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Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as art. Additionally we are shipping Matrix Metallopeptidase 25 Kits (15) and and many more products for this protein.
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Human Monoclonal MMP25 Primary Antibody for CyTOF, FACS - ABIN4900198
Zhao, Sohail, Sun, Shi, Kim, Mobashery, Fridman: Identification and role of the homodimerization interface of the glycosylphosphatidylinositol-anchored membrane type 6 matrix metalloproteinase (MMP25). in The Journal of biological chemistry 2008
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Results suggest a crucial role of MMP9 (show MMP9 Antibodies) at the early stage of carcinogenesis in the large intestine. The increase in MMP9 (show MMP9 Antibodies) and TIMP1 (show TIMP1 Antibodies) mRNA concentration and the decrease in MMP28 (show MMP28 Antibodies) in the large intestinal tissue may be a confirmation of cancer.
These results proved for the first time that epilysin (show MMP28 Antibodies) expression was significantly elevated in glioblastoma
A decreased level of IL-33 (show IL33 Antibodies) and an elevated concentration of MMP-28 (show MMP28 Antibodies) were found in coronary heart disease patients and correlated with disease severity.
In absolute mRNA levels, significant differences were found in expression of MMP2, MMP24, and MMP25 in gastric carcinoma compared with superficial gastritis.
MMP28 (show MMP28 Antibodies) mRNA expression is highest in healthy tissues when compared to diseased periodontal tissues.
IL-2 (show IL2 Antibodies)-upregulated MT6 (show PRSS33 Antibodies) cell-surface expression correlates with CD16 (show CD16 Antibodies) downmodulation. MT6 (show PRSS33 Antibodies), sequestered in intracellular compartments in unstimulated NK cells, translocates to the effector-target cell interface of CD16 (show CD16 Antibodies)-mediated immunological synapses.
Data established a seven-gene (AR, ESR2 (show ESR2 Antibodies), GATA3 (show GATA3 Antibodies), GBX2 (show GBX2 Antibodies), KRT16 (show KRT16 Antibodies), MMP28 (show MMP28 Antibodies) and WNT11 (show WNT11 Antibodies)) prognostic signature to define a subset of triple-negative breast cancer (TNBC).
Inhibition of BCMO1 (show BCMO1 Antibodies) expression is associated with increased invasiveness of colon cancer cells and increased expression of MMP7 (show MMP7 Antibodies) and MMP28 (show MMP28 Antibodies). beta-Carotene can upregulate BCMO1 (show BCMO1 Antibodies) and reverse these effects.
Over-expression of MMP28 provides protection against apoptosis induced by either serum-deprivation or treatment with a protein kinase inhibitor.
MT6-MMP regulates neutrophil and monocyte chemotaxis and by generating "eat-me" signals upon vimentin (show VIM Antibodies) cleavage potentially increases phagocytic removal of neutrophils to resolve inflammation.
this study shows that Mmp25-null mice exhibit a defective innate immune response characterized by low sensitivity to bacterial LPS (show TLR4 Antibodies), hypergammaglobulinemia, and reduced secretion of proinflammatory molecules
These data suggest MMP-25 is a direct transcriptional target for TGF-beta3 (show TGFB3 Antibodies) in mouse secondary palate development and could be a target for TGF-beta3 (show TGFB3 Antibodies) elsewhere as well.
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix for both normal physiological processes, such as embryonic development, reproduction and tissue remodeling, and disease processes, such as asthma and metastasis. This gene encodes a secreted enzyme that degrades casein. Its expression pattern suggests that it plays a role in tissue homeostasis and in wound repair. Transcript variants encoding different isoforms have been described.
, matrix metallopeptidase-like 1
, matrix metalloproteinase 20
, matrix metalloproteinase 25
, matrix metalloproteinase-25
, matrix metalloproteinase-like 1
, membrane-type 6 matrix metalloproteinase
, membrane-type matrix metalloproteinase 6
, membrane-type-6 matrix metalloproteinase
, matrix metalloproteinase 28
, matrix metalloproteinase-28