Membrane-Associated Ring Finger (C3HC4) 8, E3 Ubiquitin Protein Ligase (MARCH8) ELISA Kits

MARCH8 is a member of the MARCH family of membrane-bound E3 ubiquitin ligases (EC 6.3.2.19). Additionally we are shipping MARCH8 Antibodies (46) and MARCH8 Proteins (7) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Human MARCH8 MARCH8 220972 Q5T0T0
Anti-Mouse MARCH8 MARCH8 71779 Q9DBD2
Anti-Rat MARCH8 MARCH8 312656  
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More ELISA Kits for MARCH8 Interaction Partners

Human Membrane-Associated Ring Finger (C3HC4) 8, E3 Ubiquitin Protein Ligase (MARCH8) interaction partners

  1. Salmonella typhimurium SteD caused MARCH8-dependent ubiquitination and depletion of surface-localized mature MHC class II antigens.

  2. YopJ mediates Ser- and Lys-acetylation and affects auto-ubiquitination of ubiquitin ligase MARCH8 in human cells.

  3. Kaposi's sarcoma-associated herpesvirus RTA not only downregulated HLA-DRalpha at the protein level through direct binding and degradation through the proteasome pathway but also indirectly downregulated the protein level of HLA-DRalpha by enhancing the expression of MARCH8, a member of the membrane-associated RING-CH (MARCH) proteins.

  4. MARCH8 is highly expressed in terminally differentiated myeloid cells, and that it is a potent antiviral protein that targets viral envelope glycoproteins and reduces their incorporation into virions.

  5. MARCH 8 mediates the ubiquitination and lysosomal degradation of the transferrin receptor.

  6. MARCH8 protein localizes in lysosomes in HeLa cells

  7. endogenous MARCH-8 regulates the steady-state cell surface expression of TRAIL-R1.

  8. MARCH8-mediated polyubiquitination and degradation of IL1RAP (show IL1RAP ELISA Kits) is an important mechanism for negative regulation of IL-1beta (show IL1B ELISA Kits)-induced signaling pathways.

  9. MARCH8 expression led to direct ubiquitination of CD98 (show SLC3A2 ELISA Kits) and routing of CD98 (show SLC3A2 ELISA Kits) to late endosomes/lysosomes

  10. Membrane-Associated RING-CH proteins MARCH VIII and MARCH IV associate with Bap31 (show BCAP31 ELISA Kits) and target CD81 (show CD81 ELISA Kits) and CD44 (show CD44 ELISA Kits) to lysosomes

Zebrafish Membrane-Associated Ring Finger (C3HC4) 8, E3 Ubiquitin Protein Ligase (MARCH8) interaction partners

  1. March 8 functions in the embryo to modulate the strength of cell adhesion by regulating the localization of E-cadherin (show CDH1 ELISA Kits).

Mouse (Murine) Membrane-Associated Ring Finger (C3HC4) 8, E3 Ubiquitin Protein Ligase (MARCH8) interaction partners

  1. orchestrated regulation of MHC II surface expression in thymic epithelial cells by MARCH 8 and CD83 (show CD83 ELISA Kits) plays a major role in CD4 (show CD4 ELISA Kits)(+) T cell selection.

  2. CD83-mediated MHCII stabilization through antagonism of March8 as a novel functional adaptation of cortical epithelial cells for T cell selection.

MARCH8 Antigen Profile

Antigen Summary

MARCH8 is a member of the MARCH family of membrane-bound E3 ubiquitin ligases (EC 6.3.2.19). MARCH enzymes add ubiquitin (see MIM 191339) to target lysines in substrate proteins, thereby signaling their vesicular transport between membrane compartments. MARCH8 induces the internalization of several membrane glycoproteins (Goto et al., 2003

Gene names and symbols associated with MARCH8

  • membrane-associated ring finger (C3HC4) 8, E3 ubiquitin protein ligase (MARCH8) antibody
  • membrane-associated ring finger (C3HC4) 8 (march8) antibody
  • membrane-associated ring finger (C3HC4) 8 (March8) antibody
  • membrane-associated ring finger (C3HC4) 8, E3 ubiquitin protein ligase (March8) antibody
  • membrane-associated ring finger (C3HC4) 8, E3 ubiquitin protein ligase (march8) antibody
  • membrane-associated ring finger (C3HC4) 8 (MARCH8) antibody
  • membrane-associated ring finger (C3HC4) 8 (LOC100221220) antibody
  • 1300017E09Rik antibody
  • c-MIR antibody
  • Mar-08 antibody
  • MARCH-VIII antibody
  • MARCH8 antibody
  • Mir antibody
  • RNF178 antibody
  • zgc:171495 antibody

Protein level used designations for MARCH8

E3 ubiquitin-protein ligase MARCH8 , RING finger protein 178 , c-mir, cellular modulator of immune recognition , cellular modulator of immune recognition (c-MIR) , membrane-associated RING finger protein 8 , membrane-associated RING-CH protein VIII , MARCH-VIII , cellular modulator of immune recognition , membrane-associated ring finger (C3HC4) 8

GENE ID SPECIES
220972 Homo sapiens
567818 Danio rerio
71779 Mus musculus
312656 Rattus norvegicus
423770 Gallus gallus
448095 Xenopus (Silurana) tropicalis
450431 Pan troglodytes
495072 Xenopus laevis
540667 Bos taurus
606989 Canis lupus familiaris
100062110 Equus caballus
100221220 Taeniopygia guttata
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