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Matrix Metallopeptidase 3 (Stromelysin 1, Progelatinase) Proteins (MMP3)

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Additionally we are shipping Matrix Metallopeptidase 3 (Stromelysin 1, Progelatinase) Antibodies (377) and Matrix Metallopeptidase 3 (Stromelysin 1, Progelatinase) Kits (141) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
MMP3 17392 P28862
MMP3 171045  
MMP3 4314 P08254
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Top Matrix Metallopeptidase 3 (Stromelysin 1, Progelatinase) Proteins at antibodies-online.com

Showing 10 out of 51 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human Un-conjugated 100 μg Log in to see 16 Days
$822.80
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_HEK-293 Human Un-conjugated   10 μg Log in to see 10 to 12 Days
$206.55
Details
HOST_HEK-293 Mouse Un-conjugated   10 μg Log in to see 10 to 12 Days
$206.55
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag 50 μg Log in to see 21 to 26 Days
$341.00
Details
HOST_Escherichia coli (E. coli) Human His-SUMO Tag 50 μg Log in to see 21 to 26 Days
$341.00
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated 10 μg Log in to see 5 to 6 Days
$440.82
Details
HOST_Escherichia coli (E. coli) Rat His tag,T7 tag 100 μg Log in to see 11 to 13 Days
$704.00
Details
HOST_Escherichia coli (E. coli) Human His tag,T7 tag 100 μg Log in to see 11 to 13 Days
$788.70
Details

MMP3 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine) ,
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Rat (Rattus) ,
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Human , , , , ,
, , ,

Top referenced Matrix Metallopeptidase 3 (Stromelysin 1, Progelatinase) Proteins

  1. Mouse (Murine) MMP3 Protein expressed in HEK-293 - ABIN2666509 : Gill, Parks: Metalloproteinases and their inhibitors: regulators of wound healing. in The international journal of biochemistry & cell biology 2008 (PubMed)
    Show all 8 references for ABIN2666509

  2. Human MMP3 Protein expressed in HEK-293 - ABIN2666507 : Herath, Wang, Seneviratne, Darveau, Wang, Jin: The expression and regulation of matrix metalloproteinase-3 is critically modulated by Porphyromonas gingivalis lipopolysaccharide with heterogeneous lipid A structures in human gingival fibroblasts. in BMC microbiology 2013 (PubMed)
    Show all 7 references for ABIN2666507

  3. Human MMP3 Protein expressed in Escherichia coli (E. coli) - ABIN2002905 : Sternlicht, Lochter, Sympson, Huey, Rougier, Gray, Pinkel, Bissell, Werb: The stromal proteinase MMP3/stromelysin-1 promotes mammary carcinogenesis. in Cell 1999 (PubMed)

More Proteins for Matrix Metallopeptidase 3 (Stromelysin 1, Progelatinase) (MMP3) Interaction Partners

Mouse (Murine) Matrix Metallopeptidase 3 (Stromelysin 1, Progelatinase) (MMP3) interaction partners

  1. NMP4 (show ZNF384 Proteins) deficiency suppressed the arthritis-induced increase in bone resorption, expression of RANKL (show TNFSF11 Proteins) and MMP-3 mRNA.

  2. MMP-3 produced in blood vessel endothelial cells after spinal cord injury serves as an endogenous molecule for microglial activation followed by p38MAPK (show MAPK14 Proteins) activation and proNGF production

  3. genetic inactivation of MMP-3 has profound effects on the structural integrity and plasticity response of the visual cortex of adult mice

  4. study found significant increases of MMP-3 and MMP-12 (show MMP12 Proteins) mRNA levels and MMP12 (show MMP12 Proteins) zymographic activities in response to Cryptococcus neoformans infection but not C. gattii infection

  5. This study demonstrates the sequential involvement of Wnt5, MMP-3, DMP-1 expression, and DMP-1 degradation products by MMP-3, in effecting IL-1beta-induced proliferation of ESC-derived odontoblast-like cells.

  6. Study suggests that MMP-3 modulates intracellular MAP kinase (show MAPK1 Proteins) signaling pathway and as such, influences a molecular chaperone (show HSP90AA1 Proteins) that regulates cytoskeletal components important for neurite outgrowth, neuronal migration and dendritic arborization

  7. Data indicate that interferon regulatory factor-8 (IRF8 (show IRF8 Proteins)) regulates tumor behavior in an matrix metalloproteinase 3 (MMP3)-dependent manner.

  8. Established are novel molecular mechanisms underlying oxidative stress-mediated dopaminergic neuronal death in which MMP3 activation is a key upstream event that leads to Nox1 (show NOX1 Proteins) induction and eventual dopaminergic neuronal death.

  9. Our findings suggest that increased numbers of CD11c (show ITGAX Proteins)(+) macrophages and elevated levels of TNF-alpha (show TNF Proteins) and MMP-3 in AT and ST may explain the relationship between hyperlipidaemia and OA.

