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anti-Matrix Extracellular phosphoglycoprotein (MEPE) Antibodies

may play a role in bone homeostasis. Additionally we are shipping MEPE Kits (38) and and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
MEPE 56955 Q9NQ76
MEPE 79110  
MEPE 94111  
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Top anti-MEPE Antibodies at antibodies-online.com

Showing 10 out of 49 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated EIA, WB MEPE Antibody (N-term) western blot analysis in NCI-H460 cell line lysates (35µg/lane).This demonstrates the MEPE antibody detected the MEPE protein (arrow). 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated WB WB Suggested Anti-MEPE Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:62500Positive Control: Hela cell lysate WB Suggested Anti-MEPE  Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:.2500  Positive Control: Hela cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated WB MEPE Antibody (N-term) (ABIN656329) western blot analysis in NCI-H460 cell line lysates (35 µg/lane). This demonstrates the MEPE antibody detected the MEPE protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Rabbit Un-conjugated ICC, IHC (fro), IHC (p), ELISA, WB 100 μg Log in to see 9 to 11 Days
$365.20
Details
Rat Rabbit Un-conjugated ICC, IHC (fro), IHC (p), ELISA, WB 100 μg Log in to see 9 to 11 Days
$396.00
Details
Human Rabbit Alkaline Phosphatase (AP) ELISA, WB   200 μL Log in to see 8 to 10 Days
$969.83
Details
Human Rabbit Un-conjugated WB 400 μL Log in to see 6 Days
$457.14
Details
Mouse Sheep Un-conjugated ELISA, WB   100 μg Log in to see 8 to 10 Days
$969.83
Details
Human Rabbit APC ELISA, WB   200 μL Log in to see 8 to 10 Days
$969.83
Details

MEPE Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Human , ,


, , , , , , , , , , , , , ,
Rat (Rattus) ,


,
Mouse (Murine)


Top referenced anti-MEPE Antibodies

  1. Human Polyclonal MEPE Primary Antibody for EIA, WB - ABIN953388 : Boskey, Chiang, Fermanis, Brown, Taleb, David, Rowe: MEPE's diverse effects on mineralization. in Calcified tissue international 2010 (PubMed)
    Show all 5 references for ABIN953388

More Antibodies against MEPE Interaction Partners

Human Matrix Extracellular phosphoglycoprotein (MEPE) interaction partners

  1. Results indicate an association of MEPE gene inactivation with decreased survival after DNA damage.

  2. Mice deficient in an ortholog of MEPE show increased bone mass and are resistant to aging-related bone loss.

  3. results indicated that MEPE appeared to play an important positive role in proliferation and osteogenesis differentiation of DPCs through interaction with downstream signals.

  4. MEPE or the MEPE-derived acidic serine aspartate-rich MEPE-associated motif peptide may contribute to decreased bone mineralization in Oncogenic osteomalacia patients.

  5. Among migraineurs with aura (show AURKA Antibodies) rs7698623 in MEPE (OR = 6.37; 95% CI 3.15-12.90; p = 2.7x10(-7)) and rs4975709 in IRX4 (show IRX4 Antibodies) (OR = 5.06; 95% CI 2.66-9.62; p = 7.7x10(-7)) appeared to be associated with ischemic stroke.

  6. Sclerostin (show SOST Antibodies) acts through regulation of the PHEX (show PHEX Antibodies)/MEPE axis at the preosteocyte stage and serves as a master regulator of physiologic bone mineralization.

  7. MEPE may play a regulatory role in periodontal ligament cell osteogenic differentiation.

  8. These results suggest that abnormal MEPE cleavage occurs when PHEX (show PHEX Antibodies) activity is deficient in humans.

  9. This study demonstrates the importance of posttranslational modification for the site-specific activity of MEPE and its ASARM peptide.

  10. The patterns of expression of FGF-23 (show FGF23 Antibodies), MEPE, and DMP1 (show DMP1 Antibodies) differ markedly in trabecular bone, suggesting that individual osteocytes may have specialized functions.

