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anti-Megakaryocyte-Associated tyrosine Kinase (MATK) Antibodies

The protein encoded by MATK has amino acid sequence similarity to Csk tyrosine kinase and has the structural features of the CSK subfamily: SRC homology SH2 and SH3 domains, a catalytic domain, a unique N terminus, lack of myristylation signals, lack. Additionally we are shipping Megakaryocyte-Associated tyrosine Kinase Proteins (8) and Megakaryocyte-Associated tyrosine Kinase Kits (3) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
MATK 4145 P42679
MATK 17179 P41242
MATK 60450 P41243
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Top anti-Megakaryocyte-Associated tyrosine Kinase Antibodies at antibodies-online.com

Showing 10 out of 105 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated EIA, IHC (p), WB 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated WB MATK Antibody (M1) (ABIN392103) western blot analysis in HL-60 cell line lysates (35 µg/lane).This demonstrates the MATK antibody detected the MATK protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Mouse Un-conjugated FACS, ELISA, WB Figure 1: Flow cytometric analysis of K562 cells using MATK mouse mAb (green) and negative control (purple) . Figure 2: Western blot analysis using MATK mouse mAb against K562 cell lysate (1) . 100 μL Log in to see 3 to 4 Days
$393.80
Details
Mouse Rabbit Un-conjugated IHC (p), WB Mouse Matk Antibody (C-term) (ABIN658192) western blot analysis in mouse spleen tissue lysates (35 µg/lane). This demonstrates the Matk antibody detected the Matk protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated WB The anti-CHK Pab (ABIN391080) is used in Western blot to detect CHK in mouse heart tissue lysate. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated WB 100 μL Log in to see 8 to 10 Days
$507.83
Details
Human Mouse Un-conjugated FACS, WB   100 μL Log in to see 10 to 11 Days
$550.00
Details
Human Mouse Un-conjugated ICC, FACS, ELISA, WB 100 μL Log in to see 8 to 10 Days
$522.50
Details
Human Mouse Un-conjugated EIA, WB 0.1 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Alkaline Phosphatase (AP) IHC, ELISA, WB   200 μL Log in to see 8 to 10 Days
$969.83
Details

MATK Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-Megakaryocyte-Associated tyrosine Kinase Antibodies

  1. Human Polyclonal MATK Primary Antibody for EIA, IHC (p) - ABIN359988 : Kim, Zagozdzon, Meisler, Baleja, Fu, Avraham, Avraham: Csk homologous kinase (CHK) and ErbB-2 interactions are directly coupled with CHK negative growth regulatory function in breast cancer. in The Journal of biological chemistry 2002 (PubMed)
    Show all 5 references for ABIN359988

  2. Human Polyclonal MATK Primary Antibody for WB - ABIN392103 : Zagozdzon, Bougeret, Fu, Avraham: Overexpression of the Csk homologous kinase facilitates phosphorylation of Akt/PKB in MCF-7 cells. in International journal of oncology 2002 (PubMed)
    Show all 4 references for ABIN392103

  3. Human Monoclonal MATK Primary Antibody for FACS, WB - ABIN2869448 : McShan, Zagozdzon, Park, Zrihan-Licht, Fu, Avraham, Avraham: Csk homologous kinase associates with RAFTK/Pyk2 in breast cancer cells and negatively regulates its activation and breast cancer cell migration. in International journal of oncology 2002 (PubMed)
    Show all 3 references for ABIN2869448

  4. Human Monoclonal MATK Primary Antibody for FACS, ELISA - ABIN969495 : Strausberg, Feingold, Grouse, Derge, Klausner, Collins, Wagner, Shenmen, Schuler, Altschul, Zeeberg, Buetow, Schaefer, Bhat, Hopkins, Jordan, Moore, Max, Wang, Hsieh, Diatchenko, Marusina, Farmer et al.: Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. ... in Proceedings of the National Academy of Sciences of the United States of America 2002 (PubMed)
    Show all 3 references for ABIN969495

More Antibodies against Megakaryocyte-Associated tyrosine Kinase Interaction Partners

Human Megakaryocyte-Associated tyrosine Kinase (MATK) interaction partners

  1. After IGF-I (show IGF1 Antibodies) stimulation, CTK is recruited to IGF-IR and its recruitment facilitates CTK's subsequent association with phospho-SHPS-1 (show SIRPA Antibodies).

