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Malignant T Cell Amplified Sequence 1 Proteins (MCTS1)

The protein encoded by MCTS1 is a proton-linked monocarboxylate transporter that catalyzes the movement of many monocarboxylates, such as lactate and pyruvate, across the plasma membrane. Additionally we are shipping Malignant T Cell Amplified Sequence 1 Antibodies (79) and Malignant T Cell Amplified Sequence 1 Kits (6) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
MCTS1 17236  
MCTS1 28985 Q9ULC4
MCTS1 302500 Q4G009
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Top Malignant T Cell Amplified Sequence 1 Proteins at antibodies-online.com

Showing 10 out of 13 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag 100 μg Log in to see 7 to 8 Days
$319.00
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Escherichia coli (E. coli) Human His-SUMO Tag   50 μg Log in to see 11 Days
$341.00
Details
Yeast Cow His tag   1 mg Log in to see 56 to 66 Days
$2,427.33
Details
Yeast Zebrafish His tag   1 mg Log in to see 56 to 66 Days
$2,427.33
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$2,429.17
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   100 μg Log in to see 3 to 4 Days
$382.86
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 19 Days
$785.40
Details

MCTS1 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)

Human , ,
, ,
Rat (Rattus)

Top referenced Malignant T Cell Amplified Sequence 1 Proteins

  1. Human MCTS1 Protein expressed in Escherichia coli (E. coli) - ABIN1098561 : Herbert, Shi, Gartenhaus: Expression and stabilization of the MCT-1 protein by DNA damaging agents. in Oncogene 2001 (PubMed)
    Show all 2 references for ABIN1098561

More Proteins for Malignant T Cell Amplified Sequence 1 (MCTS1) Interaction Partners

Mouse (Murine) Malignant T Cell Amplified Sequence 1 (MCTS1) interaction partners

  1. MCT1 inhibition impairs proliferation of glycolytic breast cancer cells co-expressing MCT1 and MCT4 (show SLC16A3 Proteins) via disruption of pyruvate rather than lactate export.

  2. This study demonstrated that MCT1 was up regulation in ipsilateral site of brain afeter cerebral ischemia.

  3. The soleus, liver and heart were the main tissues that showed improved the MCT1 mRNA expression, indicating its important role in controlling MLSS concentration in mice.

  4. Exercise-induced changes in tumour LDH-B (show LDHB Proteins) and MCT1 expression are modulated by oestrogen-related receptor alpha in breast cancer-bearing BALB/c mice

  5. Chronic lactate administration after exercise increases MCT1 protein expression, which can be involved in the regulation of the observed increase in muscle glycogen (show GYS1 Proteins) storage after exercise training.

  6. This study showed that mouse MCT1, MCT2, and MCT4 (show SLC16A3 Proteins) are expressed in the PNS. While DRG neurons express MCT1, myelinating Schwann cells.

  7. These data for the first time demonstrate that MCT1 is critical for regeneration of both sensory and motor axons in mice following sciatic nerve crush

  8. Study demonstrated that PTEN loss and MCT-1 induction synergistically promoted the neoplastic multinucleation via the Src/p190B signaling activation.

  9. in Parkinson's disease, the levels of MCT1, MCT2 and GLUT1 (show SLC2A1 Proteins) is not changed following dopaminergic neurodegeneration

  10. results suggest that a reduction in mitochondria is a result, rather than the cause, of the metabolic deficiency observed in Basigin (show BSG Proteins)-null mice, and likely occurs because of reduced metabolic activity in the absence of MCT1 expression.

Human Malignant T Cell Amplified Sequence 1 (MCTS1) interaction partners

  1. MCT1 (show CMA1 Proteins) expression associates with the SCC (show CYP11A1 Proteins) type and metastatic behavior of AC, whereas MCT4 (show SLC16A4 Proteins) expression concomitantly increases from in situ SCC (show CYP11A1 Proteins) to invasive SCC (show CYP11A1 Proteins) and is significantly associated with the AC type. Consistently, FOXM1 (show FOXM1 Proteins) expression is statistically associated with MCT1 (show CMA1 Proteins) positivity in SCC (show CYP11A1 Proteins), whereas the expression of FOXO3a (show FOXO3 Proteins), a FOXM1 (show FOXM1 Proteins) functional antagonist, is linked to MCT1 (show CMA1 Proteins) negativity

  2. This study investigated MCT1 (show CMA1 Proteins) protein abundance in various human intestinal tissues.

  3. MCT1 (show CMA1 Proteins) affects the plasma lactate decrease .

  4. The aim of this study was to investigate the association between the MCT1 (show CMA1 Proteins) A1470T polymorphism and fat-free (show VPS51 Proteins) mass in young Italian elite soccer players. The MCT1 (show CMA1 Proteins) T allele is associated with the percentage of fat-free (show VPS51 Proteins) mass in young elite male soccer players.

  5. MCT1 (show CMA1 Proteins) inhibition impairs proliferation of glycolytic breast cancer cells co-expressing MCT1 (show CMA1 Proteins) and MCT4 (show SLC16A4 Proteins) via disruption of pyruvate rather than lactate export.

  6. MCT1 (show CMA1 Proteins) expression was not clearly associated with overall or disease-free survival. MCT4 (show SLC16A4 Proteins) and CD147 (show BSG Proteins) expression correlate with worse prognosis across many cancer types. These results warrant further investigation of these associations.

