Melanoma Cell Adhesion Molecule (MCAM) ELISA Kits

Plays a role in cell adhesion, and in cohesion of the endothelial monolayer at intercellular junctions in vascular tissue. Additionally we are shipping MCAM Antibodies (486) and MCAM Proteins (30) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
MCAM 4162 P43121
MCAM 84004 Q8R2Y2
MCAM 78967 Q9EPF2
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Top MCAM ELISA Kits at antibodies-online.com

Showing 9 out of 27 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Human 0.121 ng/mL 0.31-20 ng/mL 96 Tests Log in to see 13 to 16 Days
$560.00
Details
Mouse 0.251 ng/mL 0.62-40 ng/mL 96 Tests Log in to see 13 to 16 Days
$576.00
Details
Rat 0.39 ng/mL 1.56-100 ng/mL   96 Tests Log in to see 15 to 18 Days
$910.56
Details
Guinea Pig 37.5 pg/mL 62.5-4000 pg/mL   96 Tests Log in to see 12 to 14 Days
$715.00
Details
Chicken 0.375 ng/mL 0.625-40 ng/mL   96 Tests Log in to see 12 to 14 Days
$715.00
Details
Monkey 0.375 ng/mL 0.625-40 ng/mL   96 Tests Log in to see 12 to 14 Days
$715.00
Details
Pig 0.375 ng/mL 0.625-40 ng/mL   96 Tests Log in to see 12 to 14 Days
$715.00
Details
Rabbit 18.75 pg/mL 31.25-2000 pg/mL   96 Tests Log in to see 12 to 14 Days
$715.00
Details
Mouse 0.055-40 ng/mL   96 Tests Log in to see 11 to 18 Days
$1,106.88
Details

Top referenced MCAM ELISA Kits

  1. Human MCAM ELISA Kit for Sandwich ELISA - ABIN414788 : Taylan, Sari, Kozaci, Yildiz, Bilge, Coker, Maltas, Gunay, Akkoc: Evaluation of various endothelial biomarkers in ankylosing spondylitis. in Clinical rheumatology 2012 (PubMed)
    Show all 3 references for 414788

  2. Mouse (Murine) MCAM ELISA Kit for Sandwich ELISA - ABIN425012 : Thomann, Longerich, Bazhin, Mier, Schemmer, Ryschich: Selective targeting of liver cancer with the endothelial marker CD146. in Oncotarget 2014 (PubMed)

More ELISA Kits for MCAM Interaction Partners

Zebrafish Melanoma Cell Adhesion Molecule (MCAM) interaction partners

  1. In the context of adult zebrafish spinal cord injury, we proved that Melanoma cell adhesion molecule (MCAM) is beneficial to the recovery, possibly via mechanisms of angiogenensis and inflammation

  2. CD146 regulates convergent extension movement during gastrulation

  3. In addition to the physiological angiogenesis during development, gicerin morphants efficiently blocked the tumor angiogenesis in zebrafish.

  4. CD146 protein expression has a role in vascular development in zebrafish

Human Melanoma Cell Adhesion Molecule (MCAM) interaction partners

  1. MCAM promotes tamoxifen resistance by transcriptionally suppressing ERalpha (show ESR1 ELISA Kits) expression and activating the AKT (show AKT1 ELISA Kits) pathway, followed by induction of epithelial-mesenchymal transition.

  2. High MCAM expression is associated with lung metastasis in malignant melanoma.

  3. Results provide evidence that MUC18 promotes viral infections both in vivo and in vitro.

  4. soluble CD146 is released from the peripheral vasculature in response to venous stretch and may reflect systemic congestion in chronic heart failure patients

  5. CD146/MCAM is the functional galectin-3 (show LGALS3 ELISA Kits)-binding ligand on endothelial cell surfaces responsible for galectin-3 (show LGALS3 ELISA Kits)-induced secretion of metastasis-promoting cytokines.

  6. results indicate that CD146 can be targeted in vivo by the radiolabeled OI-3 antibodies

  7. Findings suggest that decreased CD146 expression in cancer-associated fibroblasts promotes pancreatic cancer progression.

  8. METCAM/MUC18 positively promotes tumorigenesis of human breast cancer SK-BR-3 cells via increasing the signal in survival and proliferation pathways.

