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Meningioma Expressed Antigen 5 (Hyaluronidase) (MGEA5) ELISA Kits

The dynamic modification of cytoplasmic and nuclear proteins by O-linked N-acetylglucosamine (O-GlcNAc) addition and removal on serine and threonine residues is catalyzed by OGT (MIM 300255), which adds O-GlcNAc, and MGEA5, a glycosidase that removes O-GlcNAc modifications (Gao et al., 2001 [PubMed 11148210]).[supplied by OMIM, Mar 2008].. Additionally we are shipping MGEA5 Antibodies (38) and MGEA5 Proteins (5) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Human MGEA5 MGEA5 10724 O60502
Anti-Mouse MGEA5 MGEA5 76055 Q9EQQ9
Anti-Rat MGEA5 MGEA5 154968 Q8VIJ5
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Catalog No. Reactivity Sensitivity Range Quantity Supplier Delivery Price Details
Chicken
96 Tests Log in to see 16 to 21 Days
$999.43
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More ELISA Kits for MGEA5 Interaction Partners

Human Meningioma Expressed Antigen 5 (Hyaluronidase) (MGEA5) interaction partners

  1. E2F1 (show E2F1 ELISA Kits) negatively regulates both Ogt (show OGT ELISA Kits) and Mgea5 expression in an Rb1 (show RB1 ELISA Kits) protein-dependent manner.

  2. OGA overexpression in endothelial cells improves endothelial function and may have a beneficial effect on coronary vascular complications in diabetes.

  3. Amino acid composition of splice variants, post-translational modifications, and stable associations with regulatory proteins influence subcellular distribution/substrate specificity of OGA and OGT (O-linked N-acetylglucosamine transferase (show OGT ELISA Kits)). [REVIEW]

  4. This work identifies the first target of miR (show MLXIP ELISA Kits)-539 in the heart and the first miRNA that regulates OGA.

  5. Report the presence of TGFBR3 (show TGFBR3 ELISA Kits) and/or MGEA5 rearrangements in pleomorphic hyalinizing angiectatic tumors and the spectrum of related neoplasms.

  6. Estrogen replacement therapy and plyometric training influence muscle OGT and OGA gene expression, which may be one of the mechanisms by which HRT and PT prevent aging-related loss of muscle mass.

  7. O-linked beta-N-acetylglucosaminylation (O-GlcNAcylation) in primary and metastatic colorectal cancer clones and effect of N-acetyl-beta-D-glucosaminidase silencing on cell phenotype and transcriptome.

  8. Data show that the interplay between O-GlcNAc (show OGT ELISA Kits) and phosphorylation on proteins and indicate that these effects can be mediated by changes in hOGT and hOGA (show OAT ELISA Kits) kinetic activity.

  9. Analysis of urinary content of MGEA5 and OGT (show OGT ELISA Kits) may be useful for bladder cancer diagnostics.

  10. Decrease in MGEA5 and increase in O-GlcNAc transferease expression in higher grade tumors suggests that increased O-GlcNAc modification may be implicated in breast tumor progression and metastasis.

Mouse (Murine) Meningioma Expressed Antigen 5 (Hyaluronidase) (MGEA5) interaction partners

  1. Oga(+/-) mice resist high-fat diet-induced obesity with ameliorated hepatic steatosis and improved glucose metabolism

  2. plays a critical role in placental vasculogenesis by modulating HIF-1alpha (show HIF1A ELISA Kits) stabilization

  3. E2F1 (show E2F1 ELISA Kits) negatively regulates both Ogt (show OGT ELISA Kits) and Mgea5 expression in an Rb1 (show RB1 ELISA Kits) protein-dependent manner.

  4. Conditional disruption of the O-GlcNAcase in mice leads to metabolic deregulation and semi-penetrant perinatal lethality.

  5. This work identifies the first target of miR (show MLXIP ELISA Kits)-539 in the heart and the first miRNA that regulates OGA.

  6. The O-GlcNAcase active site resembles those of glycosidases which carry out the hydrolysis of GlcNAc linkages in a substrate-assisted acid-base manner.

Pig (Porcine) Meningioma Expressed Antigen 5 (Hyaluronidase) (MGEA5) interaction partners

  1. Data suggest that enzymes in hexosamine biosynthesis pathway and downstream protein O-GlcNAcylation are important for preimplantation development; these include Oga, Gfpt (glutamine-fructose-6-P aminotransferase), and Ogt (O-GlcNAc transferase).

MGEA5 Antigen Profile

Antigen Summary

The dynamic modification of cytoplasmic and nuclear proteins by O-linked N-acetylglucosamine (O-GlcNAc) addition and removal on serine and threonine residues is catalyzed by OGT (MIM 300255), which adds O-GlcNAc, and MGEA5, a glycosidase that removes O-GlcNAc modifications (Gao et al., 2001

Gene names and symbols associated with MGEA5

  • meningioma expressed antigen 5 (hyaluronidase) (MGEA5) antibody
  • meningioma expressed antigen 5 (hyaluronidase) (Mgea5) antibody
  • 2810009A20Rik antibody
  • 4833427O07Rik antibody
  • 5830447M11Rik antibody
  • AA408215 antibody
  • Hy5 antibody
  • MEA5 antibody
  • mKIAA0679 antibody
  • Ncoat antibody
  • O-GLCNACASE antibody
  • OGA antibody

Protein level used designations for MGEA5

O-GlcNAcase , bifunctional protein NCOAT , hyaluronidase in meningioma , meningioma-expressed antigen 5 , nuclear cytoplasmic O-GlcNAcase and acetyltransferase

GENE ID SPECIES
10724 Homo sapiens
76055 Mus musculus
154968 Rattus norvegicus
477802 Canis lupus familiaris
100152585 Sus scrofa
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