Meis Homeobox 2 Proteins (MEIS2)

MEIS2 encodes a homeobox protein belonging to the TALE ('three amino acid loop extension') family of homeodomain-containing proteins. Additionally we are shipping MEIS2 Antibodies (92) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
MEIS2 4212 O14770
MEIS2 17536 P97367
Rat MEIS2 MEIS2 311311  
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Top MEIS2 Proteins at

Showing 4 out of 6 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 60 Days
Insect Cells Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 60 Days
HOST_HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Log in to see 10 to 12 Days
HOST_Wheat germ Human GST tag 10 μg Log in to see 11 to 12 Days

MEIS2 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
, ,
Mouse (Murine)

More Proteins for Meis Homeobox 2 (MEIS2) Interaction Partners

Human Meis Homeobox 2 (MEIS2) interaction partners

  1. we have identified a novel nonsense MEIS2 mutation in a female patient with cleft palate, cardiac septal defect, severe ID, developmental delay and feeding difficulty with gastro-esophageal reflux. Our findings strongly suggest neurocristopathy be included in the clinical features associated with MEIS2 alterations.

  2. Meis2 as the target of miR (show MLXIP Proteins)-134 in the regulation of cardiomyocyte progenitor cell proliferation.

  3. This is the first report showing a de novo small intragenic mutation in MEIS2 and further confirms the important role of this gene in normal development.

  4. Our results show that MEIS2 is a gene needed for palate closure. In syndromic cases of cleft palate, MEIS2 should be considered among the candidate genes, for example, in cases without 22q11.2 deletions.

  5. FOXM1 (show FOXM1 Proteins) is a direct target gene of MEIS2 and is required for MEIS2 to upregulate mitotic genes.

  6. The data suggest existence of a complex regulatory pathway in the trabecular meshwork part of which includes interactions between FOXC1 (show FOXC1 Proteins), miR (show MLXIP Proteins)-204, MEIS2, and ITGbeta1.

  7. Klf4 (show KLF4 Proteins) recruits a complex of Meis and Pbx proteins to DNA, resulting in Meis2 transcriptional activation domain-dependent activation of a subset of Klf4 (show KLF4 Proteins) target genes.

  8. The Single Nucleotide Polymorphism in Meis homeobox 2 (MEIS2) mediated the effects of risperidone on hip circumference (q=0.004).

  9. Transgenic mice lacking microRNAs miR (show MLXIP Proteins)-9-2 and miR (show MLXIP Proteins)-9-3 exhibit multiple defects of telencephalic structures which may be brought about by dysregulation of Foxg1 (show FOXG1 Proteins), Nr2e1 (show NR2E1 Proteins), Gsh2 (show GSX2 Proteins), and Meis2 expression.

  10. Data demonstrate by in situ hybridization and immunohistochemistry that the two homeobox (show Lbx1 Proteins) genes Pax6 (show PAX6 Proteins) and MEIS2 are expressed during early fetal brain development in humans.

Mouse (Murine) Meis Homeobox 2 (MEIS2) interaction partners

  1. Hoxa2, Meis and Pbx proteins act cooperatively on the ECR, via a core 32 bp sequence, to regulate Hmx1 expression.

  2. We found that expression of Emx2 (show EMX2 Proteins) and Lhx2 (show LHX2 Proteins) initiated between neuronal progenitor and neuronal precursor stages. As far as the sensory neurons of the vomeronasal organ are concerned, Meis1 (show MEIS1 Proteins) and Meis2 were only expressed in the apical layer, together with Gnai2 (show GNAI2 Proteins), but not in the basal layer.

  3. we show that simultaneous deletion of Meis1 (show MEIS1 Proteins) and Meis2 in presumptive lens ectoderm results in arrested lens development in the pre-placodal stage, and neither lens placode nor lens is formed. We found that in the presumptive lens ectoderm of Meis1 (show MEIS1 Proteins)/Meis2 deficient embryos Pax6 (show PAX6 Proteins) expression is absent

  4. Meis2-null mice are embryonic lethal. The results reveal a critical role of Meis2 during cranial and cardiac neural crest cells development in mouse.

  5. Data suggest that the RING1 (show RING1 Proteins)-MEIS1 (show MEIS1 Proteins)/2 axis is regulated by early PD signals and contributes to the initiation or maintenance of the distal signal circuitry.

  6. Interaction of Meis2 promoter with midbrain enhancer depends on RING1.

  7. Meis2 cooperates with Pax6 (show PAX6 Proteins) in generic neurogenesis and dopaminergic fate specification in the adult subventricular zone-olfactory bulb system.

  8. These data identify Meis2 as a marker for the study of amacrine cell diversity and development in addition to providing evidence for the stepwise specification of the glycinergic and GABAergic neurotransmitter phenotypes during AM cell differentiation.

  9. Retinal progenitor cells (RPCs) in chicks and mice express two Hth-related proteins, Meis1 (show MEIS1 Proteins) and Meis2.

MEIS2 Protein Profile

Protein Summary

This gene encodes a homeobox protein belonging to the TALE ('three amino acid loop extension') family of homeodomain-containing proteins. TALE homeobox proteins are highly conserved transcription regulators, and several members have been shown to be essential contributors to developmental programs. Multiple transcript variants encoding distinct isoforms have been described for this gene.

Gene names and symbols associated with Meis Homeobox 2 Proteins (MEIS2)

  • Meis homeobox 2 (MEIS2)
  • Meis homeobox 2 (meis2)
  • myeloid ecotropic viral integration site 2a (meis2a)
  • Meis homeobox 2 (Meis2)
  • myeloid ecotropic viral integration site 2b (meis2b)
  • A430109D20Rik protein
  • DKFZp469A1832 protein
  • fa26d08 protein
  • HsT18361 protein
  • meis2 protein
  • meis2.1 protein
  • meis2.2 protein
  • Meis2a.1 protein
  • Meis2a.2 protein
  • Mrg1 protein
  • Stra10 protein
  • wu:fa26d08 protein

Protein level used designations for Meis Homeobox 2 Proteins (MEIS2)

Meis homeobox 2 , homeobox protein Meis2-like , homeobox protein Meis2 , myeloid ecotropic viral integration site 2.2 , XMeis1-3 protein , Meis1, myeloid ecotropic viral integration site 1 homolog 2 , homeoprotein Meis2a.1 , homeoprotein Meis2a.2 , myeloid ecotropic viral insertion site-2a protein , Meis homolog 2 , Meis1-related gene 1 , TALE homeobox protein Meis2 , meis1-related protein 1 , Cbp/p300-interacting transactivator with Glu/Asp-rich carboxy-terminal domain 2 , myeloid ecotropic viral integration site-related gene 1 , myeloid ecotropic viral integration site 2.1

100057556 Equus caballus
453312 Pan troglodytes
699748 Macaca mulatta
100027000 Monodelphis domestica
100036664 Xenopus (Silurana) tropicalis
100174200 Pongo abelii
100392593 Callithrix jacchus
100470022 Ailuropoda melanoleuca
100581076 Nomascus leucogenys
170454 Danio rerio
398167 Xenopus laevis
395588 Gallus gallus
4212 Homo sapiens
612759 Canis lupus familiaris
539573 Bos taurus
17536 Mus musculus
311311 Rattus norvegicus
100512756 Sus scrofa
30066 Danio rerio
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