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MC5R encodes a member of the seven-pass transmembrane G protein-coupled melanocortin receptor protein family that stimulate cAMP signal transduction. Additionally we are shipping MC5 Receptor Kits (12) and MC5 Receptor Proteins (3) and many more products for this protein.
Showing 10 out of 91 products:
Human Polyclonal MC5 Receptor Primary Antibody for WB - ABIN375093
Grieco, Cai, Han, Trivedi, Campiglia, Novellino, Hruby: Further structure-activity studies of lactam derivatives of MT-II and SHU-9119: their activity and selectivity at human melanocortin receptors 3, 4, and 5. in Peptides 2007
melanocortin receptors MC2R (show MC2R Antibodies), MC3R (show MC3R Antibodies) and MC5R are most abundantly expressed in glandular epithelium of the endometrium
MC2R (show MC2R Antibodies) and MC1R (show MSHR Antibodies) signals are consecutively required for the regulation of EPO (show EPO Antibodies) signal transduction in erythroblast differentiation, and MC5R signal transduction is required to induce enucleation.
D115 and D119 in TM3 (show TPM1 Antibodies), F195 in TM5, and F254 in TM6 may form a binding pocket for NDP (show NDP Antibodies)-alpha-MSH binding.
Melanocortin 5 receptor signaling and internalization: role of MAPK/ERK (show MAPK1 Antibodies) pathway and beta-arrestins 1/2.
Data suggest that antagonists of MC1R (show MSHR Antibodies) and MC5R could be effective inhibitors of sebaceous gland differentiation and the production of sebum-specific lipids.
Variations in the melanocortin 5 receptor gene are unlikely to confer susceptibility to bipolar disorder in this sample.
Further structure-activity studies of lactam derivatives of MT-II (show MT2 Antibodies) and SHU-9119 were made at MC5R.
MC5R signals through a PI3K (show PIK3CA Antibodies)-regulated Akt (show AKT1 Antibodies)-independent pathway leading to downstream activation of ERK1/2 (show MAPK1/3 Antibodies)
MC5r-dependent regulatory immunity increased CD11b (show ITGAM Antibodies)(+)F4/80(+)Ly-6C(low)Ly-6G(+)CD39 (show ENTPD1 Antibodies)(+)CD73(+) APCs (show APCS Antibodies) in the spleen of post-experimental autoimmune uveoretinitis mice.
In 3T3-L1 adipocytes, alpha-MSH-activated MC5-R signals through the cAMP/PKA and MAPK (show MAPK1 Antibodies)/ERK1/2 (show MAPK1/3 Antibodies) pathways.
Melanocortin receptors 1 and 5 might mediate inhibitory effects of alpha-melanocyte-stimulating hormone on antigen-induced chronic allergic skin inflammation in IgE transgenic mice.
Dependence on MC5r expression promotes or selectively activates IRBP (show RBP3 Antibodies)-specific FoxP3 (show FOXP3 Antibodies)+ TGF-beta (show TGFB1 Antibodies)+ CD25 (show IL2RA Antibodies)+CD4 (show CD4 Antibodies)+ Treg cells in the spleens of experimental uveitis-recovered mice.
melanocortin 2 receptor (show MC2R Antibodies) and melanocortin 5 receptor are lipolytic mediators in differentiated 3T3-L1 adipocytes
Data show that melanocortins regulate Il6 (show IL6 Antibodies) gene expression and production in 3T3-L1 adipocytes through melanocortin receptors 2 and 5.
The results establish that MRAP forms stable complexes with two different melanocortin receptors, facilitating surface expression of MC2 receptor (show MC2R Antibodies) but disrupting dimerization and surface localization of MC5 receptor.
This gene encodes a member of the seven-pass transmembrane G protein-coupled melanocortin receptor protein family that stimulate cAMP signal transduction. The encoded protein is a receptor for melanocyte-stimulating hormone and adrenocorticotropic hormone and is suggested to play a role in sebum generation.
, melanocortin receptor 5
, G-protein-coupled receptor
, melanocortin 5 receptor
, melanocortin 1 receptor Mc1r
, melanocortin-5 receptor