Mouse (Murine) Matrix Extracellular phosphoglycoprotein (MEPE) interaction partners

  1. Mepe(-/-) molars exhibited increased thickness of predentin, dentin, and enamel over controls and decreased gene expression of Enam (show ENAM Antibodies), Bsp (show KLK6 Antibodies), Dmp1 (show DMP1 Antibodies), Dspp (show DSPP Antibodies), and Opn (show SPP1 Antibodies) by RT-PCR.

  2. An in situ hybridization study of perlecan (show HSPG2 Antibodies), DMP1 (show DMP1 Antibodies), and MEPE in developing condylar cartilage of the fetal mouse mandible and limb bud cartilage.

  3. MEPE is an important regulator of growth plate chondrocyte matrix mineralization through its cleavage to an ASARM peptide.

  4. The temporal-spatial specific pattern and unique co-localization of Dspp (show DSPP Antibodies), Mepe, Mimecan (show OGN Antibodies) and Versican (show Vcan Antibodies) suggest they play complementary roles during odontogenesis.

  5. Wnt3a (show WNT3A Antibodies) stimulates Mepe transcription directly by a canonical Wnt (show WNT2 Antibodies) signaling pathway through beta-catenin (show CTNNB1 Antibodies) and Lef-1 (show LEF1 Antibodies) and indirectly through the activation of a Bmp-2 (show BMP2 Antibodies) autocrine loop.

  6. MEPE might be an important signaling molecule involved in the regulation of osteoblast and osteoclast activity during bone remodeling.

  7. the C-terminal fragment of MEPE containing an RGD sequence, cleaved in odontoblasts, appeared to be the active form of MEPE, which may play important roles in dentinogenesis and pulpal homeostasis by keeping the odontoblasts in immature condition.

  8. MEPE may be involved in the pathogenesis defective mineralization due to Phex (show PHEX Antibodies) deficiency in X-linked hypophosphatemia (XLH (show PHEX Antibodies)) and the Hyp (show PHEX Antibodies)-mouse.

  9. Mepe appears to play a role in both long bone regeneration and the latter stages of skeletogenesis.

  10. degradation of MEPE and DMP-1 (show DMP1 Antibodies) and release of ASARM peptides are chiefly responsible for the HYP (show PHEX Antibodies) mineralization defect and changes in osteoblast-osteoclast differentiation.

MEPE Antigen Profile

Protein Summary

may play a role in bone homeostasis

Gene names and symbols associated with MEPE

  • matrix extracellular phosphoglycoprotein (MEPE) antibody
  • matrix extracellular phosphoglycoprotein (Mepe) antibody
  • matrix extracellular phosphoglycoprotein (LOC789774) antibody
  • matrix extracellular phosphoglycoprotein with ASARM motif (bone) (Mepe) antibody
  • matrix extracellular phosphoglycoprotein-like (LOC100521206) antibody
  • OC-116 antibody
  • Of45 antibody

Protein level used designations for MEPE

matrix extracellular phosphoglycoprotein , matrix, extracellular phosphoglycoprotein with ASARM motif (bone) , matrix, extracellular phosphoglycoprotein with ASARM motif (bone)-like , matrix extracellular phosphoglycoprotein-like , osteoblast/osteocyte factor 45 , matrix extracellular phosphoglycoprotein with ASARM motif (bone) , osteoregulin , ovocleidin-116 , ovocleidin-116 protein , matrix extracellular phosphoglycoprotein with ASARM motif

GENE ID SPECIES
471250 Pan troglodytes
613958 Bos taurus
701943 Macaca mulatta
100395421 Callithrix jacchus
100423048 Equus caballus
100423049 Felis catus
100432487 Pongo abelii
100581372 Nomascus leucogenys
56955 Homo sapiens
79110 Rattus norvegicus
100715513 Cavia porcellus
487851 Canis lupus familiaris
789774 Bos taurus
101120244 Ovis aries
395256 Gallus gallus
94111 Mus musculus
100521206 Sus scrofa
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