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anti-Mediator Complex Subunit 23 (MED23) Antibodies

The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. Additionally we are shipping MED23 Kits (19) and MED23 Proteins (4) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
MED23 9439 Q9ULK4
MED23 70208 Q80YQ2
MED23 309565  
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Top anti-MED23 Antibodies at antibodies-online.com

Showing 10 out of 47 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-MED23 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:... 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated IF, IHC, ELISA Immunohistochemistry analysis of paraffin-embedded human colon carcino... Immunofluorescence analysis of A549 cells, using MED23 Antibody. The p... 100 μg Log in to see 2 to 3 Days
$275.00
Details
Human Mouse Un-conjugated WB Western blot analysis of Sur-2. HeLa nuclear extracts were probed with... 0.1 mg Log in to see 5 to 6 Days
$236.41
Details
Human Rabbit Un-conjugated IF, ELISA, IHC (p) 100 μL Log in to see 8 to 10 Days
$478.50
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Rabbit Un-conjugated IF, IHC, ELISA 100 μg Log in to see 11 to 16 Days
$412.86
Details
Human Rabbit Un-conjugated ELISA, IF, IHC, WB 100 μL Log in to see 14 Days
$201.19
Details
Human Mouse Un-conjugated ELISA Detection limit for recombinant GST tagged MED23 is 0.03 ng/ml as a ca... 100 μg Log in to see 9 Days
$430.00
Details
Human Rabbit Un-conjugated IP, IHC, ELISA, WB   0.05 mL Log in to see 2 to 3 Days
$481.25
Details
Mouse Rabbit Un-conjugated IHC (p), IP, ELISA, WB 50 μL Log in to see 11 to 13 Days
$541.80
Details

MED23 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
Human , , , ,
,
Mouse (Murine) , , , ,

Rat (Rattus) , , , ,

Top referenced anti-MED23 Antibodies

  1. Human Monoclonal MED23 Primary Antibody for WB - ABIN967286 : Blobel: CREB-binding protein and p300: molecular integrators of hematopoietic transcription. in Blood 2000 (PubMed)
    Show all 3 references for ABIN967286

  2. Human Polyclonal MED23 Primary Antibody for IF, IHC - ABIN1534191 : Mungall, Palmer, Sims, Edwards, Ashurst, Wilming, Jones, Horton, Hunt, Scott, Gilbert, Clamp, Bethel, Milne, Ainscough, Almeida, Ambrose, Andrews, Ashwell, Babbage, Bagguley, Bailey, Banerjee, Barker et al.: The DNA sequence and analysis of human chromosome 6. ... in Nature 2003 (PubMed)
    Show all 2 references for ABIN1534191

  3. Cow (Bovine) Polyclonal MED23 Primary Antibody for WB - ABIN2776066 : Kob, Baniahmad, Escher, von Eggeling, Melle: Detection and identification of transcription factors as interaction partners of alien in vivo. in Cell cycle (Georgetown, Tex.) 2007 (PubMed)

More Antibodies against MED23 Interaction Partners

Human Mediator Complex Subunit 23 (MED23) interaction partners

  1. MED23-associated intellectual disability has been found in two brothers from a non-consanguineous family.

  2. MED23 plays an important role in hepatocarcinogenesis, and it may be a novel target for HCC (show FAM126A Antibodies) therapy.

  3. Upregulation of mediator MED23 in non-small-cell lung cancer promotes the growth, migration, and metastasis of cancer cells.

  4. Mediator MED23 regulates basal transcription in vivo via an interaction with P-TEFb (show CCNT1 Antibodies).

  5. Data show that Med23 RNAi specifically inhibits the proliferation and tumorigenicity of lung cancer cells with hyperactive Ras activity.

  6. missense mutation (p. R617Q) in MED23 that cosegregates with nonsyndromic autosomal recessive intellectual disability; mutation impaired response of JUN and FOS to mitogens by altering interaction between enhancer-bound transcription factors and Mediator

  7. DRIP130 regulates HER2 (show ERBB2 Antibodies) expression by binding to ESX (show ELF3 Antibodies)

  8. loss of DRIP-130 expression, as a result of the gross loss of human chromosome 6q16.3-q23, provokes increased tumor metastasis

  9. Sur2(CRSP3) is required for activation by Adenovirus E1A (show BCKDHA Antibodies) CR3 (show ITGAM Antibodies) activation domain and is required for MAPK (show MAPK1 Antibodies)-mediated activation of Elk-1 (show ELK1 Antibodies).

