anti-Malignant T Cell Amplified Sequence 1 (MCTS1) Antibodies

The protein encoded by MCTS1 is a proton-linked monocarboxylate transporter that catalyzes the movement of many monocarboxylates, such as lactate and pyruvate, across the plasma membrane. Additionally we are shipping Malignant T Cell Amplified Sequence 1 Proteins (10) and Malignant T Cell Amplified Sequence 1 Kits (9) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
MCTS1 28985 Q9ULC4
MCTS1 68995 Q9DB27
MCTS1 302500 Q4G009
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Top anti-Malignant T Cell Amplified Sequence 1 Antibodies at antibodies-online.com

Showing 10 out of 85 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB <b>WB Suggested Anti-MCTS1 Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:312500<br><b>Positive Control: </b>COLO205 cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated EIA, WB Western blot analysis of MCT-1 antibody (N-term) in mouse bladder tissue lysates (35ug/lane). MCTS1 (arrow) was detected using the purified Pab. 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated WB Western Blot: MCT1 Antibody [ABIN152954] - WB detection of MCT1 in lysate of transfected HEK 293T cells using ABIN152954 antibody at a dilution of 1:500. 0.1 mL Log in to see 7 to 9 Days
$317.63
Details
Human Rabbit Un-conjugated WB Western Blot: MCTS1 Antibody [NBP1-58236] - COLO205 cells lysate, concentration 0.2-1 ug/ml. 100 μL Log in to see 8 to 11 Days
$447.56
Details
Human Rabbit Un-conjugated WB Western blot analysis of MCT-1 antibody (N-term) (ABIN390599) in mouse bladder tissue lysates (35 µg/lane). MCTS1 (arrow) was detected using the purified polyclonal antibody. Formalin-fixed and paraffin-embedded human lymphoma reacted with MCT-1 Antibody (N-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Chicken Rabbit Un-conjugated IHC (p), ELISA, WB Human Prostate (formalin-fixed, paraffin-embedded) stained with MCTS1 antibody ABIN214274 at 20 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. 50 μg Log in to see 7 to 9 Days
$451.00
Details
Human Mouse Un-conjugated IHC, WB HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY MCTS1 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with anti-MCTS1. Immunohistochemical staining of paraffin-embedded Human colon tissue using anti-MCTS1 mouse monoclonal antibody. (ABIN2454240) 100 μL Log in to see 2 to 3 Days
$482.90
Details
Human Rabbit Un-conjugated IHC, IHC (p), WB Western Blot: MCT1 Antibody [NBP2-17242] - Sample (30 ug of whole cell lysate) A: Jurkat 12% SDS PAGE gel, diluted at 1:1000. Western Blot: MCTS1 Antibody  diluted at 1:500. The HRP-conjugated anti-rabbit IgG antibody (NBP2-19301) was used to detect the primary antibody. 0.1 mL Log in to see 8 to 11 Days
$447.56
Details
Human Mouse Un-conjugated IHC (p), WB 100 μL Log in to see 7 to 9 Days
$493.17
Details
Human Goat Un-conjugated ELISA, WB   100 μg Log in to see 6 to 7 Days
$326.89
Details

MCTS1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-Malignant T Cell Amplified Sequence 1 Antibodies

  1. Mouse (Murine) Polyclonal MCTS1 Primary Antibody for IHC - ABIN966547 : Carpenter, Poole, Halestrap: Cloning and sequencing of the monocarboxylate transporter from mouse Ehrlich Lettré tumour cell confirms its identity as MCT1 and demonstrates that glycosylation is not required for MCT1 function. in Biochimica et biophysica acta 1996 (PubMed)
    Show all 6 Pubmed References

  2. Human Polyclonal MCTS1 Primary Antibody for WB - ABIN4891880 : Haas, Ngo, Li, Schleich, Qu, Vanyai, Cullen, Cardona-Alberich, Gladwyn-Ng, Pagnamenta, Taylor, Stewart, Kini, Duncan, Teleman, Keays, Heng: De Novo Mutations in DENR Disrupt Neuronal Development and Link Congenital Neurological Disorders to Faulty mRNA Translation Re-initiation. in Cell reports 2016 (PubMed)

