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MCAM Proteins

(Melanoma Cell Adhesion Molecule (MCAM))
Plays a role in cell adhesion, and in cohesion of the endothelial monolayer at intercellular junctions in vascular tissue. Its expression may allow melanoma cells to interact with cellular elements of the vascular system, thereby enhancing hematogeneous tumor spread. Could be an adhesion molecule active in neural crest cells during embryonic development. Acts as surface receptor that triggers tyrosine phosphorylation of FYN and PTK2/FAK1, and a transient increase in the intracellular calcium concentration.
MCAM Protein (AA 24-559) (His tag) MCAM Protein (AA 24-559) (His tag) MCAM Protein (AA 24-559) (His tag) (ABIN7275297)

MCAM Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC

MCAM Protein (AA 24-563) (His tag) MCAM Protein (AA 24-563) (His tag) MCAM Protein (AA 24-563) (His tag) (ABIN7275301)

MCAM Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC

MCAM Protein (AA 1-646) (GST tag) MCAM Protein (AA 1-646) (GST tag) MCAM Protein (AA 1-646) (GST tag) (ABIN1310514)

MCAM Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA

MCAM Proteins by Grade

Find MCAM Proteins with a specific Grade. The Grade listed below are among those available. Click on a link to go to the corresponding products.

MCAM Proteins by Origin

Find MCAM Proteins for a variety of species such as anti-Human MCAM, anti-Mouse MCAM, anti-Rat MCAM. The species listed below are among those available. Click on a link to go to the corresponding products.

MCAM Proteins by Source

Here you will find MCAM Proteins proteins organized by several key sources. By clicking on a link, you can access the products. For additional sources, please use our search function.

MCAM Proteins by Protein Type

Here you can find MCAM Proteins proteins categorized by available protein types. Additional protein types can be located using our search function.

MCAM Proteins by Application

Find MCAM Proteins validated for a specific application such as SDS, WB, ELISA, Crys. Some of the available applications are listed below. Click on a link to go to the corresponding products.

Popular MCAM Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (3)
Cat. No. ABIN7275297
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse
Source HEK-293 Cells
Validations
  • (2)
Cat. No. ABIN7275301
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
  • (1)
Cat. No. ABIN1310514
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293T Cells
Validations
  • (2)
Cat. No. ABIN2752854
Quantity 2 μg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3083987
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3126705
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3113632
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3136648
Quantity 1 mg
Datasheet Datasheet
Reactivity Rat
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7505548
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7505436
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7505192
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
Cat. No. ABIN7505639
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7394561
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7394564
Quantity 100 μg
Datasheet Datasheet
Reactivity Rat
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7417588
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our MCAM Proteins

Gao, Zhang, Wang, Liu, He, Liu, Wang, Feng, Yang, Wang, Meng, Yan: "The signalling receptor MCAM coordinates apical-basal polarity and planar cell polarity during morphogenesis." in: Nature communications, Vol. 8, pp. 15279, (2018) (PubMed).

Luo, Duan, Qian, Feng, Wu, Wang, Feng, Yang, Qin, Yan: "Macrophagic CD146 promotes foam cell formation and retention during atherosclerosis." in: Cell research, Vol. 27, Issue 3, pp. 352-372, (2017) (PubMed).

Tu, Zhang, Yan, Luo, Kong, Wen, Ye, Chen, Feng, Liu, Wu, Yan: "CD146 acts as a novel receptor for netrin-1 in promoting angiogenesis and vascular development." in: Cell research, Vol. 25, Issue 3, pp. 275-87, (2015) (PubMed).

Keller, Kalt, Raab, Schachner, Mayrhofer, Kerjaschki, Hantusch: "Selection of scFv Antibody Fragments Binding to Human Blood versus Lymphatic Endothelial Surface Antigens by Direct Cell Phage Display." in: PLoS ONE, Vol. 10, Issue 5, pp. e0127169, (2015) (PubMed).

Ishikawa, Wondimu, Oikawa, Ingerpuu, Virtanen, Patarroyo: "Monoclonal antibodies to human laminin ?4 chain globular domain inhibit tumor cell adhesion and migration on laminins 411 and 421, and binding of ?6?1 integrin and MCAM to ?4-laminins." in: Matrix biology : journal of the International Society for Matrix Biology, Vol. 36, pp. 5-14, (2014) (PubMed).

Ye, Zhang, Tu, Sun, Liu, Lu, Feng, Yang, Liu, Yan: "Wnt5a uses CD146 as a receptor to regulate cell motility and convergent extension." in: Nature communications, Vol. 4, pp. 2803, (2013) (PubMed).

Simon, Martin, Smith, Thaikoottathil, Bowler, Barenkamp, Chu: "Up-regulation of MUC18 in airway epithelial cells by IL-13: implications in bacterial adherence." in: American journal of respiratory cell and molecular biology, Vol. 44, Issue 5, pp. 606-13, (2011) (PubMed).

Aliases for MCAM Proteins

melanoma cell adhesion molecule (MCAM) Proteins
melanoma cell adhesion molecule (Mcam) Proteins
melanoma cell adhesion molecule b (mcamb) Proteins
1-gicerin Proteins
AV025631 Proteins
CD146 Proteins
cd146 Proteins
CD149 Proteins
gicerin Proteins
id:ibd3512 Proteins
mcam Proteins
MCAM Proteins
MUC18 Proteins
Muc18 Proteins
s-endo Proteins
s-gicerin Proteins
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