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Membrane Protein, Palmitoylated 4 (MAGUK P55 Subfamily Member 4) (MPP4) ELISA Kits

MPP4 encodes a member of the membrane-associated guanylate kinase (MAGUK) protein family, with an N-terminal PDZ domain, a central src homology 3 region (SH3), and a C-terminal guanylate kinase-like (GUK) domain. Additionally we are shipping MPP4 Antibodies (17) and MPP4 Proteins (4) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Human MPP4 MPP4 58538 Q96JB8
Anti-Mouse MPP4 MPP4 227157 Q6P7F1
Anti-Rat MPP4 MPP4 58808  
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More ELISA Kits for MPP4 Interaction Partners

Human Membrane Protein, Palmitoylated 4 (MAGUK P55 Subfamily Member 4) (MPP4) interaction partners

  1. MPP4 (show MMP4 ELISA Kits) gene is highly expressed in retina, but no mutations were identified in a panel of 300 unrelated patients with retinitis pigmentosa.

Mouse (Murine) Membrane Protein, Palmitoylated 4 (MAGUK P55 Subfamily Member 4) (MPP4) interaction partners

  1. Results describe the temporal and spatial expression patterns of mouse membrane palmitoylated protein 4 (Mpp4) gene.

  2. Association of Veli3 (show LIN7C ELISA Kits) with MPP4 suggests that the MAGUKs recruit Veli3 (show LIN7C ELISA Kits) and its binding partners to different cellular regions of the retina where they may participate in the organization of specialized intercellular junctions.

  3. These findings suggest that Mpp4 coordinates Psd95 (show DLG4 ELISA Kits)/Veli3 (show LIN7C ELISA Kits) assembly and maintenance at synaptic membranes. Mpp4 is a critical recruitment factor to organize scaffolds at the photoreceptor synapse.

  4. Results show that Mpp4 organizes a presynaptic protein complex and has a role in modulating Ca(2 (show CA2 ELISA Kits)+) homeostasis and synaptic transmission in rod photoreceptors.

  5. Data suggest that both scaffold proteins PSD95beta and MPP4 are essential for the modulation of PMCA levels at the presynaptic plasma membrane and thereby influence the photoreceptor synaptic calcium handling.

MPP4 Antigen Profile

Antigen Summary

This gene encodes a member of the membrane-associated guanylate kinase (MAGUK) protein family, with an N-terminal PDZ domain, a central src homology 3 region (SH3), and a C-terminal guanylate kinase-like (GUK) domain. The protein is localized to the outer limiting membrane in the retina, and is thought to function in photoreceptor polarity and the organization of specialized intercellular junctions. Alternatively spliced transcript variants have been described, but their biological validity has not been determined.

Gene names and symbols associated with MPP4

  • membrane protein, palmitoylated 4 (LOC784680) antibody
  • membrane protein, palmitoylated 4 (MAGUK p55 subfamily member 4) (MPP4) antibody
  • membrane protein, palmitoylated 4 (MAGUK p55 subfamily member 4) (Mpp4) antibody
  • ALS2CR5 antibody
  • Dlg6 antibody

Protein level used designations for MPP4

MAGUK p55 subfamily member 4 , amyotrophic lateral sclerosis 2 chromosomal region candidate gene 5 protein , discs large homolog 6 , discs, large homolog 6 , mDLG6 , membrane palmitoylated protein 4 , rDLG6

GENE ID SPECIES
784680 Bos taurus
58538 Homo sapiens
227157 Mus musculus
58808 Rattus norvegicus
769757 Gallus gallus
488477 Canis lupus familiaris
100626771 Sus scrofa
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