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transports lactic acid and other monocarboxylic acids. Additionally we are shipping Malignant T Cell Amplified Sequence 1 Proteins (13) and Malignant T Cell Amplified Sequence 1 Kits (9) and many more products for this protein.
Showing 10 out of 85 products:
Human Polyclonal MCTS1 Primary Antibody for EIA, WB - ABIN453186
Kasiappan, Shih, Chu, Chen, Liu, Huang, Choy, Shu, Din, Chu, Hsu: Loss of p53 and MCT-1 overexpression synergistically promote chromosome instability and tumorigenicity. in Molecular cancer research : MCR 2009
Show all 3 references for 453186
Cow (Bovine) Polyclonal MCTS1 Primary Antibody for WB - ABIN2779047
Shi, Levenson, Gartenhaus: Identification and characterization of a novel enhancer for the human MCT-1 oncogene promoter. in Journal of cellular biochemistry 2003
Human Polyclonal MCTS1 Primary Antibody for WB - ABIN152954
Kumar, Kant, Singh et al.: Antitumor and chemosensitizing action of dichloroacetate implicates modulation of tumor microenvironment: a role of reorganized glucose metabolism, cell survival regulation and macrophage ... in Toxicology and applied pharmacology 2013
Human Polyclonal MCTS1 Primary Antibody for WB - ABIN4891880
Haas, Ngo, Li, Schleich, Qu, Vanyai, Cullen, Cardona-Alberich, Gladwyn-Ng, Pagnamenta, Taylor, Stewart, Kini, Duncan, Teleman, Keays, Heng: De Novo Mutations in DENR Disrupt Neuronal Development and Link Congenital Neurological Disorders to Faulty mRNA Translation Re-initiation. in Cell reports 2016
It was concluded that both MCT1 and CAII (show CA2 Antibodies) are involved in the homeostatic control of pH in skeletal muscle, both at rest and at the onset of exercise. The improved muscle function and resistance to fatigue in MCT1(+/-) mice remain unexplained.
MCT1 inhibition impairs proliferation of glycolytic breast cancer cells co-expressing MCT1 and MCT4 (show SLC16A3 Antibodies) via disruption of pyruvate rather than lactate export.
This study demonstrated that MCT1 was up regulation in ipsilateral site of brain afeter cerebral ischemia.
The soleus, liver and heart were the main tissues that showed improved the MCT1 mRNA expression, indicating its important role in controlling MLSS concentration in mice.
Exercise-induced changes in tumour LDH-B (show LDHB Antibodies) and MCT1 expression are modulated by oestrogen-related receptor alpha in breast cancer-bearing BALB/c mice
Chronic lactate administration after exercise increases MCT1 protein expression, which can be involved in the regulation of the observed increase in muscle glycogen (show GYS1 Antibodies) storage after exercise training.
This study showed that mouse MCT1, MCT2 (show SLC16A7 Antibodies), and MCT4 (show SLC16A3 Antibodies) are expressed in the PNS. While DRG neurons express MCT1, myelinating Schwann cells.
These data for the first time demonstrate that MCT1 is critical for regeneration of both sensory and motor axons in mice following sciatic nerve crush
Study demonstrated that PTEN (show PTEN Antibodies) loss and MCT-1 induction synergistically promoted the neoplastic multinucleation via the Src (show SRC Antibodies)/p190B (show ARHGAP5 Antibodies) signaling activation.
in Parkinson's disease, the levels of MCT1, MCT2 (show SLC16A7 Antibodies) and GLUT1 (show SLC2A1 Antibodies) is not changed following dopaminergic neurodegeneration
Reinitiation complexes involving initiation factors eIF2D (show EIF2D Antibodies), MCT-1 (show CMA1 Antibodies), and DENR (show DENR Antibodies) controls the translation of a large fraction of mammalian cellular mRNAs.
Increased miR (show MLXIP Antibodies)-210 and concomitant decreased ISCU (show ISCU Antibodies) RNA levels were found in ~40% of tumors and this was significantly associated with HIF-1alpha (show HIF1A Antibodies) and CAIX (show CA9 Antibodies), but not MCT1 (show CMA1 Antibodies) or MCT4 (show SLC16A4 Antibodies), over-expression.