  3. Human Polyclonal MCTS1 Primary Antibody for WB - ABIN152954 : Kumar, Kant, Singh et al.: Antitumor and chemosensitizing action of dichloroacetate implicates modulation of tumor microenvironment: a role of reorganized glucose metabolism, cell survival regulation and macrophage ... in Toxicology and applied pharmacology 2013 (PubMed)

More Antibodies against Malignant T Cell Amplified Sequence 1 Interaction Partners

Mouse (Murine) Malignant T Cell Amplified Sequence 1 (MCTS1) interaction partners

  1. Silencing or genetic deletion of MCT1 in vivo inhibited migration, invasion, and spontaneous metastasis.

  2. It was concluded that both MCT1 and CAII (show CA2 Antibodies) are involved in the homeostatic control of pH in skeletal muscle, both at rest and at the onset of exercise. The improved muscle function and resistance to fatigue in MCT1(+/-) mice remain unexplained.

  3. MCT1 inhibition impairs proliferation of glycolytic breast cancer cells co-expressing MCT1 and MCT4 (show SLC16A3 Antibodies) via disruption of pyruvate rather than lactate export.

  4. This study demonstrated that MCT1 was up regulation in ipsilateral site of brain afeter cerebral ischemia.

  5. The soleus, liver and heart were the main tissues that showed improved the MCT1 mRNA expression, indicating its important role in controlling MLSS concentration in mice.

  6. Exercise-induced changes in tumour LDH-B (show LDHB Antibodies) and MCT1 expression are modulated by oestrogen-related receptor alpha in breast cancer-bearing BALB/c mice

  7. Chronic lactate administration after exercise increases MCT1 protein expression, which can be involved in the regulation of the observed increase in muscle glycogen (show GYS1 Antibodies) storage after exercise training.

  8. This study showed that mouse MCT1, MCT2 (show SLC16A7 Antibodies), and MCT4 (show SLC16A3 Antibodies) are expressed in the PNS. While DRG neurons express MCT1, myelinating Schwann cells.

  9. These data for the first time demonstrate that MCT1 is critical for regeneration of both sensory and motor axons in mice following sciatic nerve crush

  10. Study demonstrated that PTEN (show PTEN Antibodies) loss and MCT-1 induction synergistically promoted the neoplastic multinucleation via the Src (show SRC Antibodies)/p190B (show ARHGAP5 Antibodies) signaling activation.

Human Malignant T Cell Amplified Sequence 1 (MCTS1) interaction partners

  1. MCT1 (show CMA1 Antibodies) inhibitor AZD3965 increased MCT4 (show SLC16A4 Antibodies)-dependent accumulation of intracellular lactate, inhibiting monocarboxylate influx and efflux.

  2. Silencing or genetic deletion of MCT1 (show CMA1 Antibodies) in vivo inhibited migration, invasion, and spontaneous metastasis.

  3. The reversible H(+)/lactate(-) symporter MCT1 (show CMA1 Antibodies) cotransports lactate and proton, leading to the net extrusion of lactic acid in glycolytic tumors. A model of its role in pH control in tumor cells is described. Review.

  4. Reinitiation complexes involving initiation factors eIF2D (show EIF2D Antibodies), MCT-1 (show CMA1 Antibodies), and DENR (show DENR Antibodies) controls the translation of a large fraction of mammalian cellular mRNAs.

  5. Increased miR (show MLXIP Antibodies)-210 and concomitant decreased ISCU (show ISCU Antibodies) RNA levels were found in ~40% of tumors and this was significantly associated with HIF-1alpha (show HIF1A Antibodies) and CAIX (show CA9 Antibodies), but not MCT1 (show CMA1 Antibodies) or MCT4 (show SLC16A4 Antibodies), over-expression.

  6. Data show that metastasis-associated in colon cancer-1 (MACC1 (show MACC1 Antibodies)) and monocarboxylate transporter 1 (MCT1) are highly expressed in gastric cancer indicating poor prognosis.

  7. AA genotype of the MCT1 (show CMA1 Antibodies) T1470A polymorphism is over-represented in wrestlers compared with controls and is associated with lower blood lactate concentrations after 30-s Wingate Anaerobic test and during intermittent sprint tests in Japanese wrestlers

  8. MCT1 (show CMA1 Antibodies) and MCT4 (show SLC16A4 Antibodies) expression levels were associated with worse prognosis and shorter overall survival.

