Malignant T Cell Amplified Sequence 1 Proteins (MCTS1)

The protein encoded by MCTS1 is a proton-linked monocarboxylate transporter that catalyzes the movement of many monocarboxylates, such as lactate and pyruvate, across the plasma membrane. Additionally we are shipping Malignant T Cell Amplified Sequence 1 Antibodies (85) and Malignant T Cell Amplified Sequence 1 Kits (9) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
MCTS1 17236  
MCTS1 28985 Q9ULC4
MCTS1 302500 Q4G009
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Top Malignant T Cell Amplified Sequence 1 Proteins at antibodies-online.com

Showing 10 out of 13 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag 100 μg Log in to see 15 to 19 Days
$319.00
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 30 to 35 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 30 to 35 Days
$4,331.68
Details
HOST_HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Log in to see 20 Days
$785.40
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 11 to 12 Days
$405.71
Details
HOST_Escherichia coli (E. coli) Human His-SUMO Tag   50 μg Log in to see 11 Days
$341.00
Details
Yeast Cow His tag   1 mg Log in to see 60 to 71 Days
$2,427.33
Details
Yeast Zebrafish His tag   1 mg Log in to see 60 to 71 Days
$2,427.33
Details
Yeast Rat His tag   1 mg Log in to see 60 to 71 Days
$2,429.17
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   100 μg Log in to see 2 to 3 Days
$382.86
Details

MCTS1 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)

Human , ,
, , ,
Rat (Rattus)

Top referenced Malignant T Cell Amplified Sequence 1 Proteins

  1. Human MCTS1 Protein expressed in Escherichia coli (E. coli) - ABIN1098561 : Herbert, Shi, Gartenhaus: Expression and stabilization of the MCT-1 protein by DNA damaging agents. in Oncogene 2001 (PubMed)
    Show all 2 references for 1098561

More Proteins for Malignant T Cell Amplified Sequence 1 (MCTS1) Interaction Partners

Mouse (Murine) Malignant T Cell Amplified Sequence 1 (MCTS1) interaction partners

  1. It was concluded that both MCT1 and CAII (show CA2 Proteins) are involved in the homeostatic control of pH in skeletal muscle, both at rest and at the onset of exercise. The improved muscle function and resistance to fatigue in MCT1(+/-) mice remain unexplained.

  2. MCT1 inhibition impairs proliferation of glycolytic breast cancer cells co-expressing MCT1 and MCT4 (show SLC16A3 Proteins) via disruption of pyruvate rather than lactate export.

  3. This study demonstrated that MCT1 was up regulation in ipsilateral site of brain afeter cerebral ischemia.

  4. The soleus, liver and heart were the main tissues that showed improved the MCT1 mRNA expression, indicating its important role in controlling MLSS concentration in mice.

  5. Exercise-induced changes in tumour LDH-B (show LDHB Proteins) and MCT1 expression are modulated by oestrogen-related receptor alpha in breast cancer-bearing BALB/c mice

  6. Chronic lactate administration after exercise increases MCT1 protein expression, which can be involved in the regulation of the observed increase in muscle glycogen (show GYS1 Proteins) storage after exercise training.

  7. This study showed that mouse MCT1, MCT2, and MCT4 (show SLC16A3 Proteins) are expressed in the PNS. While DRG neurons express MCT1, myelinating Schwann cells.

  8. These data for the first time demonstrate that MCT1 is critical for regeneration of both sensory and motor axons in mice following sciatic nerve crush

  9. Study demonstrated that PTEN loss and MCT-1 induction synergistically promoted the neoplastic multinucleation via the Src/p190B signaling activation.

  10. in Parkinson's disease, the levels of MCT1, MCT2 and GLUT1 (show SLC2A1 Proteins) is not changed following dopaminergic neurodegeneration

Human Malignant T Cell Amplified Sequence 1 (MCTS1) interaction partners

  1. Reinitiation complexes involving initiation factors eIF2D (show EIF2D Proteins), MCT-1 (show CMA1 Proteins), and DENR (show DENR Proteins) controls the translation of a large fraction of mammalian cellular mRNAs.

  2. Increased miR (show MLXIP Proteins)-210 and concomitant decreased ISCU (show ISCU Proteins) RNA levels were found in ~40% of tumors and this was significantly associated with HIF-1alpha (show HIF1A Proteins) and CAIX (show CA9 Proteins), but not MCT1 (show CMA1 Proteins) or MCT4 (show SLC16A4 Proteins), over-expression.

  3. Data show that metastasis-associated in colon cancer-1 (MACC1 (show MACC1 Proteins)) and monocarboxylate transporter 1 (MCT1) are highly expressed in gastric cancer indicating poor prognosis.

  4. AA genotype of the MCT1 (show CMA1 Proteins) T1470A polymorphism is over-represented in wrestlers compared with controls and is associated with lower blood lactate concentrations after 30-s Wingate Anaerobic test and during intermittent sprint tests in Japanese wrestlers

  5. MCT1 (show CMA1 Proteins) and MCT4 (show SLC16A4 Proteins) expression levels were associated with worse prognosis and shorter overall survival.

  6. MCT1 (show CMA1 Proteins) may be acting as an uptake transporter and MCT4 (show SLC16A4 Proteins) as an efflux system across the basolateral membrane for ferulic acid, and that this process is stimulated by butyric acid.

  7. After indirect co-culture, OP was increased in the BxPc-3 and Panc-1 cells; correspondingly, succinate dehydrogenase (show SDHA Proteins), FH and MCT (show MCAT Proteins) expression were increased. After the MCT1 (show CMA1 Proteins)-specific inhibitor removed 'tumor-stromal' metabolic coupling, the migration and invasion abilities of the pancreatic cancer cells were decreased.

