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anti-Matrix Metallopeptidase 3 (Stromelysin 1, Progelatinase) (MMP3) Antibodies

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as art. Additionally we are shipping Matrix Metallopeptidase 3 (Stromelysin 1, Progelatinase) Kits (139) and Matrix Metallopeptidase 3 (Stromelysin 1, Progelatinase) Proteins (53) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
MMP3 17392 P28862
MMP3 171045  
MMP3 4314 P08254
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Top anti-Matrix Metallopeptidase 3 (Stromelysin 1, Progelatinase) Antibodies at antibodies-online.com

Showing 10 out of 381 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Mouse Un-conjugated EIA, IHC (p), WB 0.2 mg Log in to see 6 to 8 Days
$368.50
Details
Dog Rabbit Un-conjugated IHC, WB WB Suggested Anti-MMP3 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:1562500Positive Control: Jurkat cell lysate Sample Type: 1. Normal HUman Cartilage (50ug)2. Human Osteoarthritis cartilage (50ug)3. Human Osteoarthritis chondrocytes (50ug)4. Human Osteoarthritis chondrocytes +IL-1 (50ug)Primary Dilution: 1:2000Secondary Antibody: HRP conjugated anti-rabbitSecondary Dilution: 1:5000Image Submitted By: Mukundan AtturNYU Hospital for Joint Disease 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Horse Rabbit Un-conjugated WB Western blot analysis of MMP-3 expression with Jurkat cell lysate. Both full length (55 kDa)  and cleaved form (21 kDa) can be detected. 100 μg Log in to see 2 to 3 Days
$283.50
Details
Human Rabbit Un-conjugated IF, IHC (p), WB MMP3 Antibody (N-term) (ABIN657459) western blot analysis in NCI-H460 cell line lysates (35 µg/lane). This demonstrates the MMP3 antibody detected the MMP3 protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated FACS, IHC (p), WB Western blot analysis of MMP3 (arrow) using rabbit polyclonal MMP3 Antibody (Center) (ABIN390151). 293 cell lysates (2 µg/lane) either nontransfected (Lane 1) or transiently transfected with the MMP3 gene (Lane 2) (Origene Technologies). Formalin-fixed and paraffin-embedded human hepatocarcinoma reacted with MMP3 Antibody (Center), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Mouse Un-conjugated FACS, ICC, IHC, WB Detection of MMP-3 in MG-63 Human Cell Line by Flow Cytometry. MG-63 human osteosarcoma cell line was stained with Mouse Anti-Human MMP-3 Monoclonal Antibody. MMP-3 in Human Prostate and Human Prostate Cancer Tissue. MMP-3 was detected in immersion fixed paraffin-embedded sections of normal human prostate and human prostate cancer tissue using Mouse Anti-Human MMP-3 Monoclonal Antibody. 500 μg Log in to see 8 to 9 Days
$346.50
Details
Human Mouse Un-conjugated FACS, ELISA, WB Figure 1: Red: Control Antigen (100 ng), Purple: Antigen (10ng), Green: Antigen (50 ng), Blue: Antigen (100 ng) Figure 2: Flow cytometric analysis of NIH/3T3 cells using MMP3 mouse mAb (green) and negative control (red) . 0.1 mg Log in to see 3 to 4 Days
$430.10
Details
Human Rabbit Un-conjugated IF (p), IHC (p), WB Formalin-fixed and paraffin embedded human gastric mucosa labeled with Anti-MMP-3 Polyclonal Antibody (ABIN668301), Unconjugated at 1:200, followed by conjugation to the secondary antibody and DAB staining Lane 1: mouse spleen lysates Lane 2: mouse liver lysates probed with Anti MMP-3 Polyclonal Antibody, Unconjugated (ABIN668301) at 1:200 in 4 °C. Followed by conjugation to secondary antibody at 1:3000 90min in 37 °C. Predicted band 42kD,52kDkD. Observed band size: 52kD. 100 μL Log in to see 3 to 7 Days
$307.45
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB 0.1 mg Log in to see 6 to 8 Days
$390.50
Details

MMP3 Antibodies by Reactivity, Application, Clonality and Conjugate

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Top referenced anti-Matrix Metallopeptidase 3 (Stromelysin 1, Progelatinase) Antibodies

