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anti-Mannosidase, Alpha, Class 1B, Member 1 (MAN1B1) Antibodies

MAN1B1 encodes an enzyme belonging to the glycosyl hydrolase 47 family. Additionally we are shipping MAN1B1 Proteins (8) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
MAN1B1 11253 Q9UKM7
MAN1B1 227619 A2AJ15
Anti-Rat MAN1B1 MAN1B1 499751 B2GUY0
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Top anti-MAN1B1 Antibodies at antibodies-online.com

Showing 10 out of 21 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated IHC (p), WB IHC-P Image Immunohistochemical analysis of paraffin-embedded SCC25 xenograft, using MAN1B1, antibody at 1:100 dilution. IHC-P Image MAN1B1 antibody [C1C3] detects MAN1B1 protein at cytoplasm on mouse kidney by immunohistochemical analysis. Sample: Paraffin-embedded mouse kidney. MAN1B1 antibody [C1C3] , diluted at 1:500. 100 μL Log in to see 2 to 3 Days
$358.60
Details
Human Mouse Un-conjugated WB MAN1B1 monoclonal antibody (M01), clone 6B1 Western Blot analysis of MAN1B1 expression in A-431. 0.1 mg Log in to see 8 to 11 Days
$450.00
Details
Human Rabbit Un-conjugated ELISA, WB 100 μL Log in to see 14 Days
$201.19
Details
Human Mouse Un-conjugated IHC (p), ELISA, WB Immunoperoxidase of monoclonal antibody to MAN1B1 on formalin-fixed paraffin-embedded human stomach. [antibody concentration 3 ug/ml] MAN1B1 monoclonal antibody (M01), clone 6B1 Western Blot analysis of MAN1B1 expression in A-431 . 100 μg Log in to see 9 Days
$430.00
Details
Human Rabbit Un-conjugated IHC (fp), WB 100 μL Log in to see 6 to 11 Days
$485.71
Details
Human Rabbit Un-conjugated IHC (p), WB   100 μL Log in to see 8 to 10 Days
$507.83
Details
Human Mouse APC IHC, ELISA, WB   100 μL Log in to see 8 to 10 Days
$925.83
Details
Human Mouse FITC IHC, ELISA, WB   100 μL Log in to see 8 to 10 Days
$925.83
Details
Human Mouse PE IHC, ELISA, WB   100 μL Log in to see 8 to 10 Days
$925.83
Details
Human Mouse Alkaline Phosphatase (AP) IHC, ELISA, WB   100 μL Log in to see 8 to 10 Days
$925.83
Details

MAN1B1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Human ,
,
,
, , ,
Mouse (Murine)


More Antibodies against MAN1B1 Interaction Partners

Human Mannosidase, Alpha, Class 1B, Member 1 (MAN1B1) interaction partners

  1. Data show that HIV-1 env (show ERVW-1 Antibodies) protein interacts with alpha-mannosidases ERManI (MAN1B1) and initiates endoplasmic reticulum (ER)-associated protein degradation (ERAD) pathway degradation process.

  2. The properties of ERMAN1 enable rapid selection of endoplasmic reticulum-associated degradation substrates in the endoplasmic reticulum.ERMAN1 digests mono-, di- and tri (show VANGL2 Antibodies)-glucosylated N-glycans.

  3. we linked mutations in MAN1B1 to a Golgi glycosylation disorder. Additionally, our results support the recent findings on MAN1B1 localization

  4. MAN1B1 deficiency appeared to be a frequent cause in our cohort of patients with unsolved congenital disorder of glycosylation type II.

  5. A novel post-transcriptional regulatory mechanism for ERManI via miR (show MLXIP Antibodies)-125b and this molecule contributes to the regulation of carcinogenesis in hepatocellular carcinoma.

  6. ERManI and gamma-COP (show COPg1 Antibodies) contribute to a golgi-based quality control module that facilitates the retrieval of captured ERAD substrates back to the endoplasmic reticulum.

  7. A homozygous nonsense mutation in MAN1B1 segregated with nonsyndromic autosomal-recessive intellectual disability and additional dysmorphic features.

  8. ER processing alpha1,2-mannosidase (ER ManI) has a role in ER-associated degradation of misfolded proteins

  9. Modification by endoplasmic reticulum mannosidase I (ERManI) contributes to the preferential selection of the misfolded AAT (show SERPINA1A Antibodies) monomer for proteasomal degradation.

  10. overexpression of Golgi alpha1,2-mannosidase IA, IB, and IC also accelerates ERAD of terminally misfolded human alpha1-antitrypsin variant null (Hong Kong) (NHK), and mannose trimming from the N-glycans on NHK in 293 cells

MAN1B1 Antigen Profile

Protein Summary

This gene encodes an enzyme belonging to the glycosyl hydrolase 47 family. This enzyme functions in N-glycan biosynthesis, and is a class I alpha-1,2-mannosidase that specifically converts Man9GlcNAc to Man8GlcNAc isomer B. It is required for N-glycan trimming to Man5-6GlcNAc2 in the endoplasmic-reticulum-associated degradation pathway. Mutations in this gene cause autosomal-recessive intellectual disability. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 11.

Gene names and symbols associated with MAN1B1

  • mannosidase, alpha, class 1B, member 1 (MAN1B1) antibody
  • mannosidase, alpha, class 1B, member 1 (man1b1) antibody
  • mannosidase, alpha, class 1B, member 1 (Man1b1) antibody
  • E430019H13Rik antibody
  • ERMan1 antibody
  • Gm108 antibody
  • MAN1B1 antibody
  • MANA-ER antibody
  • MRT15 antibody
  • RGD1563595 antibody

Protein level used designations for MAN1B1

mannosidase, alpha, class 1B, member 1 , alpha 1,2-mannosidase , ER alpha 1,2-mannosidase , Man9GlcNAc2-specific processing alpha-mannosidase , endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase , endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase 1 , ER alpha-1,2-mannosidase , ER mannosidase 1 , man9GlcNAc2-specific-processing alpha-mannosidase

GENE ID SPECIES
417296 Gallus gallus
447291 Xenopus laevis
473099 Pan troglodytes
480667 Canis lupus familiaris
100145194 Xenopus (Silurana) tropicalis
11253 Homo sapiens
227619 Mus musculus
499751 Rattus norvegicus
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