Matrix Metallopeptidase 12 (Macrophage Elastase) Proteins (MMP12)

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Additionally we are shipping MMP12 Antibodies (178) and MMP12 Kits (57) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
MMP12 17381 P34960
MMP12 117033 Q63341
MMP12 4321 P39900
How to order from antibodies-online
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Order online
  • orders@antibodies-online.com

Top MMP12 Proteins at antibodies-online.com

Showing 10 out of 34 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 30 to 35 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 30 to 35 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Rabbit His tag 100 μg Log in to see 15 to 18 Days
$848.00
Details
HOST_Human Human His tag   10 μg Log in to see 15 to 16 Days
$300.00
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 11 to 12 Days
$405.71
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated 100 μg Log in to see 20 to 21 Days
$437.80
Details
HOST_Mammalian Cells Mouse His tag   50 μg Log in to see 4 Days
$548.63
Details
HOST_Escherichia coli (E. coli) Human His tag   50 μg Log in to see 11 Days
$341.00
Details
HOST_Escherichia coli (E. coli) Human His tag 100 μg Log in to see 15 to 18 Days
$768.00
Details
HOST_Escherichia coli (E. coli) Mouse His tag 100 μg Log in to see 15 to 18 Days
$832.00
Details

MMP12 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine) , ,

Rat (Rattus) ,

Human , ,
,

More Proteins for Matrix Metallopeptidase 12 (Macrophage Elastase) (MMP12) Interaction Partners

Mouse (Murine) Matrix Metallopeptidase 12 (Macrophage Elastase) (MMP12) interaction partners

  1. Mmp12 is expressed early following corneal epithelial injury with highest expression levels at 8 h after injury and lower expression levels at 4 and 8 days after injury. We investigated whether MMP12 has an effect on the rate of epithelial repair and cell migration using in vivo and in vitro scratch assays performed on WT and Mmp12(-/-) mice

  2. MMP-12 produced by macrophages infiltrating into glomeruli contributed to the degradation of collagen type IV (show COL4 Proteins) and fibronectin (show FN1 Proteins).

  3. MMP12 causes arterial stiffening in mice and suggest that it functions similarly in humans.

  4. These results suggest that MMP-12 production during emphysema exacerbation results in increased mortality and disease progression.

  5. study found significant increases of MMP-3 (show MMP3 Proteins) and MMP-12 mRNA levels and MMP12 zymographic activities in response to Cryptococcus neoformans infection but not C. gattii infection

  6. The results suggest that pulmonary C fiber involvement in long-term airway inflammation and airway hyperresponsiveness occurred at least partially via modulating MMP-12, and the activation of PAR2 (show F2RL1 Proteins) might be related to MMP-12 production.

  7. MMP-12 up-regulation mediated by SARM (show SARM1 Proteins)-TRIF (show RNF138 Proteins) signaling pathway contributes to IFN-gamma (show IFNG Proteins)-independent airway inflammation and AHR (show AHR Proteins) post RSV infection in nude mice.

  8. MMP-12 and MMP-13 (show MMP13 Proteins) alter strain K infection in mice and play a role in inflammatory regulation by modulating cytokine levels.

  9. Post-MI, MMP-12i impaired CD44 (show CD44 Proteins)-HA interactions to suppress neutrophil apoptosis and prolong inflammation, which worsened LV function.

  10. MMP12 upregulated in regenerating motor neurons of the mouse and rat facial nucleus; findings point to a role of MMP12 in the neuronal initiation of the synaptic stripping process

Human Matrix Metallopeptidase 12 (Macrophage Elastase) (MMP12) interaction partners

  1. Data indicate that MMP1 (show MMP1 Proteins), MMP12 and PPARG (show PPARG Proteins) and hsa (show CD24 Proteins)-miR (show MLXIP Proteins)-31-5p, hsa (show CD24 Proteins)-miR (show MLXIP Proteins)-224-5p, and hsa (show CD24 Proteins)-miR (show MLXIP Proteins)-223-3p were able to distinguish tumors from NPT with high sensitivity and specificity.

