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anti-Mannose Receptor, C Type 2 (MRC2) Antibodies

MRC2 encodes a member of the mannose receptor family of proteins that contain a fibronectin type II domain and multiple C-type lectin-like domains. Additionally we are shipping MRC2 Kits (16) and MRC2 Proteins (6) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
MRC2 498011 Q4TU93
MRC2 9902 Q9UBG0
MRC2 17534 Q64449
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Top anti-MRC2 Antibodies at antibodies-online.com

Showing 10 out of 49 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated WB Western blot analysis in NCI-H460 cell line lysates (35ug/lane) using CD280 / MRC2 Antibody . This demonstrates this antibody detected the MRC2 protein (arrow). 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated IF, IHC, ELISA, WB Western blot analysis of extracts from 293 cells, using MRC2 Antibody. The lane on the right is treated with the synthesized peptide. Immunohistochemistry analysis of paraffin-embedded human brain tissue, using MRC2 Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated WB MRC2 Antibody (Center)  western blot analysis in NCI-H460 cell line lysates (35ug/lane).This demonstrates the MRC2 antibody detected the MRC2 protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated IF (p), IHC (p), WB U937 cells probed with Rabbit Anti-MRC2 Polyclonal Antibody (ABIN872444) at 1:50 for 40 minutes followed by incubation with Goat Anti-Rabbit IgG PE conjugated secondary  at 1:100 (green) for 40 minutes compared to control cells (blue). 100 μL Log in to see 3 to 7 Days
$269.50
Details
Human Rabbit Un-conjugated IF, IHC (p), ELISA, WB 100 μL Log in to see 8 to 10 Days
$478.50
Details
Human Rabbit Un-conjugated IF, IHC, ELISA, WB 100 μg Log in to see 11 to 16 Days
$412.86
Details
Human Rabbit Un-conjugated ELISA, IF, IHC, WB 100 μL Log in to see 14 Days
$201.19
Details
Human Rabbit Un-conjugated ELISA, WB 100 μL Log in to see 14 Days
$201.19
Details
Human Rabbit FITC IF (p)   100 μL Log in to see 14 to 21 Days
$357.50
Details
Human Rabbit Biotin IHC (p), WB   100 μL Log in to see 14 to 21 Days
$357.50
Details

MRC2 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-MRC2 Antibodies

  1. Human Polyclonal MRC2 Primary Antibody for WB - ABIN951275 : Messaritou, East, Roghi, Isacke, Yarwood: Membrane type-1 matrix metalloproteinase activity is regulated by the endocytic collagen receptor Endo180. in Journal of cell science 2009 (PubMed)
    Show all 5 references for ABIN951275

More Antibodies against MRC2 Interaction Partners

Cow (Bovine) Mannose Receptor, C Type 2 (MRC2) interaction partners

  1. A second loss-of-function mutation in the bovine mannose receptor C (MRC2) gene causes illegitimate receptor oligomerization, which is predicted to impair function of the MRC2 encoded protein, Endo180.

  2. The positional identification of a 2-bp deletion in the open reading frame of the MRC2 receptor causing the recessive Crooked (show LRP6 Antibodies) Tail Syndrome in cattle, isdescribed.

Human Mannose Receptor, C Type 2 (MRC2) interaction partners

  1. A model of the ligand-binding region of uPARAP was obtained by molecular replacement.

  2. The positive correlation between suPLAUR expression and body mass index, suggests that leukocyte recruitment in obese tissue may be regulated, at least in part, through the splicing of the PLAUR (show PLAUR Antibodies) transcript.

  3. Our findings identify sarcoma cell-resident uPARAP/Endo180 as a central player in the bone degeneration of advanced osteosarcoma

  4. Study identifies the interaction between lectin domain in Endo180 and CD147 as an Epithelial-to-mesenchymal transition suppressor and indicates that stabilization of this molecular complex improves prostate cancer survival rates.

