You are viewing an incomplete version of our website. Please click to reload the website as full version.

Membrane-Associated Ring Finger (C3HC4) 5 (MARCH5) ELISA Kits

MARCH5 is a ubiquitin ligase of the mitochondrial outer membrane that plays a role in the control of mitochondrial morphology by regulating mitofusin-2 (MFN2\; MIM 608507) and DRP1 (DNM1L\; MIM 603850) (Nakamura et al., 2006 [PubMed 16936636]).[supplied by OMIM, Mar 2008].. Additionally we are shipping MARCH5 Antibodies (51) and MARCH5 Proteins (4) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Human MARCH5 MARCH5 54708 Q9NX47
Anti-Mouse MARCH5 MARCH5 69104 Q3KNM2
Anti-Rat MARCH5 MARCH5 294079  
How to order from antibodies-online
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Order online
  • orders@antibodies-online.com

More ELISA Kits for MARCH5 Interaction Partners

Rainbow Trout (Oncorhynchus mykiss) Membrane-Associated Ring Finger (C3HC4) 5 (MARCH5) interaction partners

  1. MARCH5 gene is duplicated in rainbow trout, but only fish-specific gene copy is up-regulated after Viral hemorrhagic septicemia virus infection.

Human Membrane-Associated Ring Finger (C3HC4) 5 (MARCH5) interaction partners

  1. Self-clearance mechanism of mitochondrial ligase MARCH5 contributes to mitochondria quality control.MARCH5 is regulated by auto-ubiquitination.

  2. MARCH5 binds MAVS (show MAVS ELISA Kits) only during viral stimulation when MAVS (show MAVS ELISA Kits) forms aggregates, and these interactions require the RING domain of MARCH5 and the CARD domain of MAVS (show MAVS ELISA Kits).

  3. Our results indicate that HDAC6 (show HDAC6 ELISA Kits) is a critical regulator of MFN2 (show MFN2 ELISA Kits) degradation by MARCH5, thus protecting mitochondrial connectivity from hypoxic stress.

  4. A fine balance of Mfn1 (show MFN1 ELISA Kits) levels is maintained by MARCH5-mediated quality control on acetylated Mfn1 (show MFN1 ELISA Kits).

  5. MITOL regulates ER tethering to mitochondria by activating Mfn2 (show MFN2 ELISA Kits) via K192 ubiquitination.

  6. balance between LC1 (show MAP1B ELISA Kits) activation by S-nitrosylation and down-regulation by MITOL is critical for neuronal cell survival

  7. MARCH5 is an authentic E3 ubiquitin ligase and catalyzes K63-linked polyubiquitination of TANK. MARCH5 modulates TLR7 (show TLR7 ELISA Kits) signaling via releasing the inhibitory action of TANK toward TRAF6 (show TRAF6 ELISA Kits).

  8. study found that MITOL interacts with and ubiquitinates DeltaNAT-3Q71, a pathogenic ataxin-3 (show ATXN3 ELISA Kits) mutant, in mitochondria and attenuates its toxicity

  9. lack of MARCH5 results in mitochondrial elongation, which promotes cellular senescence by blocking Drp1 (show CRMP1 ELISA Kits) activity and/or promoting accumulation of Mfn1 (show MFN1 ELISA Kits) at the mitochondria

  10. Results indicate that MITOL plays a protective role against mitochondrial dysfunction caused by the mitochondrial accumulation of mSOD1 via the ubiquitin-proteasome pathway.

Mouse (Murine) Membrane-Associated Ring Finger (C3HC4) 5 (MARCH5) interaction partners

  1. MARCH5 binds MAVS (show MAVS ELISA Kits) only during viral stimulation when MAVS (show MAVS ELISA Kits) forms aggregates, and these interactions require the RING domain of MARCH5 and the CARD domain of MAVS (show MAVS ELISA Kits).

  2. March5 is involved in maintaining mouse-ESC (mESC) pluripotency via catalysis of Prkar1a (show PRKAR1A ELISA Kits) polyubiquitination and inhibition of the Raf (show RAF1 ELISA Kits)/MEK (show MDK ELISA Kits)/ERK (show EPHB2 ELISA Kits) pathway.

  3. A fine balance of Mfn1 (show MFN1 ELISA Kits) levels is maintained by MARCH5-mediated quality control on acetylated Mfn1 (show MFN1 ELISA Kits).

  4. MARCH5 is an authentic E3 ubiquitin ligase and catalyzes K63-linked polyubiquitination of TANK. MARCH5 modulates TLR7 (show TLR7 ELISA Kits) signaling via releasing the inhibitory action of TANK toward TRAF6 (show TRAF6 ELISA Kits).

  5. Results indicate that MITOL plays a protective role against mitochondrial dysfunction caused by the mitochondrial accumulation of mSOD1 via the ubiquitin-proteasome pathway.

MARCH5 Antigen Profile

Antigen Summary

MARCH5 is a ubiquitin ligase of the mitochondrial outer membrane that plays a role in the control of mitochondrial morphology by regulating mitofusin-2 (MFN2\; MIM 608507) and DRP1 (DNM1L\; MIM 603850) (Nakamura et al., 2006

Gene names and symbols associated with MARCH5

  • membrane-associated ring finger (C3HC4) 5 (march5) antibody
  • membrane-associated ring finger (C3HC4) 5 (MARCH5) antibody
  • membrane-associated ring finger (C3HC4) 5 (LOC100341637) antibody
  • membrane-associated ring finger (C3HC4) 5 (March5) antibody
  • 1810015H18Rik antibody
  • 2310008I22Rik antibody
  • 2700055A20Rik antibody
  • 5730499H23Rik antibody
  • E130202O05Rik antibody
  • Mar-05 antibody
  • MARCH-V antibody
  • MARCH5 antibody
  • Marchv antibody
  • MITOL antibody
  • Rnf153 antibody
  • zgc:162966 antibody

Protein level used designations for MARCH5

membrane-associated ring finger (C3HC4) 5 , E3 ubiquitin-protein ligase MARCH5 , MARCH-V , membrane-associated RING finger protein 5 , membrane-associated RING-CH protein V , mitochondrial ubiquitin ligase , ring finger protein 153

GENE ID SPECIES
100302643 Oncorhynchus mykiss
450607 Pan troglodytes
698517 Macaca mulatta
100144728 Xenopus (Silurana) tropicalis
100157340 Sus scrofa
100341637 Oryctolagus cuniculus
561952 Danio rerio
444564 Xenopus laevis
423815 Gallus gallus
54708 Homo sapiens
612766 Canis lupus familiaris
540937 Bos taurus
69104 Mus musculus
294079 Rattus norvegicus
Did you look for something else?