Data show that metastasis-associated in colon cancer-1 (MACC1 (show MACC1 Antibodies)) and monocarboxylate transporter 1 (MCT1) are highly expressed in gastric cancer indicating poor prognosis.
AA genotype of the MCT1 (show CMA1 Antibodies) T1470A polymorphism is over-represented in wrestlers compared with controls and is associated with lower blood lactate concentrations after 30-s Wingate Anaerobic test and during intermittent sprint tests in Japanese wrestlers
MCT1 (show CMA1 Antibodies) and MCT4 (show SLC16A4 Antibodies) expression levels were associated with worse prognosis and shorter overall survival.
MCT1 (show CMA1 Antibodies) may be acting as an uptake transporter and MCT4 (show SLC16A4 Antibodies) as an efflux system across the basolateral membrane for ferulic acid, and that this process is stimulated by butyric acid.
After indirect co-culture, OP was increased in the BxPc-3 and Panc-1 cells; correspondingly, succinate dehydrogenase (show SDHA Antibodies), FH and MCT (show MCAT Antibodies) expression were increased. After the MCT1 (show CMA1 Antibodies)-specific inhibitor removed 'tumor-stromal' metabolic coupling, the migration and invasion abilities of the pancreatic cancer cells were decreased.
Data suggest that inhibition of mnocarboxylate transporters MCT1 (show CMA1 Antibodies) and MCT4 (show SLC16A4 Antibodies) may have clinical relevance in pancreatic ductal adenocarcinoma (PDAC).
Results found that MCT (show MCAT Antibodies) contributes to endothelial cell growth and tube formation via up-regulation of angiopoietin-1 (show ANGPT1 Antibodies) expression suggesting that MCT (show MCAT Antibodies) plays an important role in pancreatic cancer angiogenesis and tumor growth via activating the angiopoietin-1 (show ANGPT1 Antibodies) pathway.
The targeting of MCT1 (show CMA1 Antibodies) and PFKFB3 (show PFKFB3 Antibodies) regulated cell proliferation.
Data indicate that monocarboxylate transporters (MCTs1-4) were all found to be expressed in brains of embryos, and were localized in both neurons and astrocyte.
This study confirmed age-dependent changes of MCT1 expression in the rumen epithelium of newborn calves and showed that its expression might be affected by liquid feed type.
These findings show that MCT 1 increases with the development of rumen function and also in adult animals MCT 1 may change with the feeding.
The expression and distribution of monocarboxylate transporter 1 along the gastrointestinal tract of calves suggest it may play a role in transport of short chain fatty acids and their metabolites.
The results show that monocarboxylate transporter 1 (MCT1) is a major route for short chain fatty acids (SCFA) efflux across the basolateral membrane of bovine large intestine and that it could play a role in the regulation of intracellular pH.
Data suggest that expression of MCT1 in intestinal mucosa can be altered by diet; here, expression of MCT1 is down-regulated in colonic mucosa by high-protein diet and appears to be linked to fermentation of dietary proteins by intestinal microbes.
MCT1-mRNA showed a higher expression in the ileum; feeding inulin-coated butyrate resulted in an increased ileal surface; delivery of butyrate to the colon requires a more resistant inulin-coating.
The protein encoded by this gene is a proton-linked monocarboxylate transporter that catalyzes the movement of many monocarboxylates, such as lactate and pyruvate, across the plasma membrane. Mutations in this gene are associated with erythrocyte lactate transporter defect. Alternatively spliced transcript variants have been found for this gene.
malignant T cell amplified sequence 1
, malignant T cell-amplified sequence 1
, malignant T-cell-amplified sequence 1
, multiple copies T-cell malignancies
, multiple copies T-cell malignancies 1
, Malignant T cell amplified sequence 1-A
, malignant T cell-amplified sequence 1-A
, malignant T-cell-amplified sequence 1-A
, MCT 1
, monocarboxylate transporter 1
, solute carrier family 16 (monocarboxylic acid transporters), member 1
, solute carrier family 16 member 1
, solute carrier family 16, member 1 (monocarboxylic acid transporter 1)
, solute carrier 16 (monocarboxylic acid transporter), member 1
, monocarboxylate transporter 1a