  5. AGE-dependent modification of the basal lamina induces invasive behaviour in non-transformed prostate epithelial cells via Endo180 pathway linked to cancer progression.

  6. MRC2 is downregulated by UVA irradiation and reduces collagen internalization; this can be recovered by all-trans retinoic acid

  7. Our findings correlate for the first time impaired collagen uptake via Endo180 with the pericellular accumulation of collagen fragments during photoaging.

  8. TGFbeta1 (show TGFB1 Antibodies)-Endo180-dependent collagen deposition is dysregulated at the tumour-stromal interface in bone metastasis.

  9. A novel functional role of collagen glycosylation: interaction with the endocytic collagen receptor (show ITGA2 Antibodies) uparap/ENDO180.

  10. Our present study suggests that uPARAP may be involved in glioma cell invasiveness through actin cytoskeletal rearrangement

Mouse (Murine) Mannose Receptor, C Type 2 (MRC2) interaction partners

  1. Our findings identify sarcoma cell-resident uPARAP/Endo180 as a central player in the bone degeneration of advanced osteosarcoma

  2. AGE-dependent modification of the basal lamina induces invasive behaviour in non-transformed prostate epithelial cells via Endo180 pathway linked to cancer progression.

  3. uPARAP function in cutaneous wound repair

  4. Both uPARAP and MMP-2 (show MMP2 Antibodies) take part in matrix turnover processes important for bone growth.

  5. Genetic ablation of the Mrc2 impaired the intracellular collagen degradation pathway.

  6. This function of uPARAP/Endo180 defines a novel role of intracellular collagen turnover in fibrosis protection.

  7. uPARAP is highly expressed in the murine lung, and loss of uPARAP leads to differences in lung mechanics, lung permeability, and collagen content after injury

  8. data establish an important fibrosis-attenuating role for Mrc2-expressing renal interstitial cells and suggest the involvement of a lysosomal collagen turnover pathway

  9. A novel functional role of collagen glycosylation: interaction with the endocytic collagen receptor (show ITGA2 Antibodies) uparap/ENDO180.

  10. targeted deletion of Endo180 exons 2-6 results in cells that have a defect in collagen binding and internalization and an impaired migratory phenotype

MRC2 Antigen Profile

Protein Summary

This gene encodes a member of the mannose receptor family of proteins that contain a fibronectin type II domain and multiple C-type lectin-like domains. The encoded protein plays a role in extracellular matrix remodeling by mediating the internalization and lysosomal degradation of collagen ligands. Expression of this gene may play a role in the tumorigenesis and metastasis of several malignancies including breast cancer, gliomas and metastatic bone disease.

Gene names and symbols associated with MRC2

  • mannose receptor, C type 2 (MRC2) antibody
  • mannose receptor, C type 2 (mrc2) antibody
  • mannose receptor, C type 2 (Mrc2) antibody
  • CD280 antibody
  • CLEC13E antibody
  • ENDO180 antibody
  • mKIAA0709 antibody
  • MRC2 antibody
  • uPARAP antibody

Protein level used designations for MRC2

mannose receptor, C type 2 , C-type mannose receptor 2 , C-type mannose receptor 2-like , collagen-binding factor Endo180 , endocytic receptor 180 , macrophage mannose receptor 2 , C-type lectin domain family 13 member E , UPAR-associated protein , endocytic receptor (macrophage mannose receptor family) , urokinase-type plasminogen activator receptor-associated protein , lectin lambda , novel lectin

GENE ID SPECIES
454788 Pan troglodytes
529049 Bos taurus
100004793 Danio rerio
100036697 Xenopus (Silurana) tropicalis
100406333 Callithrix jacchus
100541638 Meleagris gallopavo
498011 Rattus norvegicus
9902 Homo sapiens
17534 Mus musculus
100688560 Canis lupus familiaris
100516106 Sus scrofa
419950 Gallus gallus
Selected quality suppliers for anti-MRC2 (MRC2) Antibodies
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