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MARCH4 is a member of the MARCH family of membrane-bound E3 ubiquitin ligases (EC 126.96.36.199). Additionally we are shipping Membrane-Associated Ring Finger (C3HC4) 4, E3 Ubiquitin Protein Ligase Antibodies (65) and many more products for this protein.
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Membrane-Associated RING-CH proteins MARCH VIII (show MARCH8 Proteins) and MARCH IV associate with Bap31 (show BCAP31 Proteins) and target CD81 (show CD81 Proteins) and CD44 (show CD44 Proteins) to lysosomes
MARCH4 is a member of the MARCH family of membrane-bound E3 ubiquitin ligases (EC 188.8.131.52). MARCH enzymes add ubiquitin (see MIM 191339) to target lysines in substrate proteins, thereby signaling their vesicular transport between membrane compartments. MARCH4 reduces surface accumulation of several membrane glycoproteins by directing them to the endosomal compartment (Bartee et al., 2004
E3 ubiquitin-protein ligase MARCH4
, membrane-associated RING finger protein 4
, membrane-associated RING-CH protein IV
, RING finger protein 174
, membrane-associated ring finger (C3HC4) 4