  2. ERBB2 binds to the SH2 domain of CHK and inhibits cell growth in human breast tumor cell lines

  3. Overexpression of the Csk homologous kinase facilitates phosphorylation of akt/protein kinase b (show AKT1 Antibodies) in breast neoplasms

  4. CHK (show CHKA Antibodies) Leu223 stabilizes the movement of the alphaC-helix of the protein tyrosine kinase (show EPHA8 Antibodies)

  5. Loss of CHK expression is associated with human brain tumors

  6. Nuclear multi-lobulation in late S phase, which is dependent on polymerization and depolymerization of microtubules, may be involved in nuclear Chk-induced inhibition of proliferation.

  7. striking functional differences between the Csk and Chk SH2 domains and revealed functional similarities between the Chk and Src SH2 domains

  8. This study describes for the first time the Src-independent actions of CHK and provides novel insights into CHK function in neural cells.

  9. Matk/CHK is not functionally redundant with Csk (show CSK Antibodies), and this tyrosine kinase (show TXK Antibodies) plays an important role as a regulator of immunologic responses

  10. Findings indicate that the importance of the N-terminal domain to Chk-induced tyrosine phosphorylation in the nucleus, and implicate that nuclear tyrosine-phosphorylated proteins may contribute to inhibition of cell proliferation.

Cow (Bovine) Megakaryocyte-Associated tyrosine Kinase (MATK) interaction partners

  1. After IGF-I (show IGF1 Antibodies) stimulation, CTK is recruited to IGF-IR and its recruitment facilitates CTK's subsequent association with phospho-SHPS-1 (show SIRPA Antibodies).

Megakaryocyte-Associated tyrosine Kinase (MATK) Antigen Profile

Protein Summary

The protein encoded by this gene has amino acid sequence similarity to Csk tyrosine kinase and has the structural features of the CSK subfamily: SRC homology SH2 and SH3 domains, a catalytic domain, a unique N terminus, lack of myristylation signals, lack of a negative regulatory phosphorylation site, and lack of an autophosphorylation site. This protein is thought to play a significant role in the signal transduction of hematopoietic cells. It is able to phosphorylate and inactivate Src family kinases, and may play an inhibitory role in the control of T-cell proliferation. This protein might be involved in signaling in some cases of breast cancer. Three alternatively spliced transcript variants that encode different isoforms have been described for this gene.

Gene names and symbols associated with MATK

  • megakaryocyte-associated tyrosine kinase (matk) antibody
  • megakaryocyte-associated tyrosine kinase (MATK) antibody
  • megakaryocyte-associated tyrosine kinase (Matk) antibody
  • Batk antibody
  • CHK antibody
  • CTK antibody
  • HHYLTK antibody
  • HYL antibody
  • HYLTK antibody
  • Lsk antibody
  • Ntk antibody
  • si:ch211-63j24.2 antibody

Protein level used designations for MATK

megakaryocyte-associated tyrosine kinase , megakaryocyte-associated tyrosine-protein kinase-like , CSK homologous kinase , Csk-homologous kinase , Csk-type protein tyrosine kinase , HYL tyrosine kinase , hematopoietic consensus tyrosine-lacking kinase , hydroxyaryl-protein kinase , leukocyte carboxyl-terminal src kinase related , megakaryocyte-associated tyrosine-protein kinase , protein kinase HYL , tyrosine kinase MATK , tyrosine-protein kinase CTK , tyrosylprotein kinase , Csk homologous kinase , protein kinase NTK , megakaryocyte-associated tyrosine kinase (non-receptor protein tyrosine kinase) , non-receptor protein kinase protein , protein kinase BATK , carboxyl-terminal SRC kinase homologous kinase

GENE ID SPECIES
567405 Danio rerio
769076 Gallus gallus
100477232 Ailuropoda melanoleuca
4145 Homo sapiens
17179 Mus musculus
60450 Rattus norvegicus
611999 Canis lupus familiaris
100521543 Sus scrofa
504668 Bos taurus
Selected quality suppliers for anti-Megakaryocyte-Associated tyrosine Kinase (MATK) Antibodies
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