  1. Human Polyclonal MMP3 Primary Antibody for IF (p), IHC (p) - ABIN668301 : Luo, Zhang, Wang, Hu, Song, Su, Zhang: Alendronate retards the progression of lumbar intervertebral disc degeneration in ovariectomized rats. in Bone 2013 (PubMed)
    Show all 7 references for ABIN668301

  2. Human Monoclonal MMP3 Primary Antibody for FACS, ICC - ABIN4899353 : Villeneuve, Block, Le Bousse-Kerdilès, Lepreux, Nurden, Ripoche, Nurden: Tissue inhibitors of matrix metalloproteinases in platelets and megakaryocytes: a novel organization for these secreted proteins. in Experimental hematology 2009 (PubMed)
    Show all 3 references for ABIN4899353

  3. Human Monoclonal MMP3 Primary Antibody for EIA, IHC (p) - ABIN264506 : Saus, Quinones, Otani, Nagase, Harris, Kurkinen: The complete primary structure of human matrix metalloproteinase-3. Identity with stromelysin. in The Journal of biological chemistry 1988 (PubMed)
    Show all 2 references for ABIN264506

  4. Human Polyclonal MMP3 Primary Antibody for EIA, IHC (p) - ABIN358700 : Sage, Reed, Funk, Truong, Steadele, Puolakkainen, Maurice, Bassuk: Cleavage of the matricellular protein SPARC by matrix metalloproteinase 3 produces polypeptides that influence angiogenesis. in The Journal of biological chemistry 2003 (PubMed)
    Show all 2 references for ABIN358700

  5. Human Monoclonal MMP3 Primary Antibody for FACS, ELISA - ABIN969539 : Nan, Niu, Hunter, Han: Missense polymorphisms in matrix metalloproteinase genes and skin cancer risk. in Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2008 (PubMed)
    Show all 2 references for ABIN969539

  6. Human Polyclonal MMP3 Primary Antibody for IF, IHC (p) - ABIN657459 : Zhao, Li, Liao, Luo, Shi, Feng, Chen: Evodiamine Induces Apoptosis and Inhibits Migration of HCT-116 Human Colorectal Cancer Cells. in International journal of molecular sciences 2015 (PubMed)

  7. Dog (Canine) Polyclonal MMP3 Primary Antibody for IHC, WB - ABIN2777122 : Stickel, Osterreicher, Halangk, Berg, Homann, Hellerbrand, Patsenker, Schneider, Kolb, Friess, Schuppan, Puhl, Seitz, Leathart, Day: No role of matrixmetalloproteinase-3 genetic promoter polymorphism 1171 as a risk factor for cirrhosis in alcoholic liver disease. in Alcoholism, clinical and experimental research 2008 (PubMed)

  8. Horse (Equine) Polyclonal MMP3 Primary Antibody for WB - ABIN223232 : De Vries, Dover, Casey, Vandehaar, Plaut: Characterization of mammary stromal remodeling during the dry period. in Journal of dairy science 2010 (PubMed)

More Antibodies against Matrix Metallopeptidase 3 (Stromelysin 1, Progelatinase) Interaction Partners

Mouse (Murine) Matrix Metallopeptidase 3 (Stromelysin 1, Progelatinase) (MMP3) interaction partners

  1. Overexpression of Mmp3 in 3T3-L1 preadipocytes inhibited differentiation. High fat diet-induced obesity downregulates adipocyte MMP3 expression to trigger adipogenesis, and adipocyte TIMP4 (show TIMP4 Antibodies) may modulate this process to regulate hyperplastic vs. hypertrophic adipose tissue expansion, fat distribution, and metabolic health in a sex- and depot-dependent manner.

  2. Matrix metalloprotease (show ADAMTS7 Antibodies) 3 (MMP3), an endogenous neuronal activator of microglia, increased cytokine release from YAC128 microglia compared to wildtype microglia. We found elevated MMP levels in Huntington's Disease (HD) CSF (show CSF2 Antibodies), and MMP levels correlate with disease severity in HD. These data support a novel role for MMPs and microglial activation in HD pathogenesis.

  3. These results indicate that periodic induction, via use of an eye drop, of AAV-mediated secretion of MMP-3 into aqueous humour could have therapeutic potential for those cases of glaucoma that are sub-optimally responsive to conventional pressure-reducing medications.

