Maternal Embryonic Leucine Zipper Kinase (MELK) ELISA Kits

Serine/threonine-protein kinase involved in various processes such as cell cycle regulation, self-renewal of stem cells, apoptosis and splicing regulation (By similarity). Additionally we are shipping MELK Antibodies (142) and MELK Proteins (10) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
MELK 9833 Q14680
MELK 17279 Q61846
MELK 362510  
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Top MELK ELISA Kits at antibodies-online.com

Showing 4 out of 20 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Human 0.039 ng/mL 0.156-10 ng/mL Typical standard curve 96 Tests Log in to see 15 to 18 Days
$910.56
Details
Mouse 0.057 ng/mL 0.156-10 ng/mL 96 Tests Log in to see 15 to 17 Days
$929.89
Details
Rat 0.063 ng/mL 0.156-10 ng/mL 96 Tests Log in to see 15 to 17 Days
$973.11
Details
Human 0.098 ng/mL 0.156-10 ng/mL   96 Tests Log in to see 2 to 3 Days
$867.90
Details

More ELISA Kits for MELK Interaction Partners

Human Maternal Embryonic Leucine Zipper Kinase (MELK) interaction partners

  1. MELK-inhibitor has a role in triple-negative breast cancer cells demonstrating context-dependent response with p53 (show TP53 ELISA Kits) as a key determinant

  2. MELK is an oncogenic kinase involved in the pathogenesis and recurrence of hepatocellular carcinoma.

  3. Inhibition or depletion of MELK reduced cell proliferation and anchorage-dependent and -independent growth in various ovarian cancer cell lines through a G2/M cell cycle arrest, eventually resulting in apoptosis.

  4. Report IL11RA (show IL11RA ELISA Kits) and MELK amplification in gastric cancer cell lines and primary gastric adenocarcinomas.

  5. MELK expression in hepatocellular carcinoma is extremely intense compared to its expression reported in other types of cancer and could be a promising effective tumor marker of HCC (show FAM126A ELISA Kits).

  6. targeting MELK by the inhibition of both its catalytic activity and its protein stability might sensitize tumours to DNA-damaging agents or radiation therapy by lowering the DNA-damage threshold

  7. Together, these data indicate that MELK is a normally non-essential kinase, but is critical for basal-like breast cancer.

  8. EZH2 (show EZH2 ELISA Kits) protects glioma stem cells from radiation-induced cell death in a MELK/FOXM1 (show FOXM1 ELISA Kits)-dependent manner

  9. we report characterization of possible roles of MELK in acute myeloid leukemia (show BCL11A ELISA Kits)

  10. insight has been brought by the discovery of a protein complex of FOXM1 (show FOXM1 ELISA Kits) with the mitotic kinase MELK in cancer stem cells in brain cancers, as this protein complex appears to be cancer-specific

Mouse (Murine) Maternal Embryonic Leucine Zipper Kinase (MELK) interaction partners

  1. MELK promotes cell migration and invasion via the FAK (show PTK2 ELISA Kits)/Paxillin (show PXN ELISA Kits) pathway, and plays an important role in the occurrence and development of gastric cancer.

  2. Phosphorylation of the activation loop of MPK38 induces its movement resulting in kinase activation.

  3. These results indicate that Trx (show TXN ELISA Kits) functions as a physiological inhibitor of MPK38, which plays an important role in inducing ASK1 (show MAP3K5 ELISA Kits)-, TGF-beta (show TGFB1 ELISA Kits), and p53 (show TP53 ELISA Kits)-mediated activity

  4. an important role for MPK38-mediated phosphorylation of PDK1 (show PDPK1 ELISA Kits) in the negative regulation of PDK1 (show PDPK1 ELISA Kits) activity.

  5. MPK38 may act as a novel regulator for promoting p53 (show TP53 ELISA Kits) activity through direct phosphorylation of p53 (show TP53 ELISA Kits) at Ser (show SIGLEC1 ELISA Kits)(15).

  6. Upregulation of maternal embryonic leucine zipper kinase is associated with mammary tumor.

  7. MELK is necessary for proliferation of embryonic and postnatal MNP and suggest that it regulates the transition from GFAP (show GFAP ELISA Kits)-expressing progenitors to rapid amplifying progenitors in the postnatal brain.

  8. The characterization of two novel E2F (show E2F1 ELISA Kits) target genes, chromosome condensation-related SMC-associated protein 1 (Cnap1) and maternal embryonic leucine zipper kinase (Melk) is reported.

  9. MPK38 physically interacts with ASK1 (show MAP3K5 ELISA Kits) in vivo and acts as a positive upstream regulator of ASK1 (show MAP3K5 ELISA Kits)

Zebrafish Maternal Embryonic Leucine Zipper Kinase (MELK) interaction partners

  1. Melk-like gene may play a role in primitive hematopoiesis by affecting the expression of genes critical for hematopoiesis.

Xenopus laevis Maternal Embryonic Leucine Zipper Kinase (MELK) interaction partners

  1. Overexpression of xMELK leads to failure of cytokinesis and impairs accumulation RhoA- a pivotal regulator of cytokinesis.

  2. These results demonstrate the presence of a mitochondrial targeting signal at the N-terminus of the MC domain of MELK. This mitochondrial targeting signal was also functional in human HeLa cells.[MELK]

MELK Antigen Profile

Antigen Summary

Serine/threonine-protein kinase involved in various processes such as cell cycle regulation, self-renewal of stem cells, apoptosis and splicing regulation (By similarity). Also plays a role in primitive hematopoiesis, possibly by affecting the expression of genes critical for hematopoiesis.

Gene names and symbols associated with MELK

  • maternal embryonic leucine zipper kinase (MELK) antibody
  • maternal embryonic leucine zipper kinase (melk) antibody
  • maternal embryonic leucine zipper kinase (cgd5_2270) antibody
  • maternal embryonic leucine zipper kinase (Melk) antibody
  • AI327312 antibody
  • fb71b01 antibody
  • fe01f04 antibody
  • HPK38 antibody
  • Melk antibody
  • mKIAA0175 antibody
  • MPK38 antibody
  • wu:fb71b01 antibody
  • wu:fe01f04 antibody
  • xmelk antibody

Protein level used designations for MELK

maternal embryonic leucine zipper kinase , maternal embryonic leucine zipper kinase-like , pEg3 kinase , protein kinase Eg3 , protein kinase PK38 , tyrosine-protein kinase MELK , zMelk , Protein kinase Eg3

GENE ID SPECIES
428391 Gallus gallus
465095 Pan troglodytes
549144 Xenopus (Silurana) tropicalis
3373320 Cryptosporidium parvum Iowa II
100123808 Nasonia vitripennis
100386947 Callithrix jacchus
100586707 Nomascus leucogenys
9833 Homo sapiens
481608 Canis lupus familiaris
520088 Bos taurus
17279 Mus musculus
362510 Rattus norvegicus
30724 Danio rerio
397927 Xenopus laevis
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