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Matrix Metallopeptidase 11 (Stromelysin 3) Proteins (MMP11)

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Additionally we are shipping MMP11 Antibodies (125) and MMP11 Kits (47) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
MMP11 17385 Q02853
MMP11 25481 Q499S5
MMP11 4320 P24347
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Top MMP11 Proteins at antibodies-online.com

Showing 10 out of 11 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His-GST 10% SDS-PAGE stained with Coomassie Blue (CB) and peptide fingerprinting by MALDI-TOF mass spectrometry 50 μg Log in to see 5 to 7 Days
$358.05
Details
HOST_Escherichia coli (E. coli) Human His tag 100 μg Log in to see 11 to 13 Days
$616.00
Details
HOST_Escherichia coli (E. coli) Rat His tag,S tag 100 μg Log in to see 11 to 13 Days
$950.40
Details
HOST_Escherichia coli (E. coli) Mouse His tag   100 μg Log in to see 11 to 13 Days
$739.20
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$3,076.33
Details
Yeast Xenopus laevis His tag   1 mg Log in to see 56 to 66 Days
$3,081.83
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   100 μg Log in to see 9 to 19 Days
$794.65
Details
HOST_Escherichia coli (E. coli) Mouse Un-conjugated   100 μg Log in to see 9 to 19 Days
$920.54
Details

MMP11 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)

Rat (Rattus) ,
,
Human
,

More Proteins for Matrix Metallopeptidase 11 (Stromelysin 3) (MMP11) Interaction Partners

Mouse (Murine) Matrix Metallopeptidase 11 (Stromelysin 3) (MMP11) interaction partners

  1. Results show that MMP-11 has a paracrine function during mammary gland development that might be harnessed to promote tumor progression, exposing a new link between development and malignancy.

  2. point-out the paradoxical role of MMP11 in favoring the onset and growth of lung metastases but limiting lung foci number, and inhibiting the cancer cell dissemination to other organs

  3. investigation of a potential role of MMP-11 in adipose tissue development

  4. The increased levels of ST-3 in the thymus may be due to the presence of macrophages responsible for clearance of apoptotic cells

  5. downregulated by deglycosylation of CD147 (show BSG Proteins) in hepatocarcinoma cells

  6. These data together provide compelling evidence into the function of MMP-11 and suggest that MMP-11 act as a tumor lymphatic metastasis-associated gene.

  7. These findings reveal that the tumor biological marker CD147 (show BSG Proteins) functionally mediates MMP-11, VEGF-A (show VEGFA Proteins) expression and tumor lymphatic metastasis.

  8. Mmp11 exhibits collagenolytic function against collagen VI under normal conditions.

  9. Our study describes the identification of MMP11 as a novel broadly expressed tumor associated antigen as target candidate for cancer immunotherapy.

Human Matrix Metallopeptidase 11 (Stromelysin 3) (MMP11) interaction partners

  1. Matrix metalloproteinase 11 has a role in degenerating intervertebral disc disease

  2. combined effects of the MMP-11 gene polymorphisms and environmental carcinogens are related to an increased risk for the development of OSCC and may be a predictive factor for tumor lymph node metastasis in Taiwanese with OSCC

  3. results indicated that both CD147 (show BSG Proteins) and MMP-11 may be involved in the progression of colorectal cancer, and they are potential prognostic factors and might become new therapeutic targets for CRC (show CALR Proteins) patients

  4. High Expression of Matrix Metalloproteinase-11 is associated with Cholangiocarcinoma.

  5. study showed that plasma level of MMP-11 may be useful for assessment of the disease progression, especially lymph node metastasis, in patients with OSCC

  6. MMP-14 (show MMP14 Proteins) function might represent one critical regulatory mechanism to control the extent of pericellular MMP-11 bioavailability and protect cells from excessive/inappropriate MMP-11 function.

  7. These findings further suggest MMP11 as a promising biomarker for breast and prostate cabcer.

  8. MMP-11 expression was significantly related to clinicopathological parameters, which may be essential to the prediction of disease outcome in patients with invasive ductal carcinoma of the breast.

  9. Knockdown of MMP11 expression could inhibit the proliferation and invasion of gastric adenocarcinoma cells probably through down-regulation of the IGF-1 (show IGF1 Proteins) signaling pathway.

  10. Findings define a regulatory role of miR (show MLXIP Proteins)-98 in tumor angiogenesis and invasion through repressed ALK4 (show ACVR1B Proteins) and MMP11 expression.

Xenopus laevis Matrix Metallopeptidase 11 (Stromelysin 3) (MMP11) interaction partners

  1. Transgenic tadpoles were prepared with an elastase promoter driving either the ST3 gene or the constitutively active form of Notch (show NOTCH1 Proteins) (IC).

  2. analysis of substrate specificity for stromelysin-3: alpha1-PI is unlikely to be a physiological substrate

  3. ST3 regulates cell fate and tissue morphogenesis through direct or indirect extracellular matrix remodeling

  4. Laminin receptor precursor cleavage by ST3 plays a role in both physiological and pathological processes.

  5. thyroid hormone (show PTH Proteins) regulation of Xenopus laevis Stromelysin-3 is mediated by a DNA element in the first intron

  6. Mutational analysis of the cleavage of the cancer-associated laminin receptor by stromelysin-3 reveals the contribution of flanking sequences to site recognition and cleavage efficiency.

  7. ST3 expression, in the absence of T3 hormone, caused significant muscle cell death in the tail of premetamorphic transgenic tadpoles

MMP11 Protein Profile

Protein Summary

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the enzyme encoded by this gene is activated intracellularly by furin within the constitutive secretory pathway. Also in contrast to other MMP's, this enzyme cleaves alpha 1-proteinase inhibitor but weakly degrades structural proteins of the extracellular matrix.

Gene names and symbols associated with MMP11

  • matrix metallopeptidase 11 (Mmp11)
  • matrix metallopeptidase 11 (stromelysin 3) (MMP11)
  • matrix metallopeptidase 11 (stromelysin 3) (Mmp11)
  • matrix metallopeptidase 11 (stromelysin 3) (mmp11)
  • matrix metalloproteinase 11 (LOC100101604)
  • SL-3 protein
  • ST3 protein
  • STMY3 protein

Protein level used designations for MMP11

MMP-11 , SL-3 , matrix metalloproteinase 11 , matrix metalloproteinase-11 , stromelysin 3 , stromelysin-3 , Matrix metalloproteinase 11 (stromelysin 3) , stromelysin III , ST3 , gene 14

GENE ID SPECIES
17385 Mus musculus
25481 Rattus norvegicus
4320 Homo sapiens
486408 Canis lupus familiaris
100153503 Sus scrofa
100713229 Cavia porcellus
379501 Xenopus laevis
100101604 Oryctolagus cuniculus
539109 Bos taurus
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