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MARCH3 is a member of the MARCH family of membrane-bound E3 ubiquitin ligases (EC 22.214.171.124). Additionally we are shipping Membrane-Associated Ring Finger (C3HC4) 3, E3 Ubiquitin Protein Ligase Proteins (5) and many more products for this protein.
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LPS (show IRF6 Antibodies) activation of TLR4 (show TLR4 Antibodies) significantly increased MARCH3 expression and that siRNA against MARCH3 prevented the decrease in FcgammaRIIb following LPS (show IRF6 Antibodies) treatment.
This gene encodes a member of the membrane-associated RING-CH (MARCH) family. The encoded protein is an E3 ubiquitin-protein ligase that may be involved in regulation of the endosomal transport pathway.
E3 ubiquitin-protein ligase MARCH3
, membrane-associated RING finger protein 3
, membrane-associated RING-CH protein III
, RING finger protein 173