  2. Increased levels of MMP1 (show MMP1 Proteins) and MMP12 on tumor-associated macrophages in the peripheral areas of dermatofibrosarcoma protuberance might contribute to local invasion

  3. Matrix metalloprotease (show ADAM8 Proteins) (MMP) regulation was the top pathway involved in gingival aging. MMP3 (show MMP3 Proteins), MMP9 (show MMP9 Proteins), MMP12, and MMP13 (show MMP13 Proteins) were upregulated in old gingival tissues, concomitantly with interleukin-1 beta (IL1B (show IL1B Proteins)) expression.

  4. We also found that MMP12 facilitated type I collagen induced platelet aggregation, adhesion and alpha granule secretion. Similarly, one short peptide, WYKG, facilitated type I collagen induced platelet alpha granule secretion. We conclude that platelet express MMP12 may facilitate platelet activation through shedding of CEACAM1 (show CEACAM1 Proteins).

  5. There were no statistically significant differences in the distribution of MMP7 (show MMP7 Proteins) -181 A/G and MMP12 -82 A/G genotype, allele, or haplotype frequencies between IRSA patients and controls, as well as patients' primary and secondary idiopathic recurrent spontaneous abortion

  6. To conclude, Pseudomonas aeruginosa infection induced the expression of matrix metalloproteinases, and Pseudomonas aeruginosa type III secretion system appeared to be a key player in MMP-12 and MMP-13 (show MMP13 Proteins) expression, which is further controlled by NF-kappaB (show NFKB1 Proteins) signaling.

  7. This study demonstrated that the MMP-12 levels was significantly higher in patients with atheromatous plaques than in those without plaques.

  8. High MMP12 expression is associated with gastric cancer.

  9. Study evaluated MMP-12 and TIMP-1 (show TIMP1 Proteins), TIMP-2 (show TIMP2 Proteins), TIMP-3 (show TIMP3 Proteins), and TIMP-4 (show TIMP4 Proteins) levels in 40 patients with asymptomatic and symptomatic critical carotid artery stenosis (CAS (show CSE1L Proteins)) with neurologic symptoms onset within the preceding 12 hours; results suggest that MMP-12 is related to critical CAS (show CSE1L Proteins) independently on symptoms, moreover, TIMP-3 (show TIMP3 Proteins) and TIMP-4 (show TIMP4 Proteins) seem to be specifically related to stroke

  10. MMP12 causes arterial stiffening in mice and suggest that it functions similarly in humans.

Rabbit Matrix Metallopeptidase 12 (Macrophage Elastase) (MMP12) interaction partners

  1. Gene expression profiling performed on tissues obtained from pulmonary sarcoidosis patients identified MMP12 as a potential pathogenic mediator of lung damage and/or remodeling and may serve as a marker for this disease.

MMP12 Protein Profile

Protein Summary

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. It is thought that the protein encoded by this gene is cleaved at both ends to yield the active enzyme, but this processing has not been fully described. The enzyme degrades soluble and insoluble elastin. It may play a role in aneurysm formation and studies in mice suggest a role in the development of emphysema. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3.

Gene names and symbols associated with MMP12

  • matrix metallopeptidase 12 (macrophage elastase) (MMP12)
  • matrix metallopeptidase 12 (Mmp12)
  • AV378681 protein
  • HME protein
  • ME protein
  • MME protein
  • Mmel protein
  • MMP-12 protein
  • MMP12 protein

Protein level used designations for MMP12

matrix metallopeptidase 12 (macrophage elastase) , matrix metalloproteinase 12 , MME , MMP-12 , macrophage elastase , macrophage metalloelastase , macrophage-metalloelastase , matrix metalloproteinase-12 , matrix metalloproteinase 12 (macrophage elastase) , macrophage metalloelastase MMP-12

GENE ID SPECIES
451512 Pan troglodytes
17381 Mus musculus
117033 Rattus norvegicus
4321 Homo sapiens
100009559 Oryctolagus cuniculus
611789 Canis lupus familiaris
526981 Bos taurus
Selected quality suppliers for MMP12 Proteins (MMP12)
Did you look for something else?