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MARCH11 is a member of the MARCH family of membrane-bound E3 ubiquitin ligases (EC 220.127.116.11). Additionally we are shipping Membrane-Associated Ring Finger (C3HC4) 11 Antibodies (33) and and many more products for this protein.
results suggest that SAMT1 proteins are physiological substrates of MARCH11 and are delivered to lysosomes through the TGN-MVB pathway by a ubiquitin-dependent sorting system in mouse spermatids
MARCH11 is a member of the MARCH family of membrane-bound E3 ubiquitin ligases (EC 18.104.22.168). These enzymes add ubiquitin (see MIM 191339) to target lysines in substrate proteins, thereby signaling their intracellular transport. March11 appears to have a role in ubiquitin-mediated protein sorting in the trans-Golgi network (TGN)-multivesicular body (MVB) transport pathway (Morokuma et al., 2007
E3 ubiquitin-protein ligase MARCH11
, membrane-associated RING finger protein 11
, membrane-associated RING-CH protein XI