Mouse (Murine) Mediator Complex Subunit 23 (MED23) interaction partners

  1. MED23 constitutes a molecular node in the regulatory network of anabolic bone formation and related diseases.

  2. Med23 contributes to controlling T-cell activation at the transcriptional level and prevents the development of autoimmunity.

  3. The hepatic Med23 deletion impaired the Mediator and RNAPII recruitment and attenuated the expression of FOXO1 (show FOXO1 Antibodies) target genes.

  4. Data show that Kruppel-like transcription factors KLF2 (show KLF2 Antibodies) expression is decreased in mediator complex Med23 null thymocytes.

  5. Mediator Med23 deficiency enhances neural differentiation of murine embryonic stem cells through modulating BMP signaling.

  6. Reduced expression of MED23 inhibits cell apoptosis by downregulation of Bax (show BAX Antibodies), activated Caspase 3 (show CASP3 Antibodies), activated Caspase 9 (show CASP9 Antibodies) and upregulation of cyclinD1 and Bcl2 (show BCL2 Antibodies).

  7. Data show tha tMed23 deficiency in fibroblasts selectively inhibited the oncogenic transformation induced by Ras.

  8. Mediator MED23 controls the cell fate preference that directs differentiation into smooth muscle cells (SMCs) or adipocytes

  9. MED23 regulates a subset of hnRNP L (show HNRNPL Antibodies)-targeted alternative splicing (AS) and alternative cleavage and polyadenylation (APA (show ENPEP Antibodies)) events.

  10. MED23 Mediator controls Egr1 gene and stimulates Pol II initiation at a step subsequent to preinitiation complex assembly

MED23 Antigen Profile

Protein Summary

The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors. This protein also acts as a metastasis suppressor. Several alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Gene names and symbols associated with MED23

  • Mediator complex subunit 23 (MED23) antibody
  • mediator complex subunit 23 (MED23) antibody
  • mediator complex subunit 23 (LOC100342894) antibody
  • mediator complex subunit 23 (med23) antibody
  • mediator of RNA polymerase II transcription subunit 23 (MED23) antibody
  • mediator complex subunit 23 (Med23) antibody
  • Protein SUR-2 (sur-2) antibody
  • 130kDa antibody
  • 3000002A17Rik antibody
  • ARC130 antibody
  • CG3695 antibody
  • crsp3 antibody
  • CRSP130 antibody
  • CRSP133 antibody
  • Dmel\\CG3695 antibody
  • DRIP130 antibody
  • dSUR2 antibody
  • dTRAP150beta antibody
  • ESTM7 antibody
  • Gal11/SUR2 antibody
  • MED23 antibody
  • mKIAA1216 antibody
  • MRT18 antibody
  • si:ch211-272f15.2 antibody
  • SUR-2 antibody
  • Sur2 antibody
  • Trap150 antibody
  • Trap150beta antibody
  • X83317 antibody
  • zgc:91979 antibody

Protein level used designations for MED23

CG3695-PA , CG3695-PB , MED23-PA , MED23-PB , mediator complex subunit 23 , mediator complex subunit n23 , cofactor required for Sp1 transcriptional activation, subunit 3, 130kDa , Sp1 transcriptional activation cofactor subunit 3 , mediator of RNA polymerase II transcription subunit 23-like , mediator of RNA polymerase II transcription subunit 23 , 130 kDa transcriptional co-activator , 133 kDa transcriptional co-activator , activator-recruited cofactor 130 kDa component , cofactor required for Sp1 transcriptional activation subunit 3 , vitamin D3 receptor interacting protein , CRSP complex subunit 3 , cofactor required for Sp1 transcriptional activation, subunit 3 (130kD) , mSur-2 , protein sur-2 homolog , cofactor required for Sp1 transcriptional activation, subunit 3

GENE ID SPECIES
37639 Drosophila melanogaster
426927 Gallus gallus
472124 Pan troglodytes
474822 Canis lupus familiaris
100067556 Equus caballus
100342894 Oryctolagus cuniculus
100409950 Callithrix jacchus
100433008 Pongo abelii
100545205 Meleagris gallopavo
100562268 Anolis carolinensis
100602785 Nomascus leucogenys
412332 Apis mellifera
100466100 Ailuropoda melanoleuca
9439 Homo sapiens
70208 Mus musculus
309565 Rattus norvegicus
445483 Danio rerio
399060 Xenopus laevis
513610 Bos taurus
173345 Caenorhabditis elegans
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