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MMP21 (MMP23B) encodes a member of the matrix metalloproteinase (MMP) family, and it is part of a duplicated region of chromosome 1p36.3. Additionally we are shipping Matrix Metallopeptidase 21 Antibodies (13) and Matrix Metallopeptidase 21 Kits (2) and many more products for this protein.
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loss of MMP21 as a cause of heterotaxy in humans with concomitant defects in Notch (show NOTCH1 Proteins) signaling.
Data show that MMP21 (encoding matrix metallopeptidase 21) point mutations were verified by Sanger sequencing, and segregation analysis indicated recessive inheritance.
Increased MMP-21 expression in esophageal squamous cell carcinoma is associated with progression and lymph node metastasis.
These results suggest that high MMP-21 expression in lymph node metastatic foci can be used to predict survival in OSCC patients with LNM
analysis proved MMP-21 to be an independent prognostic factor for overall survival of gastric cancer patients
MMP-21 expression is elevated in primary CRC (show CALR Proteins) and related to tumor invasion and metastasis. MMP-21 was also proved to be an independent prognostic factor for patients with stage II and stage III colorectal cancer.
MMP-21 does not associate with invasion of squamous cell cancer but may be involved in keratinocyte differentiation.
MMP-21 was expressed by Merkel cell carcinoma cells in 13/43 cases and in eight samples by stromal neutrophils. None of the samples with MMP-21-expressing neutrophils had metastasized to the lymph nodes
The MMP-21 gene 572C/T polymorphism has no significant effect on the development and progression of breast cancer.
During esophageal tumorigenesis, MMP-21 and MMP-26 have different, unique expression patterns.
MMP-21 (show MMP24 Proteins) does not associate with invasion of squamous cell cancer but may be involved in keratinocyte differentiation.
This gene encodes a member of the matrix metalloproteinase family. Proteins in this family are involved in the breakdown of extracellular matrix for both normal physiological processes, such as embryonic development, reproduction, and tissue remodeling,and disease processes, such as asthma and metastasis. The encoded protein may play an important role in embryogenesis, particularly in neuronal cells, as well as in lymphocyte development and survival.
matrix metalloproteinase 21
, matrix metalloproteinase-21
, matrix metallopeptidase-21
, matrix metallopeptidase 23A (pseudogene)
, LOW QUALITY PROTEIN: matrix metalloproteinase-21