  9. MCT1 (show CMA1 Antibodies) may be acting as an uptake transporter and MCT4 (show SLC16A4 Antibodies) as an efflux system across the basolateral membrane for ferulic acid, and that this process is stimulated by butyric acid.

  10. After indirect co-culture, OP was increased in the BxPc-3 and Panc-1 cells; correspondingly, succinate dehydrogenase (show SDHA Antibodies), FH and MCT (show MCAT Antibodies) expression were increased. After the MCT1 (show CMA1 Antibodies)-specific inhibitor removed 'tumor-stromal' metabolic coupling, the migration and invasion abilities of the pancreatic cancer cells were decreased.

Zebrafish Malignant T Cell Amplified Sequence 1 (MCTS1) interaction partners

  1. Data indicate that monocarboxylate transporters (MCTs1-4) were all found to be expressed in brains of embryos, and were localized in both neurons and astrocyte.

Cow (Bovine) Malignant T Cell Amplified Sequence 1 (MCTS1) interaction partners

  1. This study confirmed age-dependent changes of MCT1 expression in the rumen epithelium of newborn calves and showed that its expression might be affected by liquid feed type.

  2. These findings show that MCT 1 increases with the development of rumen function and also in adult animals MCT 1 may change with the feeding.

  3. The expression and distribution of monocarboxylate transporter 1 along the gastrointestinal tract of calves suggest it may play a role in transport of short chain fatty acids and their metabolites.

  4. The results show that monocarboxylate transporter 1 (MCT1) is a major route for short chain fatty acids (SCFA) efflux across the basolateral membrane of bovine large intestine and that it could play a role in the regulation of intracellular pH.

Pig (Porcine) Malignant T Cell Amplified Sequence 1 (MCTS1) interaction partners

  1. Data suggest that expression of MCT1 in intestinal mucosa can be altered by diet; here, expression of MCT1 is down-regulated in colonic mucosa by high-protein diet and appears to be linked to fermentation of dietary proteins by intestinal microbes.

  2. MCT1-mRNA showed a higher expression in the ileum; feeding inulin-coated butyrate resulted in an increased ileal surface; delivery of butyrate to the colon requires a more resistant inulin-coating.

Malignant T Cell Amplified Sequence 1 (MCTS1) Antigen Profile

Protein Summary

The protein encoded by this gene is a proton-linked monocarboxylate transporter that catalyzes the movement of many monocarboxylates, such as lactate and pyruvate, across the plasma membrane. Mutations in this gene are associated with erythrocyte lactate transporter defect. Alternatively spliced transcript variants have been found for this gene.

Gene names and symbols associated with MCTS1

  • MCTS1, re-initiation and release factor (MCTS1) antibody
  • malignant T cell amplified sequence 1 (Mcts1) antibody
  • MCTS1, re-initiation and release factor (Mcts1) antibody
  • malignant T cell amplified sequence 1 (mcts1) antibody
  • malignant T-cell amplified sequence 1 (mcts1) antibody
  • MCTS1, re-initiation and release factor (mcts1) antibody
  • malignant T-cell amplified sequence 1 S homeolog (mcts1.S) antibody
  • monocarboxylate transporter 1 (MCT1) antibody
  • 1500019M23Rik antibody
  • mct-1 antibody
  • MCT-1A antibody
  • mct1 antibody
  • MCTS1 antibody
  • MGC89874 antibody
  • zgc:56242 antibody

Protein level used designations for MCTS1

malignant T cell-amplified sequence 1 , malignant T-cell-amplified sequence 1 , multiple copies T-cell malignancies , multiple copies T-cell malignancies 1 , MCT-1 , malignant T cell amplified sequence 1 , Malignant T cell amplified sequence 1-A , malignant T cell-amplified sequence 1-A , malignant T-cell-amplified sequence 1-A

GENE ID SPECIES
28985 Homo sapiens
68995 Mus musculus
302500 Rattus norvegicus
394046 Danio rerio
422363 Gallus gallus
448679 Xenopus (Silurana) tropicalis
465836 Pan troglodytes
481038 Canis lupus familiaris
508412 Bos taurus
696543 Macaca mulatta
100528791 Ictalurus punctatus
503679 Xenopus laevis
780423 Sus scrofa
100714461 Cavia porcellus
100511797 Sus scrofa
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