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MS4A6A encodes a member of the membrane-spanning 4A gene family. Additionally we are shipping MS4A6A Proteins (3) and many more products for this protein.
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Human Polyclonal MS4A6A Primary Antibody for EIA, IF - ABIN1450078
Hollingworth, Harold, Sims, Gerrish, Lambert, Carrasquillo, Abraham, Hamshere, Pahwa, Moskvina, Dowzell, Jones, Stretton, Thomas, Richards, Ivanov, Widdowson, Chapman, Lovestone, Powell, Proitsi, Lupton, Brayne, Rubinsztein, Gill, Lawlor, Lynch, Brown, Pa: Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease. in Nature genetics 2011
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high levels of MS4A6A contribute to altered turnover or production of cells with an anti-inflammatory neuroprotective phenotype in favor of cells with a damaging pro-inflammatory phenotype believed to contribute to AD pathology.
data revealed the allele (T) of the rs3865444 polymorphism of the CD33 gene and the allele (C) of the rs610932 polymorphism of the MS4A6A gene may contribute to Alzheimer's disease risk in the Chinese Han population
ABCA7 and the MS4A6A/MS4A4E gene cluster are new Alzheimer's disease susceptibility loci.
This gene encodes a member of the membrane-spanning 4A gene family. Members of this nascent protein family are characterized by common structural features and similar intron/exon splice boundaries and display unique expression patterns among hematopoietic cells and nonlymphoid tissues. The gene encoding this protein is localized to 11q12.1, among a cluster of family members. Alternative splicing of this gene results in several transcript variants that encode different protein isoforms.
CD20 antigen-like 3
, CD20-like precusor
, four-span transmembrane protein 3
, four-span transmembrane protein 3.1
, four-span transmembrane protein 3.2
, membrane-spanning 4-domains subfamily A member 6A