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Membrane-Associated Ring Finger (C3HC4) 2, E3 Ubiquitin Protein Ligase Proteins (MARCH2)

MARCH2 is a member of the MARCH family of membrane-bound E3 ubiquitin ligases (EC 6.3.2.19). Additionally we are shipping Membrane-Associated Ring Finger (C3HC4) 2, E3 Ubiquitin Protein Ligase Antibodies (51) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
MARCH2 224703 Q99M02
MARCH2 51257 Q9P0N8
Rat MARCH2 MARCH2 362849 Q5I0I2
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Top Membrane-Associated Ring Finger (C3HC4) 2, E3 Ubiquitin Protein Ligase Proteins at antibodies-online.com

Showing 4 out of 6 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 49 to 54 Days
$6,041.49
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Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 49 to 54 Days
$4,244.78
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HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
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HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
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MARCH2 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)

Human , ,
,

More Proteins for Membrane-Associated Ring Finger (C3HC4) 2, E3 Ubiquitin Protein Ligase (MARCH2) Interaction Partners

Human Membrane-Associated Ring Finger (C3HC4) 2, E3 Ubiquitin Protein Ligase (MARCH2) interaction partners

  1. Data indicate that E3 ubiquitin ligase (show MUL1 Proteins) MARCH2 co-immunoprecipitated and co-localized with CAL (show FBLIM1 Proteins) and syntaxin 6 (STX6 (show STX6 Proteins)), and show the ubiquitination of CFTR (show CFTR Proteins) by MARCH2.

  2. The MARCH2 E3 ligase activity regulates cell surface beta(2)AR expression and, consequently, its signaling.

  3. Depletion of MARCH-II by small interfering RNA perturbed the trans-Golgi network (TGN (show TG Proteins)) localization of syntaxin 6 (show STX6 Proteins) and TGN38 (show TGOLN2 Proteins)/46

  4. MARCH2 is co-localized with DLG1 (show DLG1 Proteins) at sites of cell-cell contact.

Membrane-Associated Ring Finger (C3HC4) 2, E3 Ubiquitin Protein Ligase (MARCH2) Protein Profile

Protein Summary

MARCH2 is a member of the MARCH family of membrane-bound E3 ubiquitin ligases (EC 6.3.2.19). MARCH enzymes add ubiquitin (see MIM 191339) to target lysines in substrate proteins, thereby signaling their vesicular transport between membrane compartments. MARCH2 reduces surface accumulation of several glycoproteins and appears to regulate early endosome-to-trans-Golgi network (TGN) trafficking (Bartee et al., 2004

Gene names and symbols associated with MARCH2

  • membrane-associated ring finger (C3HC4) 2 (MARCH2)
  • membrane-associated ring finger (C3HC4) 2 (March2)
  • membrane-associated ring finger (C3HC4) 2, E3 ubiquitin protein ligase (MARCH2)
  • membrane-associated ring finger (C3HC4) 2, E3 ubiquitin protein ligase (March2)
  • 9530046H09Rik protein
  • MARCH-II protein
  • RGD1306395 protein
  • RNF172 protein

Protein level used designations for MARCH2

E3 ubiquitin-protein ligase MARCH2 , MARCH-II , membrane-associated RING finger protein 2 , membrane-associated RING-CH protein II , RING finger protein 172 , membrane associated RING-CH finger protein II , syntaxin-6-binding protein

GENE ID SPECIES
508949 Bos taurus
224703 Mus musculus
51257 Homo sapiens
611624 Canis lupus familiaris
362849 Rattus norvegicus
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