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anti-Mastermind-Like 2 (Drosophila) (MAML2) Antibodies

Acts as a transcriptional coactivator for NOTCH proteins. Additionally we are shipping and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
MAML2 270118  
MAML2 689844  
MAML2 84441 Q8IZL2
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Top anti-MAML2 Antibodies at antibodies-online.com

Showing 10 out of 41 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated WB Host: Rabbit  Target Name: Maml2  Sample Tissue: Mouse Stomach lysates  Antibody Dilution: 1.0 µg/mL 100 μL Log in to see 2 to 3 Days
$289.00
Details
Mouse Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Mouse Un-conjugated WB MAML2 monoclonal antibody (M03), clone 4A1 Western Blot analysis of MAML2 expression in MCF-7. Detection limit for recombinant GST tagged MAML2 is approximately 1 ng/mL as a capture antibody. 0.1 mg Log in to see 8 to 11 Days
$450.00
Details
Mouse Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Mouse Un-conjugated ELISA, WB MAML2 monoclonal antibody (M03), clone 4A1 Western Blot analysis of MAML2 expression in MCF-7 . Detection limit for recombinant GST tagged MAML2 is approximately 1ng/ml as a capture antibody. 100 μg Log in to see 9 Days
$430.00
Details
Human Mouse Un-conjugated ELISA, WB Western Blot detection against Immunogen (37 KDa) . 50 μL Log in to see 9 Days
$298.57
Details
Human Mouse FITC ELISA, WB   100 μL Log in to see 8 to 10 Days
$925.83
Details
Human Mouse PE ELISA, WB   100 μL Log in to see 8 to 10 Days
$925.83
Details
Human Mouse Alkaline Phosphatase (AP) ELISA, WB   100 μL Log in to see 8 to 10 Days
$925.83
Details
Human Mouse Biotin ELISA, WB   100 μL Log in to see 8 to 10 Days
$925.83
Details

MAML2 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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More Antibodies against MAML2 Interaction Partners

Human Mastermind-Like 2 (Drosophila) (MAML2) interaction partners

  1. Detection of the CRTC1 (show CRTC1 Antibodies)/MAML2 fusion transcript provides useful information for MEC (show CCL28 Antibodies) diagnosis but is not associated with differences in survival outcomes.

  2. The molecular basis underlying CRTC1 (show CRTC1 Antibodies)-MAML2 oncogenic functions were identified in mucoepidermoid carcinoma cells.

  3. SNPs in Notch (show NOTCH1 Antibodies) pathway genes may be predictors of cutaneous melanoma disease-specific survival.

  4. We identified MAML2 rearrangements in five of nine odontogenic cysts lined by mucus-secreting cells

  5. Translocation t(11;19)(q14-21;p12-13) in patients with Salivary mucoepidermoid carcinoma was reported , which results in fusion between exons 1 and 2 of MAML2 on chromosome 11q21.Fusion positive, MAML2 re-arrangements are present in 50-70 % of MECs.

  6. The high sensitivity and specificity of MAML2 rearrangement for central mucoepidermoid carcinoma points to its utility as a diagnostic adjunct in separating mucinous cystic lesions of the gnathic bones.

  7. MAML2 rearrangement appears frequent in PMEC and specific with this tumor. Both the presence of MAML2 rearrangement and absence of FLT1 (show FLT1 Antibodies) tend to confer a favorable clinical outcome.

  8. Malignant mucoepidermoid salivary gland tumors can arise from a recurrent t (11, 19)(q21;p13.1) translocation that generates an unusual chimeric CRTC1 (show CRTC1 Antibodies)/MAML2 oncoprotein.

  9. The rearrangement between MAML2 and CXCR4 (show CXCR4 Antibodies), created by a t(2;11)(q22.1;q21) translocation, results in a new fusion gene in which a portion of CXCR4 (show CXCR4 Antibodies) is linked to the MAML2 gene.

  10. aberrantly activated AREG (show AREG Antibodies)-EGFR (show EGFR Antibodies) signaling is required for CRTC1 (show CRTC1 Antibodies)-MAML2-positive MEC (show CCL28 Antibodies) cell growth and survival, suggesting that EGFR (show EGFR Antibodies)-targeted therapies will benefit patients with advanced, unresectable CRTC1 (show CRTC1 Antibodies)-MAML2-positive MEC (show CCL28 Antibodies).

MAML2 Antigen Profile

Protein Summary

Acts as a transcriptional coactivator for NOTCH proteins. Has been shown to amplify NOTCH-induced transcription of HES1. Potentiates activation by NOTCH3 and NOTCH4 more efficiently than MAML1 or MAML3 (By similarity).

Gene names and symbols associated with MAML2

  • mastermind like 2 (Drosophila) (Maml2) antibody
  • mastermind-like 2 (Drosophila) (MAML2) antibody
  • 5930431H10 antibody
  • BC032967 antibody
  • MAM-3 antibody
  • MAM2 antibody
  • MAM3 antibody
  • MLL-MAML2 antibody

Protein level used designations for MAML2

mastermind like 2 , mastermind-like 2 , mastermind-like protein 2 , mam-2

GENE ID SPECIES
270118 Mus musculus
689844 Rattus norvegicus
84441 Homo sapiens
521194 Bos taurus
485116 Canis lupus familiaris
Selected quality suppliers for anti-MAML2 (MAML2) Antibodies
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