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associates with tyrosine-phosphorylated proteins to link the receptor with its substrate in the plasma membrane [RGD, Feb 2006].. Additionally we are shipping MAGI3 Proteins (4) and many more products for this protein.
Showing 8 out of 11 products:
Human Polyclonal MAGI3 Primary Antibody for WB - ABIN3071457
Wu, Dowbenko, Spencer, Laura, Lee, Gu, Lasky: Interaction of the tumor suppressor PTEN/MMAC with a PDZ domain of MAGI3, a novel membrane-associated guanylate kinase. in The Journal of biological chemistry 2000
Human Polyclonal MAGI3 Primary Antibody for ICC, IF - ABIN4332453
Ni, Kuperwasser: Premature polyadenylation of MAGI3 produces a dominantly-acting oncogene in human breast cancer. in eLife 2016
The altered mRNA isoform, called MAGI3(pPA (show PPA1 Antibodies)), produces a truncated protein that acts in a dominant-negative manner to prevent full-length MAGI3 from interacting with the YAP (show YAP1 Antibodies) oncoprotein, thereby relieving YAP (show YAP1 Antibodies) inhibition and promoting malignant transformation of human mammary epithelial cells.
Results identify MAGI3 as a novel tumor suppressor and provide insight into the pathogenesis of glioma.
Expression levels of MAGI3 and PTEN (show PTEN Antibodies) were significantly downregulated in gliomas.
MAGI-3 competes with NHERF-2 (show SLC9A3R2 Antibodies) to negatively regulate LPA2 (show LPAR2 Antibodies) receptor signaling in colon cancer cells.
Oncogenic human papillomavirus E6 proteins target the MAGI-2 (show MAGI2 Antibodies) and MAGI-3 proteins for degradation [MAGI-2 (show MAGI2 Antibodies), MAGI-3]
In epithelial cells, MAGI-3 was localized with ZO-1 (show TJP1 Antibodies) and cingulin (show CGN Antibodies) at tight junctions, whereas in primary cultured astrocytes it was found in E-cadherin (show CDH1 Antibodies)-based cell-cell contacts and in focal adhesion sites.
These results demonstrate that MAGI-3 interacts directly with LPA(2 (show LPAR2 Antibodies)) and regulates the ability of LPA(2 (show LPAR2 Antibodies)) to activate Erk (show EPHB2 Antibodies) and RhoA (show RHOA Antibodies).
All of the E6 genes from different HPV types displayed similar abilities to mediate the degradation of both p53 (show TP53 Antibodies) and MAGI-3
MAGI-3 has a role in efficient trafficking of TGFalpha to the cell surface in polarized epithelial cells.
associates with tyrosine-phosphorylated proteins to link the receptor with its substrate in the plasma membrane
, membrane-associated guanylate kinase inverted 3
, membrane-associated guanylate kinase, WW and PDZ domain-containing protein 3
, membrane-associated guanylate kinase-related (MAGI-3)
, scaffolding protein SLIPR
, scaffolding-like protein
, membrane-associated guanylate kinase-related 3