  1. This lack of consistency across families, combined with the fact that the ME1 mutation is synonymous and that the two DECR1 (show DECR1 Antibodies) polymorphisms are conservative, suggests that the associations found are not causative.

  2. Transcript level of the porcine ME1 gene is affected by SNP in its 3'UTR (show UTS2R Antibodies), which is also associated with subcutaneous fat thickness.

  3. Malic enzyme 1 genotype is associated with backfat thickness and meat quality traits in pigs.

Cow (Bovine) Malic Enzyme 1, NADP(+)-Dependent, Cytosolic (ME1) interaction partners

  1. Six novel SNPs, five in ME1 and one in NR0B2 (show NR0B2 Antibodies), were identified as candidates that have effects on meat and carcass quality traits.

  2. ME1-Dra I genotypes had a significant effect on cooking loss.

Mouse (Murine) Malic Enzyme 1, NADP(+)-Dependent, Cytosolic (ME1) interaction partners

  1. This study showed that (2)H-labeled tracers enable dissection of NADPH (show FDXR Antibodies) production routes across cell types and environmental conditions.

  2. ME1 expression was found to be mutant-KRAS-associated in an NSCLC mouse model.

  3. HEB (show FREM1 Antibodies) is a fundamental link between Nodal signalling, the derepression of a specific class of poised promoters during differentiation, and lineage specification in mouse embryonic stem cells

  4. severe bilateral coronal synostosis occurs in mice with 50% of the wild-type dosage of both the Tcf12 (show TCF12 Antibodies) and Twist1 (show TWIST1 Antibodies) genes highlights the key role of TCF12 (show TCF12 Antibodies) acting with TWIST1 (show TWIST1 Antibodies) in the normal development of the coronal sutures

  5. p53 (show TP53 Antibodies) represses the expression of the tricarboxylic-acid-cycle-associated malic enzymes ME1 and ME2 (show TCF4 Antibodies) in human and mouse cells

  6. Deficiency in the E proteins, E2A (show TCF3 Antibodies) and HEB (show FREM1 Antibodies), led to increased frequency of terminally differentiated effector KLRG1 (show KLRG1 Antibodies)(hi) CD8 (show CD8A Antibodies)(+) T cells in mice during infection, and decreased generation of longer-lived memory-precursor cells during the immune response.

  7. Deletion of HEB (show FREM1 Antibodies) and E2A (show TCF3 Antibodies) in DP thymocytes specifically blocked the development of CD4 (show CD4 Antibodies)(+) lineage T cells. Furthermore, deletion of the E protein inhibitors Id2 and Id3 (show ID3 Antibodies) allowed CD4 (show CD4 Antibodies)(+) T cell development but blocked CD8 (show CD8A Antibodies)(+) lineage development.

  8. the earliest event in B-cell specification involves the induction of FOXO1 (show FOXO1 Antibodies) expression and requires the combined activities of E2A (show TCF3 Antibodies) and HEB (show FREM1 Antibodies)

  9. These results showed a new set of interactions between HEB (show FREM1 Antibodies), Notch1 (show NOTCH1 Antibodies), and GATA3 (show GATA3 Antibodies) that regulate the T-cell fate choice in developing thymocytes.

  10. Developmental progression of fetal HEB (show FREM1 Antibodies)(-/-) precursors to the pre-T-cell stage is restored by HEBAlt.

ME1 Antigen Profile

Protein Summary

This gene encodes a cytosolic, NADP-dependent enzyme that generates NADPH for fatty acid biosynthesis. The activity of this enzyme, the reversible oxidative decarboxylation of malate, links the glycolytic and citric acid cycles. The regulation of expression for this gene is complex. Increased expression can result from elevated levels of thyroid hormones or by higher proportions of carbohydrates in the diet.

Gene names and symbols associated with ME1

  • malic enzyme 1, NADP(+)-dependent, cytosolic (ME1) antibody
  • malic enzyme 1, NADP(+)-dependent, cytosolic (me1) antibody
  • malic enzyme 1, NADP(+)-dependent, cytosolic (Me1) antibody
  • transcription factor 12 (Tcf12) antibody
  • A130037E08Rik antibody
  • ALF1 antibody
  • bHLHb20 antibody
  • D9Ertd267e antibody
  • HEB antibody
  • HEBAlt antibody
  • HTF-4 antibody
  • HTF4 antibody
  • HUMNDME antibody
  • Mdh-1 antibody
  • ME1 antibody
  • MES antibody
  • Mod-1 antibody
  • MOD1 antibody
  • REB antibody
  • zgc:153079 antibody

Protein level used designations for ME1

NADP-dependent malic enzyme , cytosolic malic enzyme 1 , malic enzyme 1, NADP(+)-dependent, cytosolic , cytosolic malic enzyme 1-like , NADP-dependent malic enzyme-like , Malic enzyme, cytoplasmic , NADP-ME , malate dehydrogenase , malic enzyme 1, soluble , pyruvic-malic carboxylase , malate dehydrogenase decarboxylase (NADP+) , malic enzyme 1, NADP(+)-dependent, cytoplasmic (cytosolic, soluble) , malic enzyme, supernatant , malate dehydrogenase (oxaloacetate-decarboxylating) (NADP+) , DNA-binding protein HTF4 , E-box-binding protein , TCF-12 , class A helix-loop-helix transcription factor ME1 , transcription factor HTF-4

GENE ID SPECIES
100070127 Equus caballus
100189620 Ovis aries
462853 Pan troglodytes
694739 Macaca mulatta
768196 Danio rerio
100024530 Monodelphis domestica
100125332 Meleagris gallopavo
100145399 Xenopus (Silurana) tropicalis
100355457 Oryctolagus cuniculus
100367220 Saccoglossus kowalevskii
100407892 Callithrix jacchus
100601685 Nomascus leucogenys
374189 Gallus gallus
4199 Homo sapiens
397538 Sus scrofa
540985 Bos taurus
17436 Mus musculus
24552 Rattus norvegicus
403709 Canis lupus familiaris
21406 Mus musculus
Selected quality suppliers for anti-ME1 (ME1) Antibodies
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