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Mannosyl (Alpha-1,6-)-Glycoprotein beta-1,2-N-Acetylglucosaminyltransferase Proteins (MGAT2)

The product of MGAT2 is a Golgi enzyme catalyzing an essential step in the conversion of oligomannose to complex N-glycans. Additionally we are shipping MGAT2 Antibodies (50) and MGAT2 Kits (21) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
MGAT2 217664 Q921V5
MGAT2 4247 Q10469
Rat MGAT2 MGAT2 94273 Q09326
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Top MGAT2 Proteins at

Showing 8 out of 8 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific pu... 1 mg Log in to see 29 to 34 Days
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific pu... 0.5 mg Log in to see 49 to 54 Days
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific pu... 0.25 mg Log in to see 49 to 54 Days
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific pu... 1 mg Log in to see 29 to 34 Days
HOST_Wheat germ Human GST tag 2 μg Log in to see 9 Days
HOST_HEK293 Human His tag   500 μg Log in to see 5 Days
HOST_Escherichia coli (E. coli) Human Un-conjugated   100 μg Log in to see 3 to 4 Days
HOST_Human Human Un-conjugated   10 μg Log in to see 11 to 14 Days

MGAT2 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine) ,
Human , , , ,
, ,

More Proteins for Mannosyl (Alpha-1,6-)-Glycoprotein beta-1,2-N-Acetylglucosaminyltransferase (MGAT2) Interaction Partners

Mouse (Murine) Mannosyl (Alpha-1,6-)-Glycoprotein beta-1,2-N-Acetylglucosaminyltransferase (MGAT2) interaction partners

  1. beneficial effects of vertical sleeve gastrectomy on body weight and glucose metabolism are independent of MGAT2 activity

  2. MGAT2 in the intestine plays an indispensable role in enhancing metabolic efficiency but also raise the possibility that MGAT2 in other tissues may contribute to the regulation of energy metabolism.

  3. The results suggest that MGAT2 has a pivotal role in lipid metabolism in the small intestine, and the inhibition of MGAT2 activity may be a promising strategy for the treatment of obesity-related metabolic disorders.

  4. MGAT2 may play an important role in dietary fat absorption

  5. MGAT catalyzes the synthesis of diacylglycerol, a precursor of triacylglycerol. MGAT mediates the absorption of dietary fat by catalyzing the resynthesis of triacylglycerol in enterocytes, a step required for delivering absorbed fat to other tissues.

  6. investigated the expression of murine MGAT2 protein along the intestinal tract, determined its subcellular localization, and studied its regulation by diet and in db/db (show LEPR Proteins) mouse

  7. analysis of developmental and nutritional regulation of monoacylglyceanalysis of developmental and nutritional regulation of monoacylglycerol lipase (show MGLL Proteins) and monoacylglycerol acyltransferaserol lipase (show LIPG Proteins) and monoacylglycerol acyltransferase

  8. MGAT2 possessed an intrinsic acyl-CoA:diacylglycerol acyltransferase (DGAT) activity which could provide an alternative pathway for triacylglycerol synthesis in the absence of DGAT

  9. Mogat2 (show MOGAT2 Proteins) is a key determinant of energy metabolism in response to dietary fat and suggest that inhibition or deletion of this enzyme may prove to be a useful strategy for treating obesity.

  10. the release of gut (show GUSB Proteins) peptides following oral triglyceride ingestion in MGAT2 and DGAT1 (show DGAT1 Proteins) knock-out mice was investigated.

Human Mannosyl (Alpha-1,6-)-Glycoprotein beta-1,2-N-Acetylglucosaminyltransferase (MGAT2) interaction partners

  1. UDP-galactose (show B4GALT1 Proteins) (SLC35A2 (show SLC35A2 Proteins)) and UDP-N-acetylglucosamine (show MGAT4B Proteins) (SLC35A3 (show SLC35A3 Proteins)) Transporters Form Glycosylation-related Complexes with Mannoside Acetylglucosaminyltransferases (Mgats).

