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Membrane-associated guanylate kinases (MAGUKs) are important adaptor proteins involved in the assembly of protein complexes at sites of cell-cell contact. Additionally we are shipping MPP7 Proteins (4) and many more products for this protein.
Showing 10 out of 30 products:
Human Polyclonal MPP7 Primary Antibody for WB - ABIN1944746
Ota, Suzuki, Nishikawa, Otsuki, Sugiyama, Irie, Wakamatsu, Hayashi, Sato, Nagai, Kimura, Makita, Sekine, Obayashi, Nishi, Shibahara, Tanaka, Ishii, Yamamoto, Saito, Kawai, Isono, Nakamura, Nagahari et al.: Complete sequencing and characterization of 21,243 full-length human cDNAs. ... in Nature genetics 2003
Show all 4 references for ABIN1944746
Chicken Polyclonal MPP7 Primary Antibody for WB - ABIN2785310
Stucke, Timmerman, Vandekerckhove, Gevaert, Hall: The MAGUK protein MPP7 binds to the polarity protein hDlg1 and facilitates epithelial tight junction formation. in Molecular biology of the cell 2007
The association of MPP7 (show CHAF1B Antibodies) single-nucleotide polymorphism rs4317882 gene variant with site-specific bone mineral density was determined.
The Dlg1 (show DLG1 Antibodies)-MPP7 (show CHAF1B Antibodies)-Mals3 (show LIN7C Antibodies) heterotrimer consists of 2 pairs of heterodimeric L27 (show RPL27 Antibodies) domains. These 2 dimers are asymmetric due to the large difference between the N- and C-terminal tandem L27 (show RPL27 Antibodies) domain of MPP7 (show CHAF1B Antibodies).
MPP7 (show CHAF1B Antibodies) is a PDZ protein (show INADL Antibodies) that interacts with human papillomavirus-16 E6 and forms a tripartite complex with LIN7A or LIN7C (show LIN7C Antibodies) and DLG1 (show DLG1 Antibodies), regulating the stability and localization of DLG1 (show DLG1 Antibodies) to cell junctions.
MPP7 (show CHAF1B Antibodies) targets to the lateral surface of epithelial cells via its L27N domain, through an interaction with Dlg1 (show DLG1 Antibodies).
Membrane-associated guanylate kinases (MAGUKs) are important adaptor proteins involved in the assembly of protein complexes at sites of cell-cell contact. They are found in synapses, adherens junctions, and tight junctions. All MAGUKs contain at least 1 PDZ domain, an SH3 domain, and a GUK domain, and many contain 1 or 2 L27 domains, which are involved in multimerization of MAGUKs. MPP7 belongs to the p55 stardust subfamily of MAGUKs, which is named for a Drosophila gene required for establishment of cell polarity in the developing fly embryo (Bohl et al., 2007
MAGUK p55 subfamily member 7
, protein humpback