  7. MCT1 (show CMA1 Proteins) and GLUT1 (show SLC2A1 Proteins) may be potential prognostic markers in adenocarcinoma.

  8. MCT1 (show CMA1 Proteins) is highly expressed in anaplastic thyroid cancer compared to non-cancerous thyroid tissue and papillary thyroid cancer.

  9. interaction of rmEMMPRINex with U937 cells leads to inhibition of MCT1 (show CMA1 Proteins) membrane expression, intracellular activation of procaspase-9, followed by DNA fragmentation and apoptosis.

  10. Down regulation of MCT1 (show CMA1 Proteins) promote the sensitivity to cisplatin in ovarian cancer cells. This effect appeared to be mediated by antagonizing Fas (show FAS Proteins).

Zebrafish Malignant T Cell Amplified Sequence 1 (MCTS1) interaction partners

  1. Data indicate that monocarboxylate transporters (MCTs1-4) were all found to be expressed in brains of embryos, and were localized in both neurons and astrocyte.

Cow (Bovine) Malignant T Cell Amplified Sequence 1 (MCTS1) interaction partners

  1. This study confirmed age-dependent changes of MCT1 expression in the rumen epithelium of newborn calves and showed that its expression might be affected by liquid feed type.

  2. These findings show that MCT 1 increases with the development of rumen function and also in adult animals MCT 1 may change with the feeding.

  3. The expression and distribution of monocarboxylate transporter 1 along the gastrointestinal tract of calves suggest it may play a role in transport of short chain fatty acids and their metabolites.

  4. The results show that monocarboxylate transporter 1 (MCT1) is a major route for short chain fatty acids (SCFA) efflux across the basolateral membrane of bovine large intestine and that it could play a role in the regulation of intracellular pH.

Pig (Porcine) Malignant T Cell Amplified Sequence 1 (MCTS1) interaction partners

  1. Data suggest that expression of MCT1 in intestinal mucosa can be altered by diet; here, expression of MCT1 is down-regulated in colonic mucosa by high-protein diet and appears to be linked to fermentation of dietary proteins by intestinal microbes.

  2. MCT1-mRNA showed a higher expression in the ileum; feeding inulin-coated butyrate resulted in an increased ileal surface; delivery of butyrate to the colon requires a more resistant inulin-coating.

Malignant T Cell Amplified Sequence 1 (MCTS1) Protein Profile

Protein Summary

The protein encoded by this gene is a proton-linked monocarboxylate transporter that catalyzes the movement of many monocarboxylates, such as lactate and pyruvate, across the plasma membrane. Mutations in this gene are associated with erythrocyte lactate transporter defect. Alternatively spliced transcript variants have been found for this gene.

Gene names and symbols associated with MCTS1

  • modifier of curly tail 1 (mct1)
  • malignant T cell amplified sequence 1 (TEgg094c21.2)
  • malignant T cell amplified sequence 1 (MCTS1)
  • malignant T cell amplified sequence 1 (mcts1)
  • malignant T cell amplified sequence 1 (Mcts1)
  • malignant T cell amplified sequence 1 (mcts1-a)
  • monocarboxylate transporter 1 (MCT1)
  • solute carrier family 16 (monocarboxylate transporter), member 1 (SLC16A1)
  • solute carrier family 16 (monocarboxylate transporter), member 1 (Slc16a1)
  • solute carrier family 16 (monocarboxylic acid transporters), member 1 (Slc16a1)
  • solute carrier family 16 (monocarboxylic acid transporters), member 1 (slc16a1)
  • solute carrier family 16, member 1 (monocarboxylic acid transporter 1) (SLC16A1)
  • 1500019M23Rik protein
  • AL022710 protein
  • cb517 protein
  • HHF7 protein
  • MCT protein
  • mct-1 protein
  • MCT-1A protein
  • Mct1 protein
  • MCT1a protein
  • MCTS1 protein
  • MGC89874 protein
  • RATMCT1 protein
  • RNMCT1 protein
  • zgc:55682 protein
  • zgc:56242 protein

Protein level used designations for MCTS1

malignant T cell amplified sequence 1 , malignant T cell-amplified sequence 1 , malignant T-cell-amplified sequence 1 , multiple copies T-cell malignancies , multiple copies T-cell malignancies 1 , MCT-1 , Malignant T cell amplified sequence 1-A , malignant T cell-amplified sequence 1-A , malignant T-cell-amplified sequence 1-A , MCT 1 , monocarboxylate transporter 1 , solute carrier family 16 (monocarboxylic acid transporters), member 1 , solute carrier family 16 member 1 , solute carrier family 16, member 1 (monocarboxylic acid transporter 1) , solute carrier 16 (monocarboxylic acid transporter), member 1 , MCT1 , monocarboxylate transporter 1a

GENE ID SPECIES
17236 Mus musculus
448679 Xenopus (Silurana) tropicalis
465836 Pan troglodytes
696543 Macaca mulatta
100528791 Ictalurus punctatus
28985 Homo sapiens
68995 Mus musculus
394046 Danio rerio
503679 Xenopus laevis
422363 Gallus gallus
481038 Canis lupus familiaris
508412 Bos taurus
302500 Rattus norvegicus
780423 Sus scrofa
6566 Homo sapiens
25027 Rattus norvegicus
20501 Mus musculus
368274 Danio rerio
475856 Canis lupus familiaris
505775 Bos taurus
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