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MAGEA6 is a member of the MAGEA gene family. Additionally we are shipping MAGEA6 Antibodies (40) and and many more products for this protein.
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Human MAGEA6 Protein expressed in Escherichia coli (E. coli) - ABIN1098292
Klein, Bueler, Mulligan: Comparative analysis of genetically modified dendritic cells and tumor cells as therapeutic cancer vaccines. in The Journal of experimental medicine 2000
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MAGEA3 (show MAGEA3 Proteins)/6 positivity was associated with significantly better disease-free survival.
Study describes a widespread mechanism to suppress AMPK (show PRKAA1 Proteins) through its ubiquitination and degradation by the cancer-specific MAGE-A3 (show MAGEA3 Proteins)/6-TRIM28 (show TRIM28 Proteins) ubiquitin ligase. MAGE-A3 (show MAGEA3 Proteins) and MAGE-A6 are highly similar proteins normally expressed only in the male germline but frequently re-activated in human cancers.
To identify novel CTL epitopes from MAGE-A6 and MAGE (show MAGEB10 Proteins)-A12 (show UGT1A9 Proteins) antigens.
Report MAGEA1 (show MAGEA1 Proteins)-A6 expression in sputum suggests presence of lung cancer cells or precancerous cells.
Disease-associated bias in T helper type 1 (Th1 (show TH1L Proteins))/Th2 CD4 (show CD4 Proteins)(+) T cell responses against MAGE-6 in HLA-DRB10401(+) patients with renal cell carcinoma (show MOK Proteins) or melanoma.
MAGE-6 encodes HLA-DRbeta1*0401-presented epitopes recognized by CD4 (show CD4 Proteins)+ T cells from patients with melanoma or renal cell carcinoma (show MOK Proteins)
Multiple simultaneous detection of MAGE (show MAGEB10 Proteins)-A [subtypes] more specific and sensitive than detection of single MAGE (show MAGEB10 Proteins)-A antigen for the diagnostic and prognostic evaluation of oral squamous cell carcinoma
This gene is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80% sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some hereditary disorders, such as dyskeratosis congenita. Two transcript variants encoding the same protein have been identified for this gene.
melanoma antigen family A, 6
, MAGE-6 antigen
, MAGE3B antigen
, cancer/testis antigen 1.6
, cancer/testis antigen family 1, member 6
, melanoma-associated antigen 6