  4. Data show that loss of loss of matrix metalloproteinase-3 (MMP-3) repressed the upregulation of the chemokines monocyte chemoattractant protein (MCP)-1 (show CPT1B Antibodies) and (C-X-C motif) ligand 1 (CXCL1 (show CXCL1 Antibodies)).

  5. Mmp3-knockout mice maintained higher arterial oxygenation compared to wild-type mice in a model of acute lung injury.

  6. NMP4 (show ZNF384 Antibodies) deficiency suppressed the arthritis-induced increase in bone resorption, expression of RANKL (show TNFSF11 Antibodies) and MMP-3 mRNA.

  7. MMP-3 produced in blood vessel endothelial cells after spinal cord injury serves as an endogenous molecule for microglial activation followed by p38MAPK (show MAPK14 Antibodies) activation and proNGF production

  8. genetic inactivation of MMP-3 has profound effects on the structural integrity and plasticity response of the visual cortex of adult mice

  9. study found significant increases of MMP-3 and MMP-12 (show MMP12 Antibodies) mRNA levels and MMP12 (show MMP12 Antibodies) zymographic activities in response to Cryptococcus neoformans infection but not C. gattii infection

  10. This study demonstrates the sequential involvement of Wnt5, MMP-3, DMP-1 expression, and DMP-1 degradation products by MMP-3, in effecting IL-1beta-induced proliferation of ESC-derived odontoblast-like cells.

Human Matrix Metallopeptidase 3 (Stromelysin 1, Progelatinase) (MMP3) interaction partners

  1. Three previously investigated MMP3 variants (rs679620, rs591058 and rs650108) in addition to the functional promoter variant (rs3025058) were genotyped in 195 Australian control participants and 79 Australian individuals with chronic Achilles tendinopathy.

  2. MMP-3 expression is deregulated in osteosarcomas and this potentially contributes to metastasis and might be a promising marker for the prognosis and therapy of metastatic osteosarcoma.

  3. These results indicate that periodic induction, via use of an eye drop, of AAV-mediated secretion of MMP-3 into aqueous humour could have therapeutic potential for those cases of glaucoma that are sub-optimally responsive to conventional pressure-reducing medications.

  4. the overexpression of HMGB1 (show HMGB1 Antibodies) A-box significantly decreased the IL-1beta (show IL1B Antibodies)-stimulated the production of MMP-1 (show MMP1 Antibodies), MMP-3 and MMP-9 (show MMP9 Antibodies), and also reduced the elevated levels of inducible nitric oxide synthase (iNOS (show NOS2 Antibodies)) and cyclooxygenase-2 (COX-2 (show PTGS2 Antibodies)) associated with the inhibition of prostaglandin E2 (PGE2) and nitric oxide (NO) production in IL-1beta (show IL1B Antibodies)-stimulated chondrocytes.

  5. In summary, our study demonstrates that IL-7 (show IL7 Antibodies)/IL-7R axis promotes the invasion and migration of prostate cancer cells, through activation of AKT (show AKT1 Antibodies)/NF-kappaB (show NFKB1 Antibodies) pathway and upregulation of MMP-3 and MMP-7 (show MMP7 Antibodies) expression

  6. Study showed that serum MMP-3 levels are decreased in patients with epilepsy, which is relevant for acute stroke. A specific pathogenic effect of MMP-3 in epilepsy appears unlikely. This study has demonstrated that the newly developed Luminex assays are useful in quantifying MMP-3 levels in human serum.

  7. Serum baseline levels of MMP-3 are strong prognostic markers of disease activity, and act well as an early predictor of progressive joint damage in recent-onset rheumatoid arthritis.

  8. Up-regulation of MMP-1 (show MMP1 Antibodies)/MMP-3 by IL-1beta (show IL1B Antibodies) and/or TNF-alpha (show TNF Antibodies) in a fraction of chondrocytes in vitro suggests that a subpopulation of catabolic cells may also exist in osteoarthritis.

