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MARCH4 is a member of the MARCH family of membrane-bound E3 ubiquitin ligases (EC 18.104.22.168). Additionally we are shipping Membrane-Associated Ring Finger (C3HC4) 4, E3 Ubiquitin Protein Ligase Proteins (3) and many more products for this protein.
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Human Polyclonal MARCH4 Primary Antibody for WB - ABIN2774770
Bartee, Mansouri, Hovey Nerenberg, Gouveia, Früh: Downregulation of major histocompatibility complex class I by human ubiquitin ligases related to viral immune evasion proteins. in Journal of virology 2004
Membrane-Associated RING-CH proteins MARCH VIII (show MARCH8 Antibodies) and MARCH IV associate with Bap31 (show BCAP31 Antibodies) and target CD81 (show CD81 Antibodies) and CD44 (show CD44 Antibodies) to lysosomes
MARCH4 is a member of the MARCH family of membrane-bound E3 ubiquitin ligases (EC 22.214.171.124). MARCH enzymes add ubiquitin (see MIM 191339) to target lysines in substrate proteins, thereby signaling their vesicular transport between membrane compartments. MARCH4 reduces surface accumulation of several membrane glycoproteins by directing them to the endosomal compartment (Bartee et al., 2004
E3 ubiquitin-protein ligase MARCH4
, membrane-associated RING finger protein 4
, membrane-associated RING-CH protein IV
, RING finger protein 174
, membrane-associated ring finger (C3HC4) 4