  9. sCD146 levels are elevated in patients with systemic sclerosis, but decreased sCD146 levels are observed in SSc (show CYP11A1 ELISA Kits) patients with pulmonary arterial hypertension

  10. Nestin (show NES ELISA Kits) and CD146 are expressed in breast cancer cells with highly aggressive potency. They might contribute to disease relapse in breast cancer by activating the epithelial-mesenchymal transition pathway and assist tumor neovascularization.

Mouse (Murine) Melanoma Cell Adhesion Molecule (MCAM) interaction partners

  1. Results provide evidence that MUC18 promotes viral infections both in vivo and in vitro.

  2. Microphthalmia-associated transcription factor (show MITF ELISA Kits) regulates skin melanoblast migration by repressing the melanoma cell adhesion molecule

  3. Data show that CD146 was significantly higher expressed on tumor endothelium than on the liver.

  4. Conditional knockout of the cd146 gene in the murine endothelium or disruption of netrin-CD146 interaction by a specific anti-CD146 antibody blocks or reduces netrin-1 (show NTN1 ELISA Kits)-induced angiogenesis.

  5. MCAM is expressed by encephalitogenic CD8 (show CD8A ELISA Kits)+ T lymphocytes in experimental autoimmune encephalomyelitis. Blocking or depleting MCAM in vivo reduces chronic neurological deficits in active, transfer, and spontaneous progressive EAE models.

  6. Study demonstrate for the fi rst (show SLC22A12 ELISA Kits) time that host CD146 contributes to hematogenous melanoma cell metastasis through a novel mechanism involving the VEGF (show VEGFA ELISA Kits)/FAK (show PTK2 ELISA Kits)/Ve-cadherin (show CDH5 ELISA Kits) network.

  7. Suggest endothelial CD146 as a target for specific drug delivery in hepatocellular carcinoma.

  8. CD146 plays a dual role on endothelium, facilitating leukocyte extravasations and angiogenesis, thus promoting inflammation.

  9. CD146 deletion in the nervous system impairs appetite, locomotor activity and spatial learning in mice.

  10. Identified a novel negative regulator of angiogenesis, microRNA 329 (miR (show MLXIP ELISA Kits)-329), that directly targeted CD146 and inhibited CD146-mediated angiogenesis in vitro and in vivo.

Pig (Porcine) Melanoma Cell Adhesion Molecule (MCAM) interaction partners

  1. expression of FLK1 (show KDR ELISA Kits), CD146 and microvessel density of angiogenesis at the first week of reperfused acute myocardial infarction.

MCAM Antigen Profile

Antigen Summary

Plays a role in cell adhesion, and in cohesion of the endothelial monolayer at intercellular junctions in vascular tissue. Its expression may allow melanoma cells to interact with cellular elements of the vascular system, thereby enhancing hematogeneous tumor spread. Could be an adhesion molecule active in neural crest cells during embryonic development. Acts as surface receptor that triggers tyrosine phosphorylation of FYN and PTK2/FAK1, and a transient increase in the intracellular calcium concentration.

Gene names and symbols associated with MCAM

  • melanoma cell adhesion molecule (MCAM) antibody
  • melanoma cell adhesion molecule b (mcamb) antibody
  • similar to melanoma cell adhesion molecule (LOC566921) antibody
  • melanoma cell adhesion molecule (Mcam) antibody
  • 1-gicerin antibody
  • AV025631 antibody
  • CD146 antibody
  • CD149 antibody
  • gicerin antibody
  • id:ibd3512 antibody
  • MCAM antibody
  • Muc18 antibody
  • s-endo antibody
  • s-gicerin antibody

Protein level used designations for MCAM

cell surface glycoprotein MUC18 , melanoma adhesion molecule , cell adhesion molecule , similar to melanoma cell adhesion molecule , melanoma cell adhesion molecule , cell surface glycoprotein MUC18-like , Gicerin , S-endo 1 endothelial-associated antigen , cell surface glycoprotein P1H12 , melanoma-associated antigen A32 , melanoma-associated antigen MUC18 , HEMCAM , gicerin , l-gicerin protein , l-gicerin

GENE ID SPECIES
281301 Bos taurus
338313 Danio rerio
566921 Danio rerio
744688 Pan troglodytes
100071414 Equus caballus
100454353 Pongo abelii
100470323 Ailuropoda melanoleuca
4162 Homo sapiens
448832 Gallus gallus
84004 Mus musculus
489368 Canis lupus familiaris
78967 Rattus norvegicus
733617 Sus scrofa
100718224 Cavia porcellus
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