  9. Study investigated the association between MMP-1 (show MMP1 Antibodies) -1607 1G/2G and MMP-3 -1171 5A/6A genetic polymorphisms and etiological subtypes of ischemic stroke (IS) in the Han Chinese population; MMP-1 (show MMP1 Antibodies) 2G allele was associated with IS due to SAO, whereas patients with IS due to LAA were more likely carriers of the 5A variant in MMP-3

  10. MMP-3 positivity has a strong relationship with meningiomas having an aggressive character; MMP-3 may be used as a proliferation marker for biological behaviour, recurrence rate and prognosis of meningiomas

Pig (Porcine) Matrix Metallopeptidase 3 (Stromelysin 1, Progelatinase) (MMP3) interaction partners

  1. The present study was aimed to determine the association between metalloproteinase 3 (MMP3), transforming growth factor beta 1 (TGFbeta1 (show TGFB1 Antibodies)) and collagen type X alpha I (COL10A1 (show COL10A1 Antibodies)) gene polymorphisms with traits related to leg weakness in pigs.

  2. the identification of MMP1 (show MMP1 Antibodies) and MMP10 (show MMP10 Antibodies) genes in swine is reported.

  3. contribution of MMPs to the inflammatory breakdown of the blood-CSF (show CSF2 Antibodies) barrier in vitro

  4. Results indicate that leukemia inhibitory factor (LIF (show LIF Antibodies)) and Oncostatin M (show OSM Antibodies) increase the expression of MMP-1 (show MMP1 Antibodies), MMP-3, and TIMP-1 (show TIMP1 Antibodies) several fold, and that their expression is reduced to basal levels in the presence of the LIF (show LIF Antibodies) antagonist MH35-BD.

Rabbit Matrix Metallopeptidase 3 (Stromelysin 1, Progelatinase) (MMP3) interaction partners

  1. Compromised autophagy may be related to the osteoarthritis progression; JNK (show MAPK8 Antibodies) and p38 (show MAPK14 Antibodies) MAPKs up-regulate MMP3 and down-regulate autophagy.

  2. chitosan-pDNA nanoparticles encoding shRNA targeting MMP-3 and -13 had great potential in silencing the dedifferentiation-related genes for regenerating prolonged and endurable cartilage.

  3. Ulinastatin (show AMBP Antibodies) effectively inhibited the increased expression of MMP-2 (show MMP2 Antibodies), MMP-3, and iNOS (show NOS2 Antibodies) in degenerated NP cells induced by IL-1beta (show IL1B Antibodies) in vitro.

  4. Tongxinluo can inhibit the expression of MMP-3 and 9 and increase the expression of PPARgamma (show PPARG Antibodies) in atherosclerotic rabbits.

Matrix Metallopeptidase 3 (Stromelysin 1, Progelatinase) (MMP3) Antigen Profile

Protein Summary

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This gene encodes an enzyme which degrades fibronectin, laminin, collagens III, IV, IX, and X, and cartilage proteoglycans. The enzyme is thought to be involved in wound repair, progression of atherosclerosis, and tumor initiation. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3.

Gene names and symbols associated with MMP3

  • matrix metallopeptidase 3 (Mmp3) antibody
  • matrix metallopeptidase 3 (stromelysin 1, progelatinase) (MMP3) antibody
  • matrix metallopeptidase 3 (stromelysin 1, progelatinase) (Mmp3) antibody
  • matrix metallopeptidase 10 (stromelysin 2) (MMP10) antibody
  • CHDS6 antibody
  • MMP-3 antibody
  • MMP3 antibody
  • MMP10 antibody
  • SL-1 antibody
  • SLN-1 antibody
  • SLN1 antibody
  • STMY antibody
  • STMY1 antibody
  • STR-1 antibody
  • STR1 antibody

Protein level used designations for MMP3

EMS-2 , MMP-3 , SL-1 , matrix metalloproteinase 3 , matrix metalloproteinase-3 , progelatinase , stromelysin 1 , stromelysin-1 , transin-1 , PTR1 protein , matrix metalloproteinase 3 (stromelysin 1, progelatinase) , proteoglycanase , stromelysin , metalloproteinase 3 receptor , matrix metallopeptidase 3 (stromelysin 1, progelatinase) , matrix metalloproteinase 10 (stromelysin 2)

GENE ID SPECIES
17392 Mus musculus
171045 Rattus norvegicus
4314 Homo sapiens
396769 Sus scrofa
100009111 Oryctolagus cuniculus
281309 Bos taurus
403445 Canis lupus familiaris
100034195 Equus caballus
100729101 Cavia porcellus
101118895 Ovis aries
418981 Gallus gallus
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