  8. Data suggest that inhibition of mnocarboxylate transporters MCT1 (show CMA1 Proteins) and MCT4 (show SLC16A4 Proteins) may have clinical relevance in pancreatic ductal adenocarcinoma (PDAC).

  9. Results found that MCT (show MCAT Proteins) contributes to endothelial cell growth and tube formation via up-regulation of angiopoietin-1 (show ANGPT1 Proteins) expression suggesting that MCT (show MCAT Proteins) plays an important role in pancreatic cancer angiogenesis and tumor growth via activating the angiopoietin-1 (show ANGPT1 Proteins) pathway.

  10. The targeting of MCT1 (show CMA1 Proteins) and PFKFB3 (show PFKFB3 Proteins) regulated cell proliferation.

Zebrafish Malignant T Cell Amplified Sequence 1 (MCTS1) interaction partners

  1. Data indicate that monocarboxylate transporters (MCTs1-4) were all found to be expressed in brains of embryos, and were localized in both neurons and astrocyte.

Cow (Bovine) Malignant T Cell Amplified Sequence 1 (MCTS1) interaction partners

  1. This study confirmed age-dependent changes of MCT1 expression in the rumen epithelium of newborn calves and showed that its expression might be affected by liquid feed type.

  2. These findings show that MCT 1 increases with the development of rumen function and also in adult animals MCT 1 may change with the feeding.

  3. The expression and distribution of monocarboxylate transporter 1 along the gastrointestinal tract of calves suggest it may play a role in transport of short chain fatty acids and their metabolites.

  4. The results show that monocarboxylate transporter 1 (MCT1) is a major route for short chain fatty acids (SCFA) efflux across the basolateral membrane of bovine large intestine and that it could play a role in the regulation of intracellular pH.

Pig (Porcine) Malignant T Cell Amplified Sequence 1 (MCTS1) interaction partners

  1. Data suggest that expression of MCT1 in intestinal mucosa can be altered by diet; here, expression of MCT1 is down-regulated in colonic mucosa by high-protein diet and appears to be linked to fermentation of dietary proteins by intestinal microbes.

  2. MCT1-mRNA showed a higher expression in the ileum; feeding inulin-coated butyrate resulted in an increased ileal surface; delivery of butyrate to the colon requires a more resistant inulin-coating.

Malignant T Cell Amplified Sequence 1 (MCTS1) Protein Profile

Protein Summary

The protein encoded by this gene is a proton-linked monocarboxylate transporter that catalyzes the movement of many monocarboxylates, such as lactate and pyruvate, across the plasma membrane. Mutations in this gene are associated with erythrocyte lactate transporter defect. Alternatively spliced transcript variants have been found for this gene.

Gene names and symbols associated with MCTS1

  • modifier of curly tail 1 (mct1)
  • malignant T cell amplified sequence 1 (TEgg094c21.2)
  • malignant T cell amplified sequence 1 (MCTS1)
  • malignant T cell amplified sequence 1 (mcts1)
  • malignant T cell amplified sequence 1 (Mcts1)
  • malignant T cell amplified sequence 1 (mcts1-a)
  • monocarboxylate transporter 1 (MCT1)
  • solute carrier family 16 (monocarboxylate transporter), member 1 (SLC16A1)
  • solute carrier family 16 (monocarboxylate transporter), member 1 (Slc16a1)
  • solute carrier family 16 (monocarboxylic acid transporters), member 1 (Slc16a1)
  • solute carrier family 16 (monocarboxylic acid transporters), member 1 (slc16a1)
  • solute carrier family 16, member 1 (monocarboxylic acid transporter 1) (SLC16A1)
  • 1500019M23Rik protein
  • AL022710 protein
  • cb517 protein
  • HHF7 protein
  • MCT protein
  • mct-1 protein
  • MCT-1A protein
  • Mct1 protein
  • MCT1a protein
  • MCTS1 protein
  • MGC89874 protein
  • RATMCT1 protein
  • RNMCT1 protein
  • zgc:55682 protein
  • zgc:56242 protein

Protein level used designations for MCTS1

malignant T cell amplified sequence 1 , malignant T cell-amplified sequence 1 , malignant T-cell-amplified sequence 1 , multiple copies T-cell malignancies , multiple copies T-cell malignancies 1 , MCT-1 , Malignant T cell amplified sequence 1-A , malignant T cell-amplified sequence 1-A , malignant T-cell-amplified sequence 1-A , MCT 1 , monocarboxylate transporter 1 , solute carrier family 16 (monocarboxylic acid transporters), member 1 , solute carrier family 16 member 1 , solute carrier family 16, member 1 (monocarboxylic acid transporter 1) , solute carrier 16 (monocarboxylic acid transporter), member 1 , MCT1 , monocarboxylate transporter 1a

GENE ID SPECIES
17236 Mus musculus
448679 Xenopus (Silurana) tropicalis
465836 Pan troglodytes
696543 Macaca mulatta
100528791 Ictalurus punctatus
28985 Homo sapiens
68995 Mus musculus
394046 Danio rerio
503679 Xenopus laevis
422363 Gallus gallus
481038 Canis lupus familiaris
508412 Bos taurus
302500 Rattus norvegicus
780423 Sus scrofa
6566 Homo sapiens
25027 Rattus norvegicus
20501 Mus musculus
368274 Danio rerio
475856 Canis lupus familiaris
505775 Bos taurus
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