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Matrilin 3 Proteins (MATN3)

MATN3 encodes a member of von Willebrand factor A domain containing protein family. Additionally we are shipping Matrilin 3 Antibodies (54) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
MATN3 4148 O15232
MATN3 17182 O35701
Rat MATN3 MATN3 313954  
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Top Matrilin 3 Proteins at antibodies-online.com

Showing 4 out of 4 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Yeast Chicken His tag   1 mg Log in to see 56 to 66 Days
$3,193.67
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

MATN3 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,

Mouse (Murine)

More Proteins for Matrilin 3 (MATN3) Interaction Partners

Human Matrilin 3 (MATN3) interaction partners

  1. This report is the first to show the involvement of MATN3 in C-type natriuretic peptide (show NPPC Proteins)/natriuretic peptide receptor-B signaling pathway during the process of transforming growth factor-beta induced (show TGFBI Proteins) chondrogenic differentiation of mesenchymal stem cells.

  2. MATN3 plays a regulatory role in cartilage homeostasis due to its capacity to induce IL-1Ra (show IL1RN Proteins), upregulate gene expression of major cartilage matrix components, and downregulate the expression of OA-associated matrix-degrading proteinases in chondrocytes.

  3. MATN3 may have the inherent ability to inhibit premature chondrocyte hypertrophy by suppressing BMP-2 (show BMP2 Proteins)/Smad1 (show GARS Proteins) activity

  4. The VWA1 (show VWA1 Proteins) domain of matrilin-3 is primarily responsible for the induction of IL-6 (show IL6 Proteins) release from primary human chondrocytes.

  5. Polymorphism in the MATN3 gene might play a role in osteoarthritis in the Chinese Han population.

  6. Haplotype-4 of MATN3 is associated with vertebral fracture risk independent of bone mineral density in Chinese postmenopausal women.

  7. MATN3 mutations were identified in 13 multiple epiphyseal dysplasia patients and comprised predominantly of missense mutations.

  8. Radiographic findings in patients with COMP (show COMP Proteins) and MATN3 mutations showed marked abnormalities in hip and knee joints.

  9. a matrilin-3 mutation associated with osteoarthritis does not affect collagen affinity but promotes the formation of wider cartilage collag (show COL2A1 Proteins)en fibrils

  10. increased expression of MATN3 in osteoarthritis might contribute to the degeneration of articular cartilage.

Mouse (Murine) Matrilin 3 (MATN3) interaction partners

  1. Data show that hand osteoarthritis (HOA)-related matrilin-3 mutation (T298M) leads to a high expression level of growth arrest DNA damage-inducible gene 153 (GADD153 (show DDIT3 Proteins))

  2. MATN3 plays a regulatory role in cartilage homeostasis due to its capacity to induce IL-1Ra (show IL1RN Proteins), upregulate gene expression of major cartilage matrix components, and downregulate the expression of OA-associated matrix-degrading proteinases in chondrocytes.

  3. MATN3 may have the inherent ability to inhibit premature chondrocyte hypertrophy by suppressing BMP-2 (show BMP2 Proteins)/Smad1 (show SMAD1 Proteins) activity

  4. study will facilitate better awareness of the differential diagnoses that might be associated with the PSACH (show COMP Proteins)/MED spectrum and subsequent care of PSACH (show COMP Proteins)/MED patients

  5. Lack of COMP (show COMP Proteins) and matrilin 3 leads to increased deposition of TIMP-3 (show TIMP3 Proteins), which causes partial inactivation of matrix metalloproteinases in bone, including MMP-13 (show MMP13 Proteins).

  6. Secretion of matrilin 3 V194D mutant protein is not dependent on hetero-oligomerization with matrilin 1 (show MATN1 Proteins).

  7. matrilin-3 mutation associated with osteoarthritis does not affect collagen affinity but promotes the formation of wider cartilage collagen (show COL2A1 Proteins) fibrils

  8. potential of matrilin-3 to modulate gene expression profile of primary chondrocytes; tested matrilin3-dependent induction of pro-inflammatory cytokines, inducible nitric oxide synthetase & cyclooxygenase-2 (show PTGS2 Proteins), MMP1 (show MMP1 Proteins), -3 & -13, & matrilin-3 itself

  9. Expression of matrilin-3 during maturation of mouse skeletal tissues

  10. To assess the function of matrilin-3 during skeletal development, we have generated Matn-3 null mice; phenotypes of multiple epiphyseal dysplasia disorders are not caused by the absence of matrilin-3 in cartilage ECM (show MMRN1 Proteins).

Cow (Bovine) Matrilin 3 (MATN3) interaction partners

Matrilin 3 (MATN3) Protein Profile

Protein Summary

This gene encodes a member of von Willebrand factor A domain containing protein family. This family of proteins is thought to be involved in the formation of filamentous networks in the extracellular matrices of various tissues. This protein contains two von Willebrand factor A domains\; it is present in the cartilage extracellular matrix and has a role in the development and homeostasis of cartilage and bone. Mutations in this gene result in multiple epiphyseal dysplasia.

Gene names and symbols associated with Matrilin 3 Proteins (MATN3)

  • matrilin 3 (MATN3)
  • matrilin 3 (LOC100221699)
  • matrilin 3 (Matn3)
  • AV009181 protein
  • DIPOA protein
  • EDM5 protein
  • HOA protein
  • OADIP protein
  • OS2 protein

Protein level used designations for Matrilin 3 Proteins (MATN3)

matrilin 3 , matrilin-3-like , matrilin-3

GENE ID SPECIES
459514 Pan troglodytes
482985 Canis lupus familiaris
716677 Macaca mulatta
100071902 Equus caballus
100221699 Taeniopygia guttata
100392004 Callithrix jacchus
100470832 Ailuropoda melanoleuca
100603025 Nomascus leucogenys
4148 Homo sapiens
17182 Mus musculus
313954 Rattus norvegicus
395954 Gallus gallus
540041 Bos taurus
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