  10. These results demonstrated the role of MMP-3 in blood-spinal cord disruption after spinal cord injury for the first time

Human Matrix Metallopeptidase 3 (Stromelysin 1, Progelatinase) (MMP3) interaction partners

  1. These results indicate an essential role for MAPKs in the induction of MMP-3 in synovial sarcoma cells, through AP-1 (show FOSB Proteins) activation.

  2. A low level of MMP-3 is an excellent positive predictor for polymyalgia rheumatica with giant cell arteritis.

  3. These results demonstrated widespread alterations of matrix metalloproteinase 3 expression in Multiple System Atrophy.

  4. MMP-3 haplotypes association with susceptibility and severity of juvenile idiopathic arthritis

  5. increased serum MMP-3 level correlates with the development of AS, suggesting that MMP-3 may present a clinical value in reflecting the progression of AS.

  6. MMP-3 is associated with the occurrence and development of RA bone erosion, and its serum level and mRNA expression can be treated as important predictors of joint damage.

  7. new evidence that promoter polymorphisms in MMP3 are functional and may affect gene transcription with possible effects on craniofacial development leading to NSCL (show NHLH1 Proteins)/P.

  8. Elevated levels of MMP-3 are associated with an increased risk of long-term MI in patients with and without ACS referred for coronary angiography.

  9. MMP3 rs522616 in the promoter region was significantly associated with coal workers' pneumoconiosis

  10. The MMP-3-1612 5A/6A polymorphism may effect serum MMP-3 level and over-expression of serum MMP-3 level may be a risk factor for DVT formation.

Pig (Porcine) Matrix Metallopeptidase 3 (Stromelysin 1, Progelatinase) (MMP3) interaction partners

  1. The present study was aimed to determine the association between metalloproteinase 3 (MMP3), transforming growth factor beta 1 (TGFbeta1 (show TGFB1 Proteins)) and collagen type X alpha I (COL10A1 (show COL10A1 Proteins)) gene polymorphisms with traits related to leg weakness in pigs.

  2. the identification of MMP1 (show MMP1 Proteins) and MMP10 (show MMP10 Proteins) genes in swine is reported.

  3. contribution of MMPs to the inflammatory breakdown of the blood-CSF (show CSF2 Proteins) barrier in vitro

  4. Results indicate that leukemia inhibitory factor (LIF (show LIF Proteins)) and Oncostatin M (show OSM Proteins) increase the expression of MMP-1 (show MMP1 Proteins), MMP-3, and TIMP-1 (show TIMP1 Proteins) several fold, and that their expression is reduced to basal levels in the presence of the LIF (show LIF Proteins) antagonist MH35-BD.

Rabbit Matrix Metallopeptidase 3 (Stromelysin 1, Progelatinase) (MMP3) interaction partners

  1. chitosan-pDNA nanoparticles encoding shRNA targeting MMP-3 and -13 had great potential in silencing the dedifferentiation-related genes for regenerating prolonged and endurable cartilage.

  2. Ulinastatin (show AMBP Proteins) effectively inhibited the increased expression of MMP-2 (show MMP2 Proteins), MMP-3, and iNOS (show NOS2 Proteins) in degenerated NP cells induced by IL-1beta (show IL1B Proteins) in vitro.

  3. Tongxinluo can inhibit the expression of MMP-3 and 9 and increase the expression of PPARgamma (show PPARG Proteins) in atherosclerotic rabbits.

Matrix Metallopeptidase 3 (Stromelysin 1, Progelatinase) (MMP3) Protein Profile

Protein Summary

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This gene encodes an enzyme which degrades fibronectin, laminin, collagens III, IV, IX, and X, and cartilage proteoglycans. The enzyme is thought to be involved in wound repair, progression of atherosclerosis, and tumor initiation. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3.

Gene names and symbols associated with MMP3

  • matrix metallopeptidase 3 (Mmp3)
  • matrix metallopeptidase 3 (stromelysin 1, progelatinase) (MMP3)
  • matrix metallopeptidase 3 (stromelysin 1, progelatinase) (Mmp3)
  • matrix metallopeptidase 10 (stromelysin 2) (MMP10)
  • CHDS6 protein
  • MMP-3 protein
  • MMP3 protein
  • MMP10 protein
  • SL-1 protein
  • SLN-1 protein
  • SLN1 protein
  • STMY protein
  • STMY1 protein
  • STR-1 protein
  • STR1 protein

Protein level used designations for MMP3

EMS-2 , MMP-3 , SL-1 , matrix metalloproteinase 3 , matrix metalloproteinase-3 , progelatinase , stromelysin 1 , stromelysin-1 , transin-1 , PTR1 protein , matrix metalloproteinase 3 (stromelysin 1, progelatinase) , proteoglycanase , stromelysin , metalloproteinase 3 receptor , matrix metallopeptidase 3 (stromelysin 1, progelatinase) , matrix metalloproteinase 10 (stromelysin 2)

GENE ID SPECIES
17392 Mus musculus
171045 Rattus norvegicus
4314 Homo sapiens
396769 Sus scrofa
100009111 Oryctolagus cuniculus
281309 Bos taurus
403445 Canis lupus familiaris
100034195 Equus caballus
100729101 Cavia porcellus
101118895 Ovis aries
418981 Gallus gallus
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