  2. The described cell-based assay adds a new methodology for the development and evaluation of MGAT2 inhibitors for the treatment of obesity and type 2 diabetes

  3. Mogat2 (show MOGAT2 Proteins)(IKO) mice increased energy expenditure although to a lesser degree than Mogat2 (show MOGAT2 Proteins)(-/-) mice and were protected against diet-induced weight gain and associated comorbidities

  4. MGAT2 functions as a dimeric or tetrameric protein and selectively heterodimerizes with DGAT1 (show DGAT1 Proteins) in mammalian cells

  5. Golgi N-glycosyltransferases beta-1,2-N-acetylglucosaminyltransferase I (show MGAT1 Proteins), beta-1,2-N-acetylglucosaminyltransferase II, 1,4-galactosyltransferase I (show B4GALT7 Proteins), and alpha-2,6-sialyltransferase (show ST6GAL2 Proteins) I form both homo- and heterodimeric enzyme complexes in live cells

  6. MGAT2 is a monoacylglycerol acyltransferase expressed in the small intestine

MGAT2 Protein Profile

Protein Summary

The product of this gene is a Golgi enzyme catalyzing an essential step in the conversion of oligomannose to complex N-glycans. The enzyme has the typical glycosyltransferase domains: a short N-terminal cytoplasmic domain, a hydrophobic non-cleavable signal-anchor domain, and a C-terminal catalytic domain. Mutations in this gene may lead to carbohydrate-deficient glycoprotein syndrome, type II. The coding region of this gene is intronless. Transcript variants with a spliced 5' UTR may exist, but their biological validity has not been determined.

Gene names and symbols associated with MGAT2

  • CG7921 gene product from transcript CG7921-RB (Mgat2)
  • mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase (MGAT2)
  • mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase (mgat2)
  • alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase-like (MGAT2)
  • mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase (LOC790576)
  • mannoside acetylglucosaminyltransferase 2 (Mgat2)
  • mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase (Mgat2)
  • monoacylglycerol O-acyltransferase 2 (mogat2)
  • monoacylglycerol O-acyltransferase 2 (Mogat2)
  • AA407964 protein
  • CDG2A protein
  • CDGS2 protein
  • CG7921 protein
  • DGAT2L5 protein
  • Dmel\\CG7921 protein
  • dMGAT2 protein
  • GlcNAc-TII protein
  • GlcNAcT2 protein
  • GLCNACTII protein
  • GNT-II protein
  • Gnt2 protein
  • Mgat1l protein
  • MGAT2 protein
  • MGC89475 protein
  • wu:fb94h05 protein
  • zgc:101667 protein

Protein level used designations for MGAT2

CG7921-PA , CG7921-PB , CG7921-PC , Mgat2-PA , Mgat2-PB , Mgat2-PC , mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase , alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase , alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase-like , N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase II , beta-1,2-N-acetylglucosaminyltransferase II , glcNAc-T II , Beta-1,2-N-acetylglucosaminyltransferase II , UDP-N-acetylglucosamine:alpha-6-D-mannoside beta-1,2-N-acetylglucosaminyltransferase II , mannoside acetylglucosaminyltransferase 2 , GNT-II , beta-12-N-acetylglucosaminyltransferase II , 2-acylglycerol O-acyltransferase 2 , MGAT2 , acyl CoA:monoacylglycerol acyltransferase 2 , acyl-CoA:monoacylglycerol acyltransferase 2 , diacylglycerol acyltransferase 2-like protein 5

43563 Drosophila melanogaster
480312 Canis lupus familiaris
448439 Xenopus (Silurana) tropicalis
706426 Macaca mulatta
740608 Pan troglodytes
100023862 Monodelphis domestica
100348676 Oryctolagus cuniculus
100403225 Callithrix jacchus
100460559 Pongo abelii
100469937 Ailuropoda melanoleuca
790576 Bos taurus
217664 Mus musculus
4247 Homo sapiens
94273 Rattus norvegicus
414590 Xenopus laevis
100151745 Sus scrofa
539918 Bos taurus
101122525 Ovis aries
450063 Danio rerio
233549 Mus musculus
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