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MAGEC2 is a member of the MAGEC gene family. Additionally we are shipping MAGEC2 Proteins (3) and many more products for this protein.
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our findings revealed a previously unrecognized regulation of STAT3 (show STAT3 Antibodies) activation in tumor cells by cancer/testis antigen MAGEC2, and provided a molecular mechanism for the oncogenic activity of MAGEC2 in cancer cells.
High MAGE-C2 expression was found in 38.18% of triple negative breast cancer tissues and in 9.09% of adjacent tissues. High MAGE-C2 expression in TNBC patients was closely associated with tumor node metastasis and shorter survival time.
our study provides a suitable cell model for exploring the biological functions of MAGEC2 in malignant cells, and sheds light on the molecular pathway by which MAGEC2 promotes tumor development.
The expressions of MAGE-C2 mRNA and MAGE-C2 protein were closely associated with stage, metastasis of lung cancer.
Data show that melanoma antigen, family C, 2 protein (MAGE-C2) binds with RING-box protein 1 (Rbx1) and Cullin 1, and regulates cyclin E stability in melanoma cells.
MAGE-C1 (show MAGEC1 Antibodies) and MAGE-C2 expressions were positively associated with high tumor grade and reduced recurrence-free survival in breast cancer.
expression of CT7 (show MAGEC1 Antibodies) and CT10 throughout the different subtypes of mucosal melanoma and tumor development.
MAGE-C1 (show MAGEC1 Antibodies) and MAGE-C2 are expressed in myeloma, but the chromosome aberrations do not always correlate with expression
In gastrointestinal stromal tumors, 5/51 (10%) patients expressed MAGE-C2. High-grade GIST are more likely to express MAGE-C2. MAGE-C2 also significantly correlates with mitotic rate and tumor size.
Our results indicate that MAGEC2 has a role in breast cancer metastasis through inducing epithelial-mesenchymal transition
This gene is a member of the MAGEC gene family. It is not expressed in normal tissues, except for testis, and is expressed in tumors of various histological types. This gene and the other MAGEC genes are clustered on chromosome Xq26-q27.
melanoma antigen family C, 2
, melanoma antigen family E, 1
, melanoma-associated antigen E1-like
, MAGE-C2 antigen
, MAGE-E1 antigen
, cancer/testis antigen 10
, hepatocellular cancer antigen 587
, hepatocellular carcinoma-associated antigen 587
, melanoma antigen, family E, 1, cancer/testis specific
, melanoma-associated antigen C2