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Melanin-Concentrating Hormone Receptor 1 Proteins (MCHR1)

The protein encoded by MCHR1, a member of the G protein-coupled receptor family 1, is an integral plasma membrane protein which binds melanin-concentrating hormone. Additionally we are shipping MCHR1 Antibodies (88) and MCHR1 Kits (9) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
MCHR1 2847 Q99705
MCHR1 207911 Q8JZL2
Rat MCHR1 MCHR1 83567 P97639
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Top MCHR1 Proteins at antibodies-online.com

Showing 6 out of 8 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 49 to 54 Days
$4,244.78
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 49 to 54 Days
$6,041.49
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Wheat germ Human Un-conjugated   10 μg Log in to see 9 Days
$641.43
Details

MCHR1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
, ,
Mouse (Murine) ,
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More Proteins for Melanin-Concentrating Hormone Receptor 1 (MCHR1) Interaction Partners

Human Melanin-Concentrating Hormone Receptor 1 (MCHR1) interaction partners

  1. Polymorphisms in the MCHR1 gene are associated with differences in body composition and interact with physiologic and energy-related lifestyle factors.

  2. results suggest that MCHR1 may influence schizophrenia susceptibility, in particular among men and patients responding to conventional (nonclozapine) treatment

  3. SLC-1 protein human mutation demonstrated important genetic susceptibility of sporadic nonsyndromic hearing loss in China.

  4. DNA methylation (show HELLS Proteins) at MCHR1 is allele-specific, age-dependent, body mass index-associated and affects transcription.

  5. two loss-of-function mutants were identified in markedly underweight individuals, raising the possibility that a lean phenotype may be linked to deficient MCHR1 signaling

  6. MCHR1 expression level was 1.6 times higher in vitiligo (show MITF Proteins) uninvolved skin (P < 0.05) and 2.23 times lower in involved skin (P < 0.05), when compared to healthy control skin.

  7. data suggest that RGS2 (show RGS2 Proteins) and RGS8 (show RGS8 Proteins) differentially associate with MCHR1 and may represent two distinct modes of signaling mechanisms in vivo

  8. Synthesis and biological evaluation in vitro of a selective, high potency peptide agonist of human melanin-concentrating hormone (show PMCH Proteins) action at human melanin-concentrating hormone receptor 1.

  9. MCH1 and MCH2 receptors were investigated and are different from those in SVK14 cells.

  10. MCHR1 is expressed and functional in human skin

Mouse (Murine) Melanin-Concentrating Hormone Receptor 1 (MCHR1) interaction partners

  1. The present work is the first study to systematically compare the effects of MCH (show PMCH Proteins) signaling on behavioral and metabolic phenotypes.[Meta-analysis]

  2. This study supports the use of the Mchr1-cre mouse for outlining the neuroanatomical distribution and neurochemical phenotype of MCHR1 neurons.

  3. This study demonistrated that lack of MCH (show PMCH Proteins) receptor provoked a ventricular size increase and beat frequency of ependymal cilia.

  4. Mchr1 and Sstr3 (show SSTR3 Proteins) are expressed and colocalized within cilia in multiple mouse brain regions, and they form heteromers.

  5. Disruption of the melanin-concentrating hormone receptor 1 (MCH1R) affects thyroid function

  6. The elevated basal body temperature and reduction in NREM sleep time resulting from shorter NREM episode durations observed in knockout mice suggests that central MCH (show PMCH Proteins)(1) receptor has a role in thermoregulation and presumably stabilization of NREM sleep.

  7. Data show that the melanin-concentrating hormone (show PMCH Proteins)/MCH1R system is one of the players mediating behavioral and metabolic responses upon increased caloric consumption.

  8. In melanin-concentrating hormone receptor 1 knock-out mice, long-term synaptic depression was strongly diminished in hippocampus.

  9. The data indicate that the MCH (show PMCH Proteins) system is involved in the regulation of PTZ and pilocarpine seizure threshold.

  10. The gene encoding the mouse melanin-concentrating hormone receptor 1 was isolated and its structural organization and flanking regions were characterized.

MCHR1 Protein Profile

Protein Summary

The protein encoded by this gene, a member of the G protein-coupled receptor family 1, is an integral plasma membrane protein which binds melanin-concentrating hormone. The encoded protein can inhibit cAMP accumulation and stimulate intracellular calcium flux, and is probably involved in the neuronal regulation of food consumption. Although structurally similar to somatostatin receptors, this protein does not seem to bind somatostatin.

Gene names and symbols associated with MCHR1

  • melanin-concentrating hormone receptor 1 (MCHR1)
  • melanin-concentrating hormone receptor 1 (Mchr1)
  • AW049955 protein
  • Gpr24 protein
  • Mch-1r protein
  • MCH-R1 protein
  • Mch1r protein
  • MCHR1 protein
  • SLC-1 protein
  • Slc1 protein

Protein level used designations for MCHR1

G protein-coupled receptor 24 , MCH receptor 1 , somatostatin receptor-like protein , G protein coupled receptor 24 , G-protein coupled receptor 24 , Gpr24-9 protein coupled receptor , MCHR , SLC-1 , MCH-R1 , MCH1R , MCHR-1 , MCH-1R , melanin-concentrating hormone receptor subtype 1

GENE ID SPECIES
2847 Homo sapiens
207911 Mus musculus
83567 Rattus norvegicus
397295 Sus scrofa
470220 Pan troglodytes
574232 Macaca mulatta
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