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associates with tyrosine-phosphorylated proteins to link the receptor with its substrate in the plasma membrane [RGD, Feb 2006].. Additionally we are shipping MAGI3 Antibodies (11) and MAGI3 Proteins (4) and many more products for this protein.
Results identify MAGI3 as a novel tumor suppressor and provide insight into the pathogenesis of glioma.
Expression levels of MAGI3 and PTEN were significantly downregulated in gliomas.
MAGI-3 competes with NHERF-2 (show SLC9A3R2 ELISA Kits) to negatively regulate LPA2 (show LPAR2 ELISA Kits) receptor signaling in colon cancer cells.
Oncogenic human papillomavirus E6 proteins target the MAGI-2 (show MAGI2 ELISA Kits) and MAGI-3 proteins for degradation [MAGI-2 (show MAGI2 ELISA Kits), MAGI-3]
In epithelial cells, MAGI-3 was localized with ZO-1 (show TJP1 ELISA Kits) and cingulin (show CGN ELISA Kits) at tight junctions, whereas in primary cultured astrocytes it was found in E-cadherin (show CDH1 ELISA Kits)-based cell-cell contacts and in focal adhesion sites.
These results demonstrate that MAGI-3 interacts directly with LPA(2 (show LPAR2 ELISA Kits)) and regulates the ability of LPA(2 (show LPAR2 ELISA Kits)) to activate Erk (show EPHB2 ELISA Kits) and RhoA (show RHOA ELISA Kits).
All of the E6 genes from different HPV types displayed similar abilities to mediate the degradation of both p53 (show TP53 ELISA Kits) and MAGI-3
MAGI-3 has a role in efficient trafficking of TGFalpha to the cell surface in polarized epithelial cells.
associates with tyrosine-phosphorylated proteins to link the receptor with its substrate in the plasma membrane
, membrane-associated guanylate kinase inverted 3
, membrane-associated guanylate kinase, WW and PDZ domain-containing protein 3
, membrane-associated guanylate kinase-related (MAGI-3)
, scaffolding protein SLIPR
, scaffolding-like protein
, membrane-associated guanylate kinase-related 3