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Melanoma Associated Chondroitin Sulfate Proteoglycan Proteins (MCSP)

A human melanoma-associated chondroitin sulfate proteoglycan plays a role in stabilizing cell-substratum interactions during early events of melanoma cell spreading on endothelial basement membranes. Additionally we are shipping NG2 Antibodies (101) and NG2 Kits (15) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
Mouse MCSP MCSP 121021 Q8VHY0
MCSP 1464 Q6UVK1
MCSP 81651 Q00657
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Top NG2 Proteins at antibodies-online.com

Showing 4 out of 8 products:

Catalog No. Origin Source Conjugate Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag 100 μg Log in to see 11 to 13 Days
$704.00
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HOST_Escherichia coli (E. coli) Rat His tag 100 μg Log in to see 11 to 13 Days
$844.80
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HOST_Escherichia coli (E. coli) Human Un-conjugated 100 μg Log in to see 9 to 19 Days
$889.07
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HOST_Escherichia coli (E. coli) Rat Un-conjugated 100 μg Log in to see 9 to 19 Days
$1,014.95
Details

MCSP Proteins by Origin and Source

Origin Expressed in Conjugate
Human

Rat (Rattus)
,

More Proteins for Melanoma Associated Chondroitin Sulfate Proteoglycan (MCSP) Interaction Partners

Mouse (Murine) Melanoma Associated Chondroitin Sulfate Proteoglycan (MCSP) interaction partners

  1. NG2 (show Vcan Proteins) protein is not required for glutamatergic neuron-NG2 (show Vcan Proteins) cell synaptic signaling

  2. This study demonstrated that NG2 (show Vcan Proteins) is an important factor in OPC-dependent regeneration of white matter following spinal cord demyelination.

  3. NF-kappaB (show NFKB1 Proteins) in NG2 (show Vcan Proteins)(+) cells promotes myoblast migration to the tips of myofibers through cell-cell contact through expression of ephrinA5 from NG2 (show Vcan Proteins)(+) cells

  4. The NG2 (show Vcan Proteins) proteoglycan (show Vcan Proteins) protects oligodendrocyte precursor cells against oxidative stress via interaction with OMI/HtrA2 (show HTRA2 Proteins).

  5. NG2 (show Vcan Proteins) ablation leads to reduced LDL sequestration in the aorta and reduced atherogenesis.

  6. This study demonstrated that a pathway and role for NG2 (show Vcan Proteins) glia in central nerve system homeostasis and mood disorders.

  7. cleaved by ADAM10 (show ADAM10 Proteins) and the gamma-secretase on oligodendrocyte precursor cells

  8. The results of this study indicated that endogenous netrin-1 (show NTN1 Proteins) plays a role in NG2 (show Vcan Proteins)(+) glial cell homeostasis that is distinct from its role in myelination.

  9. The study demonstrates changes in pericyte expression of NG2 (show Vcan Proteins) and PDGFRB (show PDGFRB Proteins) and vascular permeability in the sensory circumventricular organs by chronic osmotic stimulation.

  10. NG2 (show Vcan Proteins) knockdown results in loss of beta1 integrin activation in endothelial cells, revealing a mechanism for NG2 (show Vcan Proteins)-dependent cross talk between pericytes and endothelial cells.

Human Melanoma Associated Chondroitin Sulfate Proteoglycan (MCSP) interaction partners

  1. These data suggest the possible involvement of GD3 and NG2 in pre/pro-tumorigenic events occurring in the complex microenvironment of the tissue surrounding glioblastoma

  2. the ratio of serum proteoglycan 4 (show PRG4 Proteins) to protease C1 inhibitor (show SERPING1 Proteins) may be used for screening of early breast cancer.

  3. The NG2 proteoglycan (show Vcan Proteins) protects oligodendrocyte precursor cells against oxidative stress via interaction with OMI/HtrA2 (show HTRA2 Proteins).

  4. The up-regulation of NG2 is associated with poor prognosis in HCC (show FAM126A Proteins).

  5. Low CSPG4 expression is associated with pancreatic tumors.

  6. These data are consistent with the concept that expression of inhibitory CSPG within the injury scar is an important impediment to regeneration but that NG2+ progenitors derived from ESNLCs can modify the microenvironment

  7. NG2 expression in pediatric brain tumors differs depending upon type and, unlike adult glioma, includes expression on lower-grade tumors.

  8. The results highlight an unprecedented, complex pattern of NG2/CSPG4 isoform expression in foetal and neoplastic CNS

  9. MMP-13 (show MMP13 Proteins) overexpression or exogenous MMP-13 (show MMP13 Proteins) reduces anoikis by more effectively shedding NG2.

  10. Reduced promoter methylation and increased expression of CSPG4 are associated with head and neck squamous cell carcinomas.

NG2 (MCSP) Protein Profile

Protein Summary

A human melanoma-associated chondroitin sulfate proteoglycan plays a role in stabilizing cell-substratum interactions during early events of melanoma cell spreading on endothelial basement membranes. CSPG4 represents an integral membrane chondroitin sulfate proteoglycan expressed by human malignant melanoma cells.

Gene names and symbols associated with MCSP

  • chondroitin sulfate proteoglycan 4 (Cspg4)
  • chondroitin sulfate proteoglycan 4 (CSPG4)
  • ring finger protein 5 (Rnf5)
  • 2410131O05Rik protein
  • 4732461B14Rik protein
  • AA407576 protein
  • AN2 protein
  • HMW-MAA protein
  • MCSP protein
  • MCSPG protein
  • MEL-CSPG protein
  • MSK16 protein
  • Ng2 protein

Protein level used designations for MCSP

AN2 proteoglycan , AN2/NG2 proteoglycan , chondroitin sulfate proteoglycan NG2 , nerve/glial antigen 2 , proteoglycan AN2 , chondroitin sulfate proteoglycan 4 (melanoma-associated) , melanoma chondroitin sulfate proteoglycan , melanoma-associated chondroitin sulfate proteoglycan , HSN tumor-specific antigen , membrane-spanning proteoglycan NG2 , E3 ubiquitin-protein ligase RNF5

GENE ID SPECIES
121021 Mus musculus
1464 Homo sapiens
81651 Rattus norvegicus
54197 Mus musculus
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