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May control cell migration by relaying extracellular chemotactic signals to the microtubule cytoskeleton. Additionally we are shipping MEMO1 Antibodies (39) and MEMO1 Proteins (10) and many more products for this protein.
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Biochemical assays revealed that Memo is a copper-dependent redox enzyme that promoted a more oxidized intracellular milieu and stimulated the production of reactive oxygen species (ROS (show ROS1 ELISA Kits)) in cellular structures involved in migration.
Mediator of ERBB2 (show ERBB2 ELISA Kits)-driven cell motility (MEMO) promotes extranuclear estrogen receptor (show ESR1 ELISA Kits) signaling involving the growth factor receptors IGF1R (show IGF1R ELISA Kits) and ERBB2 (show ERBB2 ELISA Kits).
MEMO1 is involved in breast carcinogenesis via regulating insulin-like growth factor-I receptor (show IGF1R ELISA Kits)-dependent signaling events.
data suggest that Memo controls cell migration by relaying extracellular chemotactic signals to the microtubule cytoskeleton [Memo]
Memo-RhoA-mDia1 signaling coordinates the organization of the lamellipodial actin network, adhesion site formation, and microtubule outgrowth within the cell leading edge to sustain cell motility.
Memo was detected in complexes with cofilin (show CFL1 ELISA Kits), ErbB2 (show ERBB2 ELISA Kits) and PLCgamma1 (show PLCG1 ELISA Kits).
our results show that Memo has a novel role in the S1P (show S1PR1 ELISA Kits) pathway and that Memo is needed to promote cell-autonomous S1PR activation.
tissue distribution of Memo in mice.
May control cell migration by relaying extracellular chemotactic signals to the microtubule cytoskeleton. Mediator of ERBB2 signaling. The MEMO1-RHOA-DIAPH1 signaling pathway plays an important role in ERBB2-dependent stabilization of microtubules at the cell cortex. It controls the localization of APC and CLASP2 to the cell membrane, via the regulation of GSK3B activity. In turn, membrane-bound APC allows the localization of the MACF1 to the cell membrane, which is required for microtubule capture and stabilization (By similarity).
, C21orf19-like protein
, protein memo
, mediator of ErbB2-driven cell motility 1
, mediator of cell motility 1
, Methylation modifier for class I HLA
, HCV NS5A-transactivated protein 7
, hepatitis C